Plasmonic Nanoparticles: Enhancing Early Breast Cancer Detection Through Biosensors
Bibliographic record
Abstract
No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.
Source: Not provided · Quality: missing
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Gold and Silver Nanoparticles Synthesis and Applications · Biosensors and Analytical Detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Duffy MJ et al (2015) Biomarkers in breast cancer: where are we and where are we going? Adv Clin Chem 71:1–2310.1016/bs.acc.2015.05.001 ↗
2. Berdzuli N (2023) Breast cancer: from awareness to access, British Medical Journal Publishing Group.10.1136/bmj.p290 ↗
3. Siegel RL et al (2023) Cancer statistics. CA Cancer J Clin 73(1):17–48
4. Zubair M, Wang S, Ali N (2021) Advanced approaches to breast cancer classification and diagnosis. Front Pharmacol 11:63207910.3389/fphar.2020.632079 ↗
5. Liang Y et al (2021) Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer. Bioactive materials 6(2):433–44610.1016/j.bioactmat.2020.08.019 ↗
6. Tabatabaei MS, Ahmed M (2022) Enzyme-linked immunosorbent assay (ELISA). Cancer cell biology: Methods and protocols. Springer, pp 115–13410.1007/978-1-0716-2376-3_10 ↗
7. Pérez-Ruiz E et al (2018) Digital ELISA for the quantification of attomolar concentrations of Alzheimer’s disease biomarker protein Tau in biological samples