Properties of Surface Modified 45S5/PDLLA Composite Films Treated with Boiling Water

45S5 bioactive glasses(BGs) were surface-modified with dodecyl alcohol through esterification reaction to get 45S5/PDLLA composite films.The properties of the composite films before and after treatment in boiling water for 20min were investigated.The results show that water contact angles of the composite films decrease sharply after the boling water treatment,indicating the improvement of the hydrophilicity of the composite films.Furthermore,after boiling water treatment,the tensile strength of the composite films decrease slightly,and is still higher than that of 45S5 BGs/PDLLA composite films,which illustrate that the treatment in boiling water does not affect the homogeneous dispersion of BGs particles in PDLLA matrix.Most importantly,cells on the composite films after hydrolysis show the highest proliferation rate and differentiation level.