A Conceptual Overview of Surface-Enhanced Raman Scattering (SERS)
Source abstract
Abstract
This review briefly delves into the fundamental considerations of surface-enhanced Raman scattering (SERS). This technique combines Raman spectroscopy and nanotechnology with great potential for molecular fingerprint identification. SERS has been associated with remarkable characteristics: high-resolution detection for a small amount of sample, high sensitivity of Raman measurement, and more fluorescence quenching. The amplification of Raman signals can be enhanced by two different mechanisms: electromagnetic enhancement and charge transfer. The electromagnetic mechanism depends on localized surface plasmon resonance phenomena and the generation of hotspots. The charge transfer mechanism involves the electron transfer between the metal substrate and the molecule of interest. The sensing approach of SERS could be a label-free or label-based approach adsorbed on the substrate surface. The main challenge of the reproducibility of SERS substrates can be mitigated by development in nanotechnology. Surface-enhanced resonance Raman spectroscopy (SERRS), shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS), and tip-enhanced Raman spectroscopy (TERS) are other methods for generating enhancement of the Raman signal.
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Research context
OpenAlex topics: Gold and Silver Nanoparticles Synthesis and Applications · Advanced biosensing and bioanalysis techniques · Biosensors and Analytical Detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (60)
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1. Keating ME, Byrne HJ (2013) Raman spectroscopy in nanomedicine: current status and future perspectives. Nanomedicine 8:1335–1351. https://doi.org/10.2217/nnm.13.10810.2217/nnm.13.108 ↗
2. Kudelski A (2008) Analytical applications of Raman spectroscopy. Talanta 76(1):1–8. https://doi.org/10.1016/j.talanta.2008.02.04210.1016/j.talanta.2008.02.042 ↗
3. Paudel A, Raijada D, Rantanen J (2015) Raman spectroscopy in pharmaceutical product design. Adv Drug Deliv Rev 89:3–20. https://doi.org/10.1016/j.addr.2015.04.00310.1016/j.addr.2015.04.003 ↗
4. Hargreaves M (2021) Handheld Raman, SERS, and SORS. In: Crocombe R, Leary P, Kammrath B (eds) Portable spectroscopy and spectrometry. Wiley, Chichester, pp 347–37610.1002/9781119636489.ch38 ↗
5. Kumar S, Kumar P, Das A, Pathak CS (2020) Surface-enhanced Raman scattering: introduction and applications. In: Kahrizi M, Sohi PA (eds) Recent advances in nanophotonics-fundamentals and applications. IntechOpen, London, pp 1–24
6. Neuville DR, De Ligny D, Henderson GS (2014) Advances in Raman spectroscopy applied to earth and material sciences. Rev Mineral Geochem 78(1):509–541. https://doi.org/10.2138/rmg.2013.78.1310.2138/rmg.2013.78.13 ↗
7. John N, George S (2017) Raman spectroscopy. In: Thomas S, Thomas R, Zachariah AK, Mishra RK (eds) Spectroscopic methods for nanomaterials characterization, vol 2. Elsevier, Amsterdam, pp 95–12710.1016/B978-0-323-46140-5.00005-4 ↗
8. Eskandari V, Sahbafar H, Zeinalizad L, Hadi A (2022) A review of applications of surface-enhanced Raman spectroscopy laser for detection of biomaterials and a quick glance into its advances for COVID-19 investigations. ISSS J Micro Smart Syst 11:363–382. https://doi.org/10.1007/s41683-022-00103-x10.1007/s41683-022-00103-x ↗
9. Marks H, Schechinger M, Garza J, Locke A, Cote G (2017) Surface enhanced Raman spectroscopy (SERS) for in vitro diagnostic testing at the point of care. Nanophotonics 6(4):681–701. https://doi.org/10.1515/nanoph-2016-018010.1515/nanoph-2016-0180 ↗
10. Akanny E, Bonhomme A, Bessueille F, Bourgeois S, Bordes C (2021) Surface enhanced Raman spectroscopy for bacteria analysis: a review. Appl Spectrosc Rev 56(5):380–422. https://doi.org/10.1080/05704928.2020.179669810.1080/05704928.2020.1796698 ↗
