Sulfinylation on Superoxide Dismutase 1 Cys111: Novel Mechanism for 1‐Nitropyrene to Promote Acute Reactive Oxygen Species Generation
Source abstract
Abstract
1-Nitropyrene In article number 2000123, Zongwei Cai and co-workers show that 1-nitropyrene inhibits superoxide dismutase 1 (SOD1) activity to increase intracellular reactive oxygen species (ROS) by forming cysteine sulfinylation on Cys111 of SOD1. Therefore, a novel mechanism of 1-nitropyrene-induced acute cytotoxicity and ROS production is proposed.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nitric Oxide and Endothelin Effects
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Affiliations
State Key Laboratory of Environmental and Biological Analysis Department of Chemistry Hong Kong Baptist University OEW 901, Oen Hall Building West Wing, Ho Sin Hang Campus, Kowloon Tong Hong Kong China
References
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