Sensitivity Enhancement for Surface Plasmon Resonance Imaging Biosensor by Utilizing Gold–Silver Bimetallic Film Configuration
Source abstract
Abstract
Gold–silver bimetallic film configuration is brought forward to realize surface plasmon resonance imaging (SPRI) biosensor with the virtues of both high sensitivity and chemical stability. The theoretical calculation is adopted to optimize the thicknesses of the metal films, and bimetallic film configuration with high refractive index sensitivity and a good linearity between reflectivity and refractive index is presented. Then, the property of the detection system is discussed. The results show that in comparison to most commercial SPRI biosensors which use single gold films, the sensitivity and molecule detection ability of the gold–silver bimetallic film configuration can be improved to a great extent. For the substrate of BAK3 glass used in this paper, the sensitivity enhancement reaches as high as 80%, which makes it a much better choice for SPRI biosensing applications.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Plasmonic and Surface Plasmon Research · Gold and Silver Nanoparticles Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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