11. Li L, Cao X, Zhang T, Wu Q, Xiang P, Shen C, Zou L, Li Q (2022) Recent developments in surface-enhanced Raman spectroscopy and its application in food analysis: alcoholic beverages as an example. Foods 11(14):2165. https://doi.org/10.3390/foods1114216510.3390/foods11142165 ↗
12. Zhu X, Xu T, Lin Q, Duan Y (2014) Technical development of Raman spectroscopy: from instrumental to advanced combined technologies. Appl Spectrosc Rev 49(1):64–82. https://doi.org/10.1080/05704928.2013.79880110.1080/05704928.2013.798801 ↗
13. Pan L, Zhang P, Daengngam C, Peng S, Chongcheawchamnan M (2022) A review of artificial intelligence methods combined with Raman spectroscopy to identify the composition of substances. J Raman Spectrosc 53(1):6–19. https://doi.org/10.1002/jrs.622510.1002/jrs.6225 ↗
14. Yaseen T, Sun DW, Cheng JH (2017) Raman imaging for food quality and safety evaluation: fundamentals and applications. Trends Food Sci Technol 62:177–189. https://doi.org/10.1016/j.tifs.2017.01.01210.1016/j.tifs.2017.01.012 ↗
15. Perez-Jimenez AI, Lyu D, Lu Z, Liu G, Ren B (2020) Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments. Chem Sci 11(18):4563–4577. https://doi.org/10.1039/D0SC00809E10.1039/D0SC00809E ↗
16. Li P, Long F, Chen W, Chen J, Chu PK, Wang H (2020) Fundamentals and applications of surface-enhanced Raman spectroscopy–based biosensors. Curr Opin Biomed Eng 13:51–59. https://doi.org/10.1016/j.cobme.2019.08.00810.1016/j.cobme.2019.08.008 ↗
17. Sur UK (2017) Surface-enhanced Raman scattering. In: Maaz K (ed) Raman spectroscopy and applications. Rijeka, IntechOpen, pp 293–31210.5772/66084 ↗
18. Zhang D, Liang P, Chen W, Tang Z, Li C, Xiao K, Jin S, Ni D, Yu Z (2021) Rapid field trace detection of pesticide residue in food based on surface-enhanced Raman spectroscopy. Microchim Acta 188(11):370. https://doi.org/10.1007/s00604-021-05025-310.1007/s00604-021-05025-3 ↗
19. Fleischmann M, Hendra PJ, McQuillan AJ (1974) Raman spectra of pyridine adsorbed at a silver electrode. Chem Phys Lett 26(2):163–166. https://doi.org/10.1016/0009-2614(74)85388-110.1016/0009-2614(74)85388-1 ↗
20. Jeanmaire DL, Van Duyne RP (1977) Surface Raman spectroelectrochemistry: part I. Heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrode. J Electroanal Chem Interface Electrochem 84(1):1–20. https://doi.org/10.1016/S0022-0728(77)80224-610.1016/S0022-0728(77)80224-6 ↗
21. Albrecht MG, Creighton JA (1977) Anomalously intense Raman spectra of pyridine at a silver electrode. J Am Chem Soc 99(15):5215–5217. https://doi.org/10.1021/ja00457a07110.1021/ja00457a071 ↗
22. Yamamoto YS, Itoh T (2016) Why and how do the shapes of surface-enhanced Raman scattering spectra change? Recent progress from mechanistic studies. J Raman Spectrosc 47(1):78–88. https://doi.org/10.1002/jrs.487410.1002/jrs.4874 ↗
23. McNay G, Eustace D, Smith WE, Faulds K, Graham D (2011) Surface-enhanced Raman scattering (SERS) and surface-enhanced resonance Raman scattering (SERRS): a review of applications. Appl Spectrosc 65(8):825–837. https://doi.org/10.1366/11-0636510.1366/11-06365 ↗
24. Kumar GP (2012) Plasmonic nano-architectures for surface enhanced Raman scattering: a review. J Nanophotonics 6(1):064503. https://doi.org/10.1117/1.JNP.6.06450310.1117/1.JNP.6.064503 ↗
25. Israelsen ND, Hanson C, Vargis E (2015) Nanoparticle properties and synthesis effects on surface-enhanced Raman scattering enhancement factor: an introduction. Sci World J 2015:1–12. https://doi.org/10.1155/2015/12458210.1155/2015/124582 ↗
26. Arockia Jency D, Umadevi M, Sathe GV (2015) SERS detection of polychlorinated biphenyls using β-cyclodextrin functionalized gold nanoparticles on agriculture land soil. J Raman Spectrosc 46(4):377–383. https://doi.org/10.1002/jrs.465410.1002/jrs.4654 ↗
