Osseointegration of Plasma-sprayed Titanium Coating after Alkali Modification

Plasma sprayed titanium coatings were modified by alkali treatment process. The bone bonding ability of titanium coatings was investigated in vivo implantation in dog's femur. The bond strength between bone and titanium coatings was also measured by push-out test. The results obtained indicate that the alkali-modified coating not only bond directly to bone, but also accelerate the ingrowth of bone. After 1 month of implantation, the alkali-modified coatings show good osseointegration and higher shear strength. The mechanism of improving osseointegration of alkali-modified titanium coating described can be attributed to the changes in surface micro-topography and chemistry composition after alkali modification.