journal article·2025-03Open access

Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels

Xiaofeng Shi, Qianli Ma, Xinlin Jia, Zhaofan Wu, Chaohong Yu, Tian Gao, Wei Xu, Zhaonan Sun, Jingwei Zhang, Huanming Xiong, Yuanqing Mao

Small Structures· Volume 6· Issue 3

Abstract

In the complex process of wound healing, oleogels (OG) are suitable as the primary component of dressing materials, but they cannot meet the diverse requirements at different healing stages. In this study, a new kind of carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent hemostatic, antibacterial, anti‐inflammatory, and pro‐angiogenic properties and thus supports the various stages of wound healing effectively. Such CrCi‐CDs are incorporated into OG to produce a CrCi‐CD/OG composite material with enhanced multifunctional capabilities, significantly outperforming OG alone. Various experiments in vitro and in vivo confirm that the CrCi‐CDs/OG can rapidly achieve hemostasis at the initial stage of wound formation, subsequently inhibit bacterial proliferation and biofilm formation, improve the complex microenvironment surrounding the wound, and promote neovascularization, ultimately accelerating the wound repair.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Carbon and Quantum Dots Applications · Biochemical effects in animals

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Shanghai Key Laboratory of Orthopaedic Implants Department of Orthopedics Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine 639 Zhizaoju Road Shanghai 200011 P. R. China

Department of Chemistry Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Fudan University 2005 Songhu Road Shanghai 200433 P. R. China

Department of Plastic and Reconstructive Surgery Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine 639 Zhizaoju Road Shanghai 200011 P. R. China

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