Stem Cells: Hepatic Differentiation of Human Embryonic Stem Cells as Microscaled Multilayered Colonies Leading to Enhanced Homogeneity and Maturation (Small 21/2014)
Source abstract
Abstract
A versatile methodology for the derivation of 3D human hepatocyte aggregates with mature phenotype, homogenous morphology, and enhanced hepatic functions is introduced on page 4311 by Y. Du and co-workers. The continuous hepatic differentiation of pluripotent hESCs is realized in 3D multilayered microtissue format by a versatile off-the-shelf microstencil array. The 3D configuration for hepatic differentiation of hESCs represents a significant step toward the efficient generation of functional hepatocytes for regenerative medicine and drug discovery.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: 3D Printing in Biomedical Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Biofabrication Center Department of Mechanical Engineering Tsinghua University Beijing People's Republic of China
Department of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 China
Center of Stem Cell Biology & Regenerative Medicine Department of Basic Medical Sciences School of Medicine Tsinghua University Beijing 100084 China
Department of Medical Genome Sciences Graduate School of Frontier Sciences University of Tokyo Kashiwa, Chiba 277–8562 Japan
References
Reference metadata was not supplied for this record.