Injectable hydrogel enabled by strained disulfide-thiol exchange and core-shell thiolated copolymer nanoparticles for efficient hydrophobic drug delivery
Bibliographic record
Abstract
No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.
Source: Not provided · Quality: missing
Research context
OpenAlex topics: Hydrogels: synthesis, properties, applications · Nanoplatforms for cancer theranostics · Supramolecular Self-Assembly in Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (62)
Show source-provided references
1. Zhang W, Wang R, Sun ZM, et al. Catechol-functionalized hydrogels: biomimetic design, adhesion mechanism, and biomedical applications. Chem Soc Rev, 2020, 49: 433–46410.1039/C9CS00285E ↗
2. Elias PZ, Liu GW, Wei H, et al. A functionalized, injectable hydrogel for localized drug delivery with tunable thermosensitivity: synthesis and characterization of physical and toxicological properties. J Control Release, 2015, 208: 76–8410.1016/j.jconrel.2015.03.003 ↗
3. Zhou X, He X, Shi K, et al. Injectable thermosensitive hydrogel containing erlotinib-loaded hollow mesoporous silica nanoparticles as a localized drug delivery system for NSCLC therapy. Adv Sci, 2020, 7: 200144210.1002/advs.202001442 ↗
4. Liao J, Wu Z, Qiu Y, et al. Injectable thermosensitive microsphere-hydrogel composite system: combined therapy of hepatocellular carcinoma by remodeling tumor immune microenvironment. Sci China Mater, 2024, 67: 3379–339110.1007/s40843-024-3001-3 ↗
5. Zhang G, Lv L, Deng Y, et al. Self-healing gelatin hydrogels cross-linked by combining multiple hydrogen bonding and ionic coordination. Macromol Rapid Commun, 2017, 38: 170001810.1002/marc.201700018 ↗
6. Li M, Zhang M, Liu Z, et al. Injectable and self-fused hydrogels with antifouling capability based on amino acid derivatives for postoperative anti-adhesion application. Sci China Mater, 2024, 67: 1521–153210.1007/s40843-023-2763-1 ↗
7. Wang H, Ji X, Li Y, et al. An ATP/ATPase responsive supramolecular fluorescent hydrogel constructed via electrostatic interactions between poly(sodium p-styrenesulfonate) and a tetraphenylethene derivative. J Mater Chem B, 2018, 6: 2728–273310.1039/C8TB00366A ↗
8. Osaki M, Yonei S, Ueda C, et al. Mechanical properties with respect to water content of host-guest hydrogels. Macromolecules, 2021, 54: 8067–807610.1021/acs.macromol.1c00970 ↗
9. Chen N, Wang H, Ling C, et al. Cellulose-based injectable hydrogel composite for pH-responsive and controllable drug delivery. Carbohydr Polym, 2019, 225: 11520710.1016/j.carbpol.2019.115207 ↗
10. Scheutz GM, Rowell JL, Ellison ST, et al. Harnessing strained disulfides for photocurable adaptable hydrogels. Macromolecules, 2020, 53: 4038–404610.1021/acs.macromol.0c00604 ↗
11. Wang L, Li B, Xu F, et al. Visual in vivo degradation of injectable hydrogel by real-time and non-invasive tracking using carbon nanodots as fluorescent indicator. Biomaterials, 2017, 145: 192–20610.1016/j.biomaterials.2017.08.039 ↗
12. Liu B, Zhang Z, Li B, et al. Acrylate monomer polymerization triggered by iron oxide magnetic nanoparticles and catechol containing microgels. Chem Eng J, 2023, 468: 14371610.1016/j.cej.2023.143716 ↗
13. Yu H, Wang Y, Yang H, et al. Injectable self-healing hydrogels formed via thiol/disulfide exchange of thiol functionalized F127 and dithiolane modified PEG. J Mater Chem B, 2017, 5: 4121–412710.1039/C7TB00746A ↗
