Tumor‐Selective Nano‐Dispatcher Enforced Cancer Immunotherapeutic Effects via Regulating Lactate Metabolism and Activating Toll‐Like Receptors (Small 1/2025)
Source abstract
Abstract
Tumor-Selective Delivery In article number 2406870, Zhi-Yue Zhang and co-workers developed a nano-dispatcher to facilitate tumor-selective co-delivery of a monocarboxylate transporter 4 (MCT4) inhibitor and a TLR7/8 agonist. This approach enhances the immunotherapeutic effect by synergistically regulating lactate metabolism and activating dendritic cells.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Nanoparticle-Based Drug Delivery · Cancer, Stress, Anesthesia, and Immune Response
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
NMPA Key Laboratory for Technology Research and Evaluation of Drug Products Key Laboratory of Chemical Biology (Ministry of Education) Shandong Key Laboratory of Targeted Drug Delivery and Advanced Pharmaceutics Department of Pharmaceutics School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University Jinan Shandong 250012 China
References
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