DataVXSmallPaper
journal article·2019-09Open access

Gene Therapy: Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework‐8 (ZIF‐8) (Small 36/2019)

Arpita Poddar, José J. Conesa, Kang Liang, Sudip Dhakal, Philipp Reineck, Gary Bryant, Eva Pereiro, Raffaele Ricco, Heinz Amenitsch, Christian Doonan, Xavier Mulet, Cara M. Doherty, Paolo Falcaro, Ravi Shukla

Small· Volume 15· Issue 36
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Source abstract

Abstract

Gene therapy utilizing non-viral delivery systems still lags behind its viral counterpart despite being the safer method. In article number 1902268, Ravi Shukla and co-workers explore the potential of metal–organic frameworks (MOFs) for gene delivery. The most fundamental aspect of DNA, its ability to translate into proteins, is investigated to determine the suitability of MOFs as delivery agents for gene therapy. The cover illustrates DNA embedded in the meshwork of ZIF-8. Kate Rowe is acknowledged for framework photograph.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Metal-Organic Frameworks: Synthesis and Applications

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Affiliations

Ian Potter NanoBiosensing Facility NanoBiotechnology Research Laboratory (NBRL) School of Science RMIT University Melbourne Victoria 3001 Australia

CSIRO Manufacturing Clayton Victoria 3168 Australia

ALBA Synchrotron Light Source MISTRAL Beamline – Experiments division. Cerdanyola del Vallès Barcelona 08290 Spain

School of Chemical Engineering and Graduate School of Biomedical Engineering University of New South Wales Library Road, Kensington Sydney NSW 2052 Australia

ARC Centre of Excellence for Nanoscale BioPhotonics School of Science RMIT University Melbourne Victoria 3001 Australia

Centre for Molecular and Nanoscale Physics School of Science RMIT University Melbourne Victoria 3001 Australia

Institute of Physical and Theoretical Chemistry Graz University of Technology 8010 Graz Austria

Institute of Inorganic Chemistry Graz University of Technology 8010 Graz Austria

Department of Chemistry and the Centre for Advanced Nanomaterials The University of Adelaide Adelaide South Australia 5005 Australia

References

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