14. Fairbanks BD, Singh SP, Bowman CN, et al. Photodegradable, photoadaptable hydrogels via radical-mediated disulfide fragmentation reaction. Macromolecules, 2011, 44: 2444–245010.1021/ma200202w ↗
15. Canadell J, Goossens H, Klumperman B. Self-healing materials based on disulfide links. Macromolecules, 2011, 44: 2536–254110.1021/ma2001492 ↗
16. Wiita AP, Ainavarapu SRK, Huang HH, et al. Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques. Proc Natl Acad Sci USA, 2006, 103: 7222–722710.1073/pnas.0511035103 ↗
17. Zhang X, Waymouth RM. 1,2-Dithiolane-derived dynamic, covalent materials: cooperative self-assembly and reversible cross-linking. J Am Chem Soc, 2017, 139: 3822–383310.1021/jacs.7b00039 ↗
18. Choh SY, Cross D, Wang C. Facile synthesis and characterization of disulfide-cross-linked hyaluronic acid hydrogels for protein delivery and cell encapsulation. Biomacromolecules, 2011, 12: 1126–113610.1021/bm101451k ↗
19. Chen M, Ren X, Dong L, et al. Preparation of dynamic covalently crosslinking keratin hydrogels based on thiol/disulfide bonds exchange strategy. Int J Biol Macromol, 2021, 182: 1259–126710.1016/j.ijbiomac.2021.05.057 ↗
20. Zhang Q, Shi CY, Qu DH, et al. Exploring a naturally tailored small molecule for stretchable, self-healing, and adhesive supramolecular polymers. Sci Adv, 2018, 4: eaat819210.1126/sciadv.aat8192 ↗
21. Shi CY, He DD, Zhang Q, et al. Robust and dynamic underwater adhesives enabled by catechol-functionalized poly(disulfides) network. Natl Sci Rev, 2023, 10: nwac13910.1093/nsr/nwac139 ↗
22. Shi CY, Zhang Q, Wang BS, et al. Intrinsically photopolymerizable dynamic polymers derived from a natural small molecule. ACS Appl Mater Interfaces, 2021, 13: 44860–4486710.1021/acsami.1c11679 ↗
23. Shi CY, Zhang XP, Zhang Q, et al. Closed-loop chemically recyclable covalent adaptive networks derived from elementary sulfur. Chem Sci, 2024, 15: 17460–1746810.1039/D4SC05031B ↗
24. Shi CY, Zhang Q, Wang BS, et al. Highly ordered supramolecular assembled networks tailored by bioinspired H-bonding confinement for recyclable ion-transport materials. CCS Chem, 2022, 5: 1422–143210.31635/ccschem.022.202202158 ↗
25. Huang P, Song H, Zhang Y, et al. FRET-enabled monitoring of the thermosensitive nanoscale assembly of polymeric micelles into macro-scale hydrogel and sequential cognate micelles release. Biomaterials, 2017, 145: 81–9110.1016/j.biomaterials.2017.07.012 ↗
26. Lou C, Tian X, Deng H, et al. Dialdehyde-β-cyclodextrin-crosslinked carboxymethyl chitosan hydrogel for drug release. Carbohydr Polym, 2020, 231: 11567810.1016/j.carbpol.2019.115678 ↗
27. Nasr FH, Khoee S, Dehghan MM, et al. Preparation and evaluation of contact lenses embedded with polycaprolactone-based nanoparticles for ocular drug delivery. Biomacromolecules, 2016, 17: 485–49510.1021/acs.biomac.5b01387 ↗
28. Presas E, Tovar S, Cunarro J, et al. Pre-clinical evaluation of a modified cyclodextrin-based nanoparticle for intestinal delivery of liraglutide. J Pharm Sci, 2021, 110: 292–30010.1016/j.xphs.2020.10.058 ↗
29. Mukalel AJ, Riley RS, Zhang R, et al. Nanoparticles for nucleic acid delivery: applications in cancer immunotherapy. Cancer Lett, 2019, 458: 102–11210.1016/j.canlet.2019.04.040 ↗
