Encapsulation of contrast imaging agents by polypropyleneimine‐based dendrimers
Source abstract
Abstract
Abstract Polypropyleneimines (PPIs) functionalized by glycerol‐based entities are prepared and characterized by diffusion‐ordered spectroscopy NMR. Showing low cytotoxicity against MRC5 fibroblasts, their encapsulation capacities of gadolinium complexes was evaluated. T1 measurements were performed to determine the relaxivity of the encapsulated gadopentetate dimeglumine (GdBOPTA) in dendrimers of fourth and fifth generation (GD‐PPI‐4 and GD‐PPI‐5). Comparison of the GdBOPTA relaxivity and the relaxivity of GdBOPTA‐loaded dendrimers showed a slight increase of the gadolinium chelate relaxivity. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 101A: 613–621, 2013.
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Research context
OpenAlex topics: Dendrimers and Hyperbranched Polymers · Lanthanide and Transition Metal Complexes · Advanced Polymer Synthesis and Characterization
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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