journal article·2014-01-15

Graphene Oxide: Photothermally Controlled Gene Delivery by Reduced Graphene Oxide–Polyethylenimine Nanocomposite (Small 1/2014)

Hyunwoo Kim, Won Jong Kim

Small· Volume 10· Issue 1
Publisher page

Abstract

An external-stimuli-triggered and spatially and temporally controlled gene delivery vehicle is constructed by H. Kim and W. J. Kim using a functionalized reduced graphene oxide (rGO)-based nanocomposite. Upon light irradiation, the vehicle generates local heat, causing the accelearated endosomal escape of polyplexes. This platform, described in detail on page 117, makes it possible to develop a photothermally controlled gene carrier with maximized therapeutic efficacy and high spatial/temporal control.
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Research context

OpenAlex topics: Graphene and Nanomaterials Applications

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References

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