article·2004-01-01

Effects of Poly(Ethylene Glycol) on Preparation of AmorphousCalcium Phosphate

Yan Li, Weng Wen-Jian, Kui Cheng, Piyi Du, Shen Ge, Han Gao-rong

Abstract

A stable amorphous calcium phosphate (ACP) was prepared by a wet chemical method at a low temperature in the presence of poly(ethylene glycol) (PEG). The effects of PEG:CaCl2 ratios and the molecule weight of PEG on the stability of ACP in the aqueous solution were investigated. The results show that the optimized preparation conditions for stable ACP are PEG:CaCl2 ratio of 1:1 and the PEG molecule weight of 10000. The role of PEG in stabilizing ACP in the aqueous solution is that PEG is easy to exist in the interstices between the ACP Ca9(PO4)6 clusters and adsorbed around ACP particles, and inhibits ACP transformations to crystalline hydroxyapatite.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials · biodegradable polymer synthesis and properties · Pigment Synthesis and Properties

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