journal article·2026-02-01

Mechanical properties and biocompatibility of Ta/Ti6Al4V composite porous structures printed using selective laser melting

Gaolin Yang, Yuxuan Xiong, Lisha Fan, Shuowen Zhang, Hejie Li, Guolong Wu, Xiaoyu Ding, Qiwei Song, Jianhua Yao

Journal of Laser Applications· Volume 38· Issue 1
Publisher page

Abstract

The growing aging population and the increasing incidence of traumatic injuries have jointly intensified the clinical demand for bone repair materials and technologies. Tantalum (Ta) and titanium (Ti) alloys are widely used in clinical orthopedics—such as joint replacements, cranial implants, and spinal implants—due to their excellent biocompatibility and mechanical properties. Notably, tantalum exhibits outstanding biological performance, including superior osseointegration and antibacterial properties. In recent years, researchers have focused on fabricating tantalum coatings on titanium and its alloys to combine the advantages of both materials. Various coating techniques have been developed, including chemical vapor deposition, magnetron sputtering, vacuum plasma spraying, and selective laser melting (SLM). However, these methods still present limitations such as limited bonding strength, poor controllability of pore size and porosity, and mismatched elastic modulus. In this study, a Ta/Ti6Al4V composite porous structure with uniform pores was successfully prepared using SLM. The structure achieved metallurgical bonding between the two materials, with a bonding strength of up to 447.3 MPa and a compressive yield strength ranging from 66.1 to 87.4 MPa. Thanks to the fully porous design, the elastic modulus was significantly reduced (1.9–2.9 GPa), matching that of human bone tissue; in vitro experiments confirmed that its overall biocompatibility is comparable to that of pure Ta. Corrosion resistance tests demonstrated that the Ta/Ti6Al4V composite porous structures exhibit good chemical stability in simulated body fluid. The Ta/Ti6Al4V composite porous structures show promising potential as an orthopedic implant.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Cellular and Composite Structures · Additive Manufacturing Materials and Processes · Titanium Alloys Microstructure and Properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Mechanical Engineering, Zhejiang University of Technology 1 , Hangzhou 310023,

High-End Laser Manufacturing Equipment Collaborative Innovation Center 2 , Hangzhou, Zhejiang 310023,

Institute of Laser Advanced Manufacturing, Zhejiang University of Technology 3 , Hangzhou, Zhejiang 310023,

Moganshan Institute ZJUT 4 , Deqing 313200,

Zhijiang College of Zhejiang University of Technology 5 , Shaoxing, Zhejiang 312030,

Funding

The Nationl Key Research and Development Program of China · The National Natural Science Foundation of China · The Key R&D Program of Zhejiang · The Zhejiang Provincial Postdoctoral Science Foundation

References (33)

