journal article·2020-07Open access

Micro‐/Nanomotors toward Biomedical Applications: The Recent Progress in Biocompatibility

Juanfeng Ou, Kun Liu, Jiamiao Jiang, Daniela A. Wilson, Lu Liu, Fei Wang, Shuanghu Wang, Yingfeng Tu, Fei Peng

Small· Volume 16· Issue 27

Abstract

Abstract Inspired by the highly versatile natural motors, artificial micro‐/nanomotors that can convert surrounding energies into mechanical motion and accomplish multiple tasks are devised. In the past few years, micro‐/nanomotors have demonstrated significant potential in biomedicine. However, the practical biomedical applications of these small‐scale devices are still at an infant stage. For successful bench‐to‐bed translation, biocompatibility of micro‐/nanomotor systems is the central issue to be considered. Herein, the recent progress in micro‐/nanomotors in biocompatibility is reviewed, with a special focus on their biomedical applications. Through close collaboration between researches in the nanoengineering, material chemistry, and biomedical fields, it is expected that a promising real‐world application platform based on micro‐/nanomotors will emerge in the near future.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Micro and Nano Robotics · Molecular Communication and Nanonetworks · Advanced Materials and Mechanics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Materials Science and Engineering Sun Yat‐Sen University Guangzhou 510275 China

School of Pharmaceutical Science Guangdong Provincial Key Laboratory of New Drug Screening Southern Medical University Guangzhou 510515 China

Institute for Molecules and Materials Radboud University Nijmegen 6525 AJ The Netherlands

Funding

National Natural Science Foundation of China

References (87)