27. Lombardi JR, Birke RL (2009) A unified view of surface-enhanced Raman scattering. Acc Chem Res 42(6):734–742. https://doi.org/10.1021/ar800249y10.1021/ar800249y ↗
28. Petry R, Schmitt M, Popp J (2003) Raman spectroscopy–a prospective tool in the life sciences. ChemPhysChem 4(1):14–30. https://doi.org/10.1002/cphc.20039000410.1002/cphc.200390004 ↗
29. Gauglitz G, Vo-Dinh T (2003) Handbook of spectroscopy. Wiley, Weinheim10.1002/3527602305 ↗
30. Majee BP, Mishra AK (2021) Fundamentals and applications of surface enhanced Raman spectroscopy. In: Singh DK, Pradhan M, Materny A (eds) Modern techniques of spectroscopy. Springer, Singapore, pp 185–20810.1007/978-981-33-6084-6_7 ↗
31. Mhlanga N, Tetyana P, Nyembe S, Sikhwivhilu L (2021) Application of Raman spectroscopy in biomedical diagnostics. In: Pathak CS, Kumar S (eds) Recent developments in atomic force microscopy and Raman spectroscopy for materials characterization. IntechOpen, London, pp 179–206
32. Chu X, Huang Y, Yun YH, Bian X (2022) Chemometric methods in analytical spectroscopy technology. Springer, Singapore10.1007/978-981-19-1625-0 ↗
33. Hossain MK, Ozaki Y (2009) Surface-enhanced Raman scattering: facts and inline trends. Curr Sci 97(2):192–201
34. Pilot R, Signorini R, Fabris L (2018) Surface-enhanced Raman spectroscopy: principles, substrates, and applications. In: Deepak FL (ed) Metal nanoparticles and clusters: advances in synthesis, properties and applications. Springer, Switzerland, pp 89–16410.1007/978-3-319-68053-8_4 ↗
35. Shi R, Liu X, Ying Y (2017) Facing challenges in real-life application of surface-enhanced Raman scattering: design and nanofabrication of surface-enhanced Raman scattering substrates for rapid field test of food contaminants. J Agric Food Chem 66(26):6525–6543. https://doi.org/10.1021/acs.jafc.7b0307510.1021/acs.jafc.7b03075 ↗
36. Bian J, Shu S, Li J, Huang C, Li YY, Zhang RQ (2015) Reproducible and recyclable SERS substrates: flower-like Ag structures with concave surfaces formed by electrodeposition. Appl Surf Sci 333:126–133. https://doi.org/10.1016/j.apsusc.2015.02.00710.1016/j.apsusc.2015.02.007 ↗
37. Zrimsek AB, Chiang N, Mattei M, Zaleski S, McAnally MO, Chapman CT, Henry AI, Schatz GC, Van Duyne RP (2017) Single-molecule chemistry with surface-and tip-enhanced Raman spectroscopy. Chem Rev 117(11):7583–7613. https://doi.org/10.1021/acs.chemrev.6b0055210.1021/acs.chemrev.6b00552 ↗
38. Castillo J, Rozo C, Wu K, Rindzevicius T, Boisen A, Castillo JJ (2021) Surface-enhanced Raman spectroscopy and density functional theory study of glyphosate and aminomethylphosphonic acid using silver capped silicon nanopillars. Univ Sci 26(1):51–66. https://doi.org/10.11144/Javeriana.SC26-1.srsa10.11144/Javeriana.SC26-1.srsa ↗
39. Haroon M, Abdulazeez I, Saleh TA, Al-Saadi AA (2020) SERS-based trace-level quantification of sulindac: spectroscopic and molecular modeling evaluation. J Mol Liq 312:113402. https://doi.org/10.1016/j.molliq.2020.11340210.1016/j.molliq.2020.113402 ↗
40. Grasseschi D, Toma HE (2017) The SERS effect in coordination chemistry. Coord Chem Rev 333:108–131. https://doi.org/10.1016/j.ccr.2016.11.01910.1016/j.ccr.2016.11.019 ↗
41. Lan L, Gao Y, Fan X, Li M, Hao Q, Qiu T (2021) The origin of ultrasensitive SERS sensing beyond plasmonics. Front Phys 16:1–26. https://doi.org/10.1007/s11467-021-1047-z10.1007/s11467-021-1047-z ↗
42. Gupta VP, Ozaki Y (2017) Molecular and laser spectroscopy: advances and applications, vol 2. Elsevier, Amsterdam
43. Muehlethaler C, Leona M, Lombardi JR (2016) Review of surface enhanced Raman scattering applications in forensic science. Anal Chem 88(1):152–169. https://doi.org/10.1021/acs.analchem.5b0413110.1021/acs.analchem.5b04131 ↗
44. Langer J, Jimenez de Aberasturi D, Aizpurua J, Alvarez-Puebla RA, Auguié B, Baumberg JJ, Bazan GC, Bell SE, Boisen A, Brolo AG, Choo J et al (2019) Present and future of surface-enhanced Raman scattering. ACS Nano 14(1):28–117. https://doi.org/10.1021/acsnano.9b0422410.1021/acsnano.9b04224 ↗
