Source abstract
Abstract
The contact layer of traditional medical dressing is easy to adhere to the new wound granulation tissue, which brings the deficiency of secondary wound injury. This work assumed that low-cost and soft mesh spunlace nonwoven was used as medical dressing contact layer. After micro-nano SiO 2 modification, polydimethylsiloxane (PDMS)/n-heptane were uniformly sprayed on the surface of materials. PDMS modification was studied by using the three-factor three-level orthogonal experiment. The results showed that when the PDMS concentration was 1%, the heat treatment temperature and time were 120°C and 12 h respectively, material possessed the optimal hydrophobicity and its water contact angle (CA) was 151.0 ± 1.1°. Meanwhile, the hydrophobicity, microstructure, thermogravimetry, composition, tensile mechanics, adhesion resistance and durability of materials with/without treatment were compared. It was proved that PDMS was indeed grafted onto the material and could effectively improve the hydrophobicity in coordination with micro-nano SiO 2 without affecting the mesh structure of material. The machine direction (MD) and cross-machine direction (CD) strength of material decreased but the elongation increased slightly. The MD and CD peeling energy was 129.7 ± 33.9 J/m 2 and 98.1 ± 38.3 J/m 2 , respectively. Moreover, the water CA of material modified by micro-nano SiO 2 /PDMS was still 139.4 ± 1.4° after 10 friction stroke tests, indicating that the modified material possessed the great durability. Overall, this study can provide the research basis for the development of anti-adhesion medical dressing contact layer.
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Affiliations
Key Laboratory of Clean Dyeing and Finishing Technology of Zhejiang Province, Shaoxing University, Shaoxing, Zhejiang, China
Shaoxing Fuqing Health Products Co., Ltd, Shaoxing, Zhejiang, China
Hangzhou Hanford Technology Co., Ltd, Hangzhou, China
Zhejiang Baoren Hezhong Technology Co., Ltd, Shaoxing, Zhejiang, China
Department of Biomedical Engineering City University of Hong Kong, Hong Kong SAR, China
Funding
Zhejiang Provincial science and technology Department research and development project · Student Scientific Research Project of Shaoxing University · Science and Technology Guiding Project of China National Textile Industry Council · National Natural Science Foundation of China Youth Found · National Innovation and Entrepreneurship Training Program of College Students