Biomimetic Ca-P Coatings on Polyacrylic Acid Modified Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Films
Source abstract
Abstract
A biomimetic Ca-P coating has been achieved on poly(acrylic acid) (PAA) grafted poly(3-hydroxybutyrate-co-3-hydroxyvalerate) films (PHBV), aiming at acquiring active bone-bonding capacity for bioimplants. PAA-g-PHBV with 21% graft yield (PAA21-PHBV) had contact angles of 51.1° and 56.4° for water and diiodomethane, respectively. Weight loss of PAA21-PHBV in PBS at 180d was less than 6%. Subjected to 1.5SBF at 37 °C for 6d, PAA21-PHBV was covered by rounded mineral nodules (4˜10 μm in diameter), while few minerals could be seen on PHBV. Carboxylic groups functioned as nucleators would initiate mineralization to induce Ca-P coating process on PHBV surface.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · biodegradable polymer synthesis and properties · Orthopaedic implants and arthroplasty
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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