Preparation and Characterization of Bioactive Poly (Lactic Acid)/SiO2-CaO Composite Membranes
Source abstract
Abstract
以聚乳酸、正硅酸乙酯和硝酸钙为原料, 采用溶胶-凝胶方法制备了不同比例的聚乳酸/SiO 2 -CaO多孔复合薄膜. 采用扫描电子显微镜和红外光谱仪对薄膜的微观结构和组成进行分析, 并利用表面Zeta电位测定仪对其表面电位进行表征, 通过模拟体液浸泡实验和MTT方法对薄膜的生物活性和细胞毒性进行评价. 结果表明: 复合薄膜在模拟体液中经过7d的浸泡, 薄膜表面形成了环状结构的类骨磷灰石层; 随着SiO 2 -CaO含量增加, 复合薄膜表面微孔的孔径变小, 薄膜表面Zeta电位变负, 诱导类骨磷灰石沉积的能力增强; MTT实验证实复合薄膜对MG-63细胞没有毒性且有利于细胞的增殖.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · biodegradable polymer synthesis and properties · Graphene and Nanomaterials Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (19)
Show source-provided references
1. Cai X10.1016/j.actbio.2009.03.005 ↗
2. Liu X Y10.1016/S0142-9612(00)00386-0 ↗
3. Weng J10.1016/S0142-9612(97)00022-7 ↗
4. Tokiwa Y10.1007/s00253-006-0488-1 ↗
5. Hofacker R10.1016/S0300-9440(02)00045-0 ↗
6. Liu X Y10.1016/S0142-9612(01)00210-1 ↗
7. Ni S
8. Yan S F10.1016/j.matlet.2006.10.023 ↗
9. Zhang Z10.1016/j.biomaterials.2006.03.006 ↗
10. Janorkar A V10.1021/ma049056u ↗
11. Murugan R
12. Kim I Y
13. Gao T J10.1016/S0142-9612(00)00288-X ↗
14. Liu H C10.1016/j.biomaterials.2003.10.098 ↗
15. Kokubo T10.1016/j.biomaterials.2006.01.017 ↗
16. Takadama H10.1021/cm0008718 ↗
17. Kokubo T10.1016/0022-3093(90)90199-V ↗
18. Maiti P10.1021/cm020391b ↗
19. Schugens C10.1002/jbm.820291106 ↗