30. Wang Y, Zhang Z, Zheng C, et al. Multistage adaptive nanoparticle overcomes biological barriers for effective chemotherapy. Small, 2021, 17: 210057810.1002/smll.202100578 ↗
31. Chung HJ, Kim HJ, Hong ST. Tumor-specific delivery of a paclitaxel-loading HSA-haemin nanoparticle for cancer treatment. Nanomed-Nanotechnol Biol Med, 2020, 23: 10208910.1016/j.nano.2019.102089 ↗
32. Li Z, Ho W, Bai X, et al. Nanoparticle depots for controlled and sustained gene delivery. J Control Release, 2020, 322: 622–63110.1016/j.jconrel.2020.03.021 ↗
33. Zhang C, Zhao Y, Zhang E, et al. Co-delivery of paclitaxel and anti-VEGF siRNA by tripeptide lipid nanoparticle to enhance the anti-tumor activity for lung cancer therapy. Drug Deliver, 2020, 27: 1397–141110.1080/10717544.2020.1827085 ↗
34. Gao J, Li H, Yue P, et al. Multifunctional endogenous small molecule-derived polymer composite nanoparticles for the treatment of acute sepsis therapy. Sci China Mater, 2024, 67: 3885–389710.1007/s40843-024-3051-y ↗
35. Jahns M, Warwas DP, Krey MR, et al. Nanoporous hybrid core-shell nanoparticles for sequential release. J Mater Chem B, 2020, 8: 776–78610.1039/C9TB01846H ↗
36. Han R, Tang K, Hou Y, et al. Fabrication of core/shell/shell structure nanoparticle with anticancer drug and dual-photosensitizer co-loading for synergistic chemotherapy and photodynamic therapy. Microporous Mesoporous Mater, 2020, 297: 11004910.1016/j.micromeso.2020.110049 ↗
37. Sanchez A, Ovejero Paredes K, Ruiz-Cabello J, et al. Hybrid decorated core@shell janus nanoparticles as a flexible platform for targeted multimodal molecular bioimaging of cancer. ACS Appl Mater Interfaces, 2018, 10: 31032–3104310.1021/acsami.8b10452 ↗
38. Darwish MSA, Kim H, Lee H, et al. Engineering core-shell structures of magnetic ferrite nanoparticles for high hyperthermia performance. Nanomaterials, 2020, 10: 99110.3390/nano10050991 ↗
39. Liu H, Gong L, Lu S, et al. Three core-shell polymersomes for targeted doxorubicin delivery: sustained and acidic release. J Drug Deliver Sci Tech, 2021, 61: 10229310.1016/j.jddst.2020.102293 ↗
40. Varga N, Benkő M, Sebők D, et al. Mesoporous silica core-shell composite functionalized with polyelectrolytes for drug delivery. Microporous Mesoporous Mater, 2015, 213: 134–14110.1016/j.micromeso.2015.02.008 ↗
41. Bharti S, Kaur G, Gupta S, et al. Pegylated CdSe/ZnS core/shell nanoparticles for controlled drug release. Mater Sci Eng-B, 2019, 243: 115–12410.1016/j.mseb.2019.03.015 ↗
42. Pavan C, Santalucia R, Leinardi R, et al. Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles. Proc Natl Acad Sci USA, 2020, 117: 27836–2784610.1073/pnas.2008006117 ↗
43. Yalcin S. 27-Cytotoxicity and biocompatibility of advanced green materials. In: Ahmed S, ed. Applications of Advanced Green Materials. Cambridge: Woodhead Publishing, 2021. 705–72210.1016/B978-0-12-820484-9.00027-1 ↗
44. Solorio-Rodríguez A, Escamilla-Rivera V, Uribe-Ramirez M, et al. In vitro cytotoxicity study of superparamagnetic iron oxide and silica nanoparticles on pneumocyte organelles. Toxicol in Vitro, 2021, 72: 10507110.1016/j.tiv.2020.105071 ↗
45. Lu J, Zhu W, Dai L, et al. Fabrication of thermo- and pH-sensitive cellulose nanofibrils-reinforced hydrogel with biomass nanoparticles. Carbohydr Polym, 2019, 215: 289–29510.1016/j.carbpol.2019.03.100 ↗
