Retinal laser accidents: mechanisms and management
Source abstract
Abstract
Retinal injuries from industrial or military lasers are uncommon, but laser accidents can injure the retina and destroy central vision, permanently. Key principles of retinal anatomy and psychophysics provide a basis for understanding laser-retinal interactions, retinal trauma, and treatment options. Immediate vision loss after a laser accident depends primarily on the location and extent of retinal damage and vitreoretinal hemorrhage. Prompt ophthalmic evaluation of accident victims is indicated to determine the nature and severity of injuries to the cornea, iris, crystalline lens, and retina. There are no clinically proven therapies for minimizing the acute effects of retinal laser injuries, but vitreoretinal surgery is useful for managing complications such as persistent vitreous hemorrhages, macular holes, and epiretinal membranes. The best way to manage laser trauma is to prevent it.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Ocular and Laser Science Research · Traumatic Ocular and Foreign Body Injuries · Historical and Scientific Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Ophthalmology, University of Kansas Medical Center, Kansas City, Kansas 66160-7379
References (59)
Show source-provided references
1. The retinal pigment epithelium: I. Comparative histology10.1001/archopht.1967.00980030643016 ↗
2. The fractal properties of retinal vessels: embryological and clinical implications10.1038/eye.1990.33 ↗
3. Remote nerve fiber bundle alterations in the retina as caused by argon laser photocoagulation10.1038/248433a0 ↗
4. Structural aspects of laser-induced damage and their functional implications10.1097/00004032-198905000-00003 ↗
5. Battlefield laser weapons: an assessment of systems, hazards, injuries and ophthalmic resources required for treatment
6. Nerve fiber layer (NFL) degeneration associated with acute Q-switched laser exposure in the non-human primate
7. Contemporary optics and ocular pathology10.1016/0039-6257(78)90092-9 ↗
8. Über die indirekte sehschärfe
9. Peripheral visual acuity with special reference to scotopic illumination
10. Peripheral visual acuity10.1001/archopht.1966.00970050502011 ↗
11. Extrafoveal visual acuity as measured with snellen test-letters10.1016/S0002-9394(41)90648-7 ↗
12. Visual fields and electroretinography following extensive photocoagulation10.1001/archopht.1975.01010020575004 ↗
13. The effect of panretinal laser photocoagulation on visual acuity, visual fields and on subjective visual impairment in preproliferative and early proliferative diabetic retinopathy10.1111/j.1755-3768.1994.tb07181.x ↗
14. Potential retinal hazards: instrument and environmental light sources10.1016/S0161-6420(83)80019-0 ↗
15. Laser photodisruptors: damage mechanisms, instrument design and safety10.1016/S0161-6420(83)80025-6 ↗
16. Classification of ophthalmic photosurgery
17. Three major pathologic processes caused by light in the primate retina: a search for mechanisms
18. Light damage revisited: converging evidence, diverging views?10.1007/BF00186512 ↗
19. Photochemical lesions in the primate retina under conditions of elevated blood oxygen
20. Oxygen dependence of damage by 435 nm light in cultured retinal epithelium10.3109/02713688408997202 ↗
21. Possible mechanisms of photoreceptor damage by light in mammalian eyes10.1016/0042-6989(80)90055-3 ↗
22. Destructive light adaptation
23. Light and macular degeneration: a biophysical and clinical perspective10.1038/eye.1987.49 ↗
24. Two classes of photochemical damage of the retina
25. Retinal damage by light in rats
26. Differential spectral photic damage to primate cones10.1016/0042-6989(80)90049-8 ↗
27. Basic mechanisms underlying the production of photochemical lesions in the mammalian retina10.3109/02713688408997198 ↗
28. Retinal sensitivity to damage from short wavelength light10.1038/260153a0 ↗
29. Action spectrum for retinal injury from near-ultraviolet radiation in the aphakic monkey10.1016/0002-9394(82)90529-3 ↗
30. Maculopathy from hand held diode laser pointer10.1001/archopht.117.11.1557 ↗
31. Laser pointer maculopathy10.1016/S0002-9394(99)00017-3 ↗
32. Blinded by the light-NOT10.1001/archopht.117.11.1547 ↗
33. Laser pointer-induced macular injury10.1016/S0002-9394(98)00254-2 ↗
34. Decreasing retinal photocoagulation damage: principles and techniques10.3109/08820539909069538 ↗
35. Near infrared laser ocular bioeffects10.1097/00004032-198905000-00005 ↗
36. Bioeffects of near infrared lasers10.2351/1.521841 ↗
37. The thermal nature of retinal laser photocoagulation10.1016/S0014-4835(66)80033-7 ↗
38. Thermal and mechanical mechanisms in laser damage to the retina
39. Retinal temperature increases produced by intense light sources10.1364/JOSA.60.000264 ↗
40. Retinal injury due to industrial laser burns10.1016/S0161-6420(81)35068-4 ↗
41. Laser retinal injury10.1093/milmed/150.4.177 ↗
42. Clinical observations of six cases of laser injury to the eye10.1097/00004032-198905000-00016 ↗
43. Accidental human laser injuries from military laser systems10.1117/12.237505 ↗
44. Experimental subretinal hemorrhage in rabbits10.1016/0002-9394(82)90301-4 ↗
45. Complications of argon laser photocoagulation
46. Long-term follow up of accidental parafoveal laser burns10.1097/00006982-199313020-00012 ↗
47. But is it really light damage?
48. Accidental industrial laser burn of the macula
49. Laser injury to multiple retinal foci10.1002/lsm.1900070611 ↗
50. Neuroprotective therapy for argon-laser induced retinal injury10.1006/exer.1997.0360 ↗
51. The effect of high-dose methylprednisolone on laser-induced retinal injury in primates: an electron microscopic study10.1007/BF01880672 ↗
52. Pretreatment with hydroxyethyl starch-deferoxamine but not methylprednisolone reduces secondary injury to retina after laser irradiation
53. Ciprofloxacin and dexamethasone inhibit the proliferation of human retinal pigment epithelial cells in culture10.3109/02713689109003447 ↗
54. Limiting photoreceptor death and deconstruction during experimental retinal detachment: the value of oxygen supplementation10.1016/S0002-9394(99)00104-X ↗
55. Does hyperoxygenation limit retinal degeneration after retinal detachment?
56. Hyperthermia protects against light damage in the rat retina10.1126/science.3175623 ↗
57. Role of body temperature in the definition of retinal burn threshold
58. Accelerated healing of laser-injured rabbit retina by basic fibroblast growth factor
59. MK-801 has neuroprotective and antiproliferative effects in retinal laser injury