Preparation of Neutron‐Activatable Holmium Nanoparticles for the Treatment of Ovarian Cancer Metastases
Source abstract
Abstract
Nanoparticles containing stable holmium ((165) Ho) are prepared by nanotemplate engineering and subsequently irradiated in a neutron flux to yield (166) Ho, a beta-emitting radiotherapeutic isotope. After intraperitoneal injection to mice bearing SKOV-3 ovarian tumors, significant tumor accumulation of the (166) Ho-nanoparticles is observed by SPECT imaging indicating the potential of these neutron activatable nanoparticles for internal radiation therapy of ovarian cancer metastases.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Radiation Therapy and Dosimetry · Boron Compounds in Chemistry · Nuclear Physics and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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