A Novel Hollow Hydroxyapatite Microspheres/Chitosan Composite Drug Carrier for Controlled Release
Source abstract
Abstract
A novel composite drug carrier with excellent sustained and pH-sensitive release performance was prepared by mixing hollow hydroxyapatite (HA) microspheres and chitosan solution with pH-sensitive characteristics. The hollow HA microspheres with mesopores filled on their multilayered spherical shell were obtained by converting borate glass with a novel composition of 19Na 2 O-17CaO-64B 2 O 3 (wt%). The structure, phase composition and morphology of HA microspheres were characterized by SEM, SEM-EDS, XRD, FTIR and N 2 adsorption-desorption measurements.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Hydrogels: synthesis, properties, applications · biodegradable polymer synthesis and properties
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