46. Chen N, He X, Lu Q. Highly stretchable, repairable, and tough nano-composite hydrogel physically cross-linked by hydrophobic interactions and reinforced by surface-grafted hydrophobized cellulose nanocrystals. Macromol Rapid Commun, 2023, 44: 230005310.1002/marc.202300053 ↗
47. Hess A, Schmidt BVKJ, Schlaad H. Aminolysis induced functionalization of (RAFT) polymer-dithioester with thiols and disulfides. Polym Chem, 2020, 11: 7677–768410.1039/D0PY01365J ↗
48. Jung FA, Schart M, Bührend L, et al. Highly tunable nanostructures in a doubly pH-responsive pentablock terpolymer in solution and in thin films. Adv Funct Mater, 2021, 31: 210290510.1002/adfm.202102905 ↗
49. Dinari A, Abdollahi M, Sadeghizadeh M. Design and fabrication of dual responsive lignin-based nanogel via “grafting from” atom transfer radical polymerization for curcumin loading and release. Sci Rep, 2021, 11: 196210.1038/s41598-021-81393-3 ↗
50. Dutta A, Mahapatra M, Deb M, et al. Nonconjugated biocompatible macromolecular luminogens for sensing and removals of Fe(III) and Cu (II): DFT studies on selective coordination(s) and on-off sensing. Macromol Rapid Commun, 2021, 42: 200052210.1002/marc.202000522 ↗
51. Zhou Y, Wu P, Wu J, et al. Delivering nitric oxide with poly(n-butyl methacrylate) films doped with S-nitroso-N-acetylpenicillamine. Polymer, 2021, 228: 12394310.1016/j.polymer.2021.123943 ↗
52. Blyufer A, Lhamo S, Tam C, et al. Riluzole: a neuroprotective drug with potential as a novel anti-cancer agent (Review). Int J Oncol, 2021, 59: 9510.3892/ijo.2021.5275 ↗
53. Ilangovan G, Li H, Zweier JL, et al. In vivo measurement of tumor redox environment using EPR spectroscopy. Mol Cell Biochem, 2002, 234–235: 393–39810.1023/A:1015967305659 ↗
54. Kuppusamy P, Li H, Ilangovan G, et al. Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels1. Cancer Res, 2002, 62: 307–312
55. Laurence JS, Nelson BN, Ye Q, et al. Characterization of acid-neutralizing basic monomers in co-solvent systems by NMR. Int J Polym Mater Polym Biomater, 2014, 63: 361–36710.1080/00914037.2013.845192 ↗
56. Kates SA, Casale RA, Baguisi A, et al. Lipoic acid analogs with enhanced pharmacological activity. Bioorg Med Chem, 2014, 22: 505–51210.1016/j.bmc.2013.10.057 ↗
57. Cohn D, Sosnik A, Levy A. Improved reverse thermo-responsive polymeric systems. Biomaterials, 2003, 24: 3707–371410.1016/S0142-9612(03)00245-X ↗
58. Wei R, Cheng L, Zheng M, et al. Reduction-responsive disassemblable core-cross-linked micelles based on poly(ethylene glycol)- b-poly(N-2-hydroxypropyl methacrylamide)-lipoic acid conjugates for triggered intracellular anticancer drug release. Biomacromolecules, 2012, 13: 2429–243810.1021/bm3006819 ↗
59. Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer, 2003, 3: 330–33810.1038/nrc1074 ↗
60. Maderuelo C, Zarzuelo A, Lanao JM. Critical factors in the release of drugs from sustained release hydrophilic matrices. J Control Release, 2011, 154: 2–1910.1016/j.jconrel.2011.04.002 ↗
61. Fu Y, Kao WJ. Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems. Expert Opin Drug Deliver, 2010, 7: 429–44410.1517/17425241003602259 ↗
62. Yao H, Wei D, Che X, et al. Comb-like temperature-responsive polyhydroxyalkanoate-graft-poly(2-dimethylamino-ethylmethacrylate) for controllable protein adsorption. Polym Chem, 2016, 7: 5957–596510.1039/C6PY01235C ↗