Show source-provided references
1. Biomaterials as implants in the orthopedic field for regenerative medicine: Metal versus synthetic polymers10.3390/polym15122601 ↗
2. Porous metal implants: Processing, properties, and challenges10.1088/2631-7990/acdd35 ↗
3. 3D printing metal implants in orthopedic surgery: Methods, applications and future prospects10.1016/j.jot.2023.08.004 ↗
4. Biodegradable Mg alloys for orthopedic implants—A review10.1016/j.jma.2021.06.024 ↗
5. Additive manufacturing technology for porous metal implant applications and triple minimal surface structures: A review10.1016/j.bioactmat.2018.12.003 ↗
6. Improving biocompatibility for next generation of metallic implants10.1016/j.pmatsci.2022.101053 ↗
7. Phase constituents and microhardness of laser alloyed Ti–6Al–4V alloy10.2351/1.4906388 ↗
8. Mechanical properties of Ti6Al4V alloy with porous structure prepared by selective laser melting10.12442/j.issn.1002-185X.20210830 ↗
9. Porous tantalum structures for bone implants: Fabrication, mechanical and in vitro biological properties10.1016/j.actbio.2010.01.046 ↗
10. Mechanical and biological properties of graded porous tantalum coatings deposited on titanium alloy implants by vacuum plasma spraying10.1016/j.surfcoat.2019.05.003 ↗
11. Direct laser processing of a tantalum coating on titanium for bone replacement structures10.1016/j.actbio.2009.11.021 ↗
12. Porous tantalum structure integrated on Ti6Al4V base by laser powder bed fusion for enhanced bony-ingrowth implants: In vitro and in vivo validation10.1016/j.bioactmat.2021.05.025 ↗
13. Evaluation of an artificial vertebral body fabricated by a tantalum-coated porous titanium scaffold for lumbar vertebral defect repair in rabbits10.1038/s41598-018-27182-x ↗
14. Porous tantalum coatings prepared by vacuum plasma spraying enhance bmscs osteogenic differentiation and bone regeneration in vitro and in vivo10.1371/journal.pone.0066263 ↗
15. Effect of magnetron-sputtered monolayer Ta and multilayer Ti-Zr-Ta and Zr-Ti-Ta coatings on the surface properties of biomedical Ti-6Al-4V alloy10.1016/j.matlet.2022.132464 ↗
16. Tantalum-coated pedicle screws enhance implant integration10.1016/j.colsurfb.2017.08.059 ↗
17. Microstructure and mechanical properties of Al2O3 dispersion strengthened Cu by laser in-situ aluminum thermal reduction processing10.1016/j.matdes.2025.114547 ↗
18. How useful is SBF in predicting in vivo bone bioactivity10.1016/j.biomaterials.2006.01.017 ↗
19. Microstructure and biocompatibility of porous-Ta/Ti-6Al-4V component produced by laser powder bed fusion for orthopedic implants10.1016/j.matchar.2021.111554 ↗
20. Dependence of yield strain of human trabecular bone on anatomic site10.1016/S0021-9290(01)00011-2 ↗
21. C. Yan , “Preparation and biocompatibility of porous titanium-tantalum alloy,” M.S. thesis, (Beijing Institute of Technology, China, 2017).
22. Selective laser melting of pure tantalum: Densification, microstructure and mechanical behaviors10.1016/j.msea.2017.09.083 ↗
23. A literature review study on atomic ions dissolution of titanium and its alloys in implant dentistry10.3390/ma12030368 ↗
24. Corrosion of metallic biomaterials: A review10.3390/ma12030407 ↗
25. Study on improving corrosion resistance of tantalum coating by anodic oxidation10.20964/2021.07.13 ↗
26. Corrosion behavior of niobium, tantalum and their alloys in Hot hydrochloric and phosphoric acid solutions10.1016/S0263-4368(99)00034-7 ↗
27. Investigation of aqueous slurry erosion-corrosion behaviour of tantalum in different pH solutions10.1016/j.ijrmhm.2023.106427 ↗
28. Surface characterization and preparation of Ta coating on Ti6Al4V alloy10.1016/j.jallcom.2015.04.207 ↗
29. Influence of concentration and temperature on the corrosion behavior of titanium, titanium-20 and 40% tantalum alloys and tantalum in sulfuric acid solutions10.1016/j.matchemphys.2007.02.026 ↗
30. Y. Sun , “Experimental study on biocompatibility and osseointegration capability of novel low elastic modulus titanium alloy TiNbZrTaSi,” Ph.D. thesis, (Jilin University, China, 2016).
31. Corrosion behaviour of Ti–Nb–Sn shape memory alloys in different simulated body solutions10.1016/j.msea.2006.01.131 ↗
32. Corrosion resistance and biocompatibility of Ti–Ta alloys for biomedical applications10.1016/j.msea.2005.03.032 ↗
33. Biocompatibility of a fish scale-derived artificial cornea: Cytotoxicity, cellular adhesion and phenotype, and in vivo immunogenicity10.1016/j.biomaterials.2015.11.015 ↗