45. George SD (2020) Surface-enhanced Raman scattering substrates: fabrication, properties, and applications. In: Boddula R, Asiri AM (eds) Self-standing substrates. Springer, Switzerland, pp 83–11810.1007/978-3-030-29522-6_3 ↗
46. Lin T, Song YL, Liao J, Liu F, Zeng TT (2020) Applications of surface-enhanced Raman spectroscopy in detection fields. Nanomedicine 15(30):2971–2989. https://doi.org/10.2217/nnm-2020-036110.2217/nnm-2020-0361 ↗
47. Lin L, Bi X, Gu Y, Wang F, Ye J (2021) Surface-enhanced Raman scattering nanotags for bioimaging. J Appl Phys 129(19):191101. https://doi.org/10.1063/5.004757810.1063/5.0047578 ↗
48. Culha M, Cullum B, Lavrik N, Klutse CK (2012) Surface-enhanced Raman scattering as an emerging characterization and detection technique. J Nanotechnol 2012:1–15. https://doi.org/10.1155/2012/97138010.1155/2012/971380 ↗
49. Casadio F, Daher C, Bellot-Gurlet L (2017) Raman spectroscopy of cultural heritage materials: overview of applications and new frontiers in instrumentation, sampling modalities, and data processing. In: Mazzeo R (ed) Analytical chemistry for cultural heritage. Springer, Switzerland, pp 161–21110.1007/978-3-319-52804-5_5 ↗
50. Itoh T, Yamamoto YS, Ozaki Y (2017) Plasmon-enhanced spectroscopy of absorption and spontaneous emissions explained using cavity quantum optics. Chem Soc Rev 46(13):3904–3921. https://doi.org/10.1039/C7CS00155J10.1039/C7CS00155J ↗
51. Li GC, Zhang Q, Maier SA, Lei D (2018) Plasmonic particle-on-film nanocavities: a versatile platform for plasmon-enhanced spectroscopy and photochemistry. Nanophotonics 7(12):1865–1889. https://doi.org/10.1515/nanoph-2018-016210.1515/nanoph-2018-0162 ↗
52. Zhang Y, Dong ZC, Aizpurua J (2020) Influence of the chemical structure on molecular light emission in strongly localized plasmonic fields. J Phys Chem C 124(8):4674–4683. https://doi.org/10.1021/acs.jpcc.9b1025610.1021/acs.jpcc.9b10256 ↗
53. Wang AX, Kong X (2015) Review of recent progress of plasmonic materials and nano-structures for surface-enhanced Raman scattering. Mater 8(6):3024–3052. https://doi.org/10.3390/ma806302410.3390/ma8063024 ↗
54. Mousavi SM, Hashemi SA, Rahmanian V, Kalashgrani MY, Gholami A, Omidifar N, Chiang WH (2022) Highly sensitive flexible SERS-based sensing platform for detection of COVID-19. Biosensors 12(7):466. https://doi.org/10.3390/bios1207046610.3390/bios12070466 ↗
55. Lee HM, Jin SM, Kim HM, Suh YD (2013) Single-molecule surface-enhanced Raman spectroscopy: a perspective on the current status. Phys Chem Chem Phys 15(15):5276–5287. https://doi.org/10.1039/C3CP44463E10.1039/C3CP44463E ↗
56. Krajczewski J, Kudelski A (2019) Shell-isolated nanoparticle-enhanced Raman spectroscopy. Front Chem 7:410. https://doi.org/10.3389/fchem.2019.0041010.3389/fchem.2019.00410 ↗
57. Kumar N, Mignuzzi S, Su W, Roy D (2015) Tip-enhanced Raman spectroscopy: principles and applications. EPJ Tech Instrum 2(1):9. https://doi.org/10.1140/epjti/s40485-015-0019-510.1140/epjti/s40485-015-0019-5 ↗
58. Lucas M, Riedo E (2012) Invited review article: combining scanning probe microscopy with optical spectroscopy for applications in biology and materials science. Rev Sci Instrum 83(6):061101. https://doi.org/10.1063/1.472010210.1063/1.4720102 ↗
59. Mehtani D, Lee N, Hartschuh RD, Kisliuk A, Foster MD, Sokolov AP, Cajko F, Tsukerman I (2006) Optical properties and enhancement factors of the tips for apertureless near-field optics. J Opt A-Pure Appl Op 8(4):S183–S190. https://doi.org/10.1088/1464-4258/8/4/S1910.1088/1464-4258/8/4/S19 ↗
60. Sweetenham CS, Notingher I (2010) Raman spectroscopy methods for detecting and imaging supported lipid bilayers. Spectrosc 24(1–2):113–117. https://doi.org/10.3233/SPE-2010-042610.3233/SPE-2010-0426 ↗