journal article·2009-12-18Open access

Polymer‐Protected Sub‐2‐nm‐Nanogap Fabrication for Biological Sensing in Near‐Physiological Conditions

Huijuan Zhang, Robert J. Barsotti, Chee‐Leong Wong, Xuejia Xue, Xiaogang Liu, Francesco Stellacci, John T. L. Thong

Small· Volume 5· Issue 24

Abstract

Polymer-protected sub-2-nm nanogaps that are fabricated via a novel electrical stressing approach exhibit substantial ionic-current reduction in near-physiological conditions. These devices enable direct DNA detection in aqueous solution by utilizing assembly of oligonucleotide-modified gold nanoparticles to the nanogap (see image). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Molecular Junctions and Nanostructures · Nanopore and Nanochannel Transport Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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