Show source-provided references
1. 10.1039/C6CS00885B10.1039/C6CS00885B ↗
2. 10.1002/anie.20130164310.1002/anie.201301643 ↗
3. 10.1002/cphc.20140211110.1002/cphc.201402111 ↗
4. 10.1021/acsnano.5b0280710.1021/acsnano.5b02807 ↗
5. 10.1021/nn501407r10.1021/nn501407r ↗
6. 10.1016/j.biomaterials.2013.06.05510.1016/j.biomaterials.2013.06.055 ↗
7. 10.1002/adma.20150548710.1002/adma.201505487 ↗
8. 10.1002/adma.20167002910.1002/adma.201670029 ↗
9. 10.1021/ja104362r10.1021/ja104362r ↗
10. 10.1063/1.499344110.1063/1.4993441 ↗
11. 10.1038/nchem.128110.1038/nchem.1281 ↗
12. 10.1002/anie.20170327610.1002/anie.201703276 ↗
13. 10.1021/am502458h10.1021/am502458h ↗
14. 10.1021/nn400925q10.1021/nn400925q ↗
15. 10.1021/acsnano.6b0807910.1021/acsnano.6b08079 ↗
16. 10.1039/C8PY00559A10.1039/C8PY00559A ↗
17. 10.1016/j.neuron.2009.12.02610.1016/j.neuron.2009.12.026 ↗
18. Williams D. · Med. Device Technol. · 2006 · 17 · 9
19. 10.1002/jbm.b.3187710.1002/jbm.b.31877 ↗
20. Chen D. · Int. J. Mol. Med. · 2011 · 28 · 343
21. 10.1002/anie.20130091310.1002/anie.201300913 ↗
22. 10.1016/j.msec.2015.07.02210.1016/j.msec.2015.07.022 ↗
23. 10.1021/nn507097k10.1021/nn507097k ↗
24. 10.1039/C6NR09799E10.1039/C6NR09799E ↗
25. 10.1021/acsami.9b0376610.1021/acsami.9b03766 ↗
26. 10.1021/acsnano.6b0479510.1021/acsnano.6b04795 ↗
27. 10.1021/acsnano.8b0376010.1021/acsnano.8b03760 ↗
28. 10.1021/acs.chemrev.5b0004710.1021/acs.chemrev.5b00047 ↗
29. 10.1126/science.111439710.1126/science.1114397 ↗
30. 10.1021/acsnano.6b0625610.1021/acsnano.6b06256 ↗
31. 10.1021/nl404044d10.1021/nl404044d ↗
32. 10.1021/acsbiomaterials.7b0008610.1021/acsbiomaterials.7b00086 ↗
33. 10.1016/j.biomaterials.2007.03.01910.1016/j.biomaterials.2007.03.019 ↗
34. 10.1021/am507680u10.1021/am507680u ↗
35. Cao J. · Nanoscale · 2018 · 10 · 7425
36. 10.1021/acs.accounts.8b0020210.1021/acs.accounts.8b00202 ↗
37. 10.1002/adfm.20150105010.1002/adfm.201501050 ↗
38. Ávila B. E.‐F. · Sci. Robot. · 2018 · 3 · 485
39. 10.1039/C2NR32976J10.1039/C2NR32976J ↗
40. 10.1002/anie.20150418610.1002/anie.201504186 ↗
41. 10.1021/acs.nanolett.5b0393510.1021/acs.nanolett.5b03935 ↗
42. 10.1021/acsnano.5b0806710.1021/acsnano.5b08067 ↗
43. 10.1021/jacs.6b0685710.1021/jacs.6b06857 ↗
44. 10.1002/adfm.20170508610.1002/adfm.201705086 ↗
45. 10.1039/B715310D10.1039/B715310D ↗
46. 10.1021/acs.chemmater.5b0330310.1021/acs.chemmater.5b03303 ↗
47. 10.1021/acs.nanolett.5b0431810.1021/acs.nanolett.5b04318 ↗
48. 10.1002/anie.20190773310.1002/anie.201907733 ↗
49. 10.1021/nn303309z10.1021/nn303309z ↗
50. 10.1002/adfm.20150344110.1002/adfm.201503441 ↗
51. 10.1021/acs.nanolett.8b0505110.1021/acs.nanolett.8b05051 ↗
52. 10.1021/ja210874s10.1021/ja210874s ↗
53. 10.1002/anie.20161177410.1002/anie.201611774 ↗
54. 10.1038/s41467-017-00309-w10.1038/s41467-017-00309-w ↗
55. 10.1021/ja408954910.1021/ja4089549 ↗
56. 10.1002/smll.20160184610.1002/smll.201601846 ↗
57. 10.1002/adfm.20150224810.1002/adfm.201502248 ↗
58. 10.1021/nn301312z10.1021/nn301312z ↗
59. 10.1021/acs.accounts.8b0025410.1021/acs.accounts.8b00254 ↗
60. 10.1002/smll.20160397810.1002/smll.201603978 ↗
61. 10.1021/acsnano.7b0682410.1021/acsnano.7b06824 ↗
62. 10.1002/adma.20160325010.1002/adma.201603250 ↗
63. 10.1002/adma.20170197010.1002/adma.201701970 ↗
64. Liu L. · Chemistry · 2019 · 14 · 2325
65. 10.1063/1.307965510.1063/1.3079655 ↗
66. 10.1002/smll.20130353810.1002/smll.201303538 ↗
67. 10.1021/nl404815q10.1021/nl404815q ↗
68. 10.1021/nn502360t10.1021/nn502360t ↗
69. 10.1007/s10529-006-9219-z10.1007/s10529-006-9219-z ↗
70. 10.1002/bem.9910.1002/bem.99 ↗
71. 10.1002/anie.20120190210.1002/anie.201201902 ↗
72. 10.1021/acsnano.7b0192610.1021/acsnano.7b01926 ↗
73. 10.1002/anie.20171308210.1002/anie.201713082 ↗
74. 10.1002/smll.20140337210.1002/smll.201403372 ↗
75. 10.1002/anie.20180703310.1002/anie.201807033 ↗
76. 10.1021/jacs.6b0090210.1021/jacs.6b00902 ↗
77. 10.1007/s12274-016-1245-010.1007/s12274-016-1245-0 ↗
78. 10.1021/jacs.6b0986310.1021/jacs.6b09863 ↗
79. 10.1002/adfm.20170586210.1002/adfm.201705862 ↗
80. 10.1021/nn506200x10.1021/nn506200x ↗
81. 10.1039/C5NR03730A10.1039/C5NR03730A ↗
82. 10.1002/admi.20150050510.1002/admi.201500505 ↗
83. 10.1002/smll.20160367910.1002/smll.201603679 ↗
84. 10.1002/adma.20160630110.1002/adma.201606301 ↗
85. 10.1038/545406a10.1038/545406a ↗
86. 10.1002/adma.20130254410.1002/adma.201302544 ↗
87. 10.1021/acsnano.7b0639810.1021/acsnano.7b06398 ↗