DataVXSmall StructuresPaper
journal article·2021-07Open access

Three‐Dimensional Visualization of Subcellular Dynamics of Cancer Cell Destruction on Therapeutic Nanodrug Treatment

Sreejith Raveendran, Anindito Sen, Toru Maekawa, D. Sakthi Kumar

Small Structures· Volume 2· Issue 7
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Source abstract

Abstract

Multi-Modal Targeting Strategy for Breast Cancer In article number 2000145 by Sreejith Raveendran, D. Sakthi Kumar and co-workers, a multi-modal targeting strategy for breast cancer using combinatorial nanodrug complex is studied and ultra-structural visualization of subcellular targeting and multiple parallel damage caused to breast cancer cells are demonstrated using serial-block-face scanning electron microscopy. Mechanistic and conformational understanding of specific subcellular connections of novel smart nanocarriers with various intrinsic receptors are critical for the design and delivery of novel cancer therapeutics.
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Research context

Nanomaterials

OpenAlex topics: Computational Drug Discovery Methods · Graphene and Nanomaterials Applications · Cancer Research and Treatment

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Affiliations

Bio-Nano Electronics Research Centre Graduate School of Interdisciplinary New Science Toyo University 2100, Kujirai Kawagoe Saitama 350-8585 Japan

Nanoscale Research Facility Indian Institute of Technology Delhi Hauz Khas New Delhi 110016 India

Indian Institute of Technology, Delhi Hauz Khas New Delhi 110016 India

EM Business Unit JEOL Ltd. 13F, Ohtemachi Nomura Building, 2-1-1 Ohtemachi Chiyoda- Ku Tokyo Japan

Microscopy and Imaging Center Texas A&M University 301 Old Main Dr College Station TX 77843-2257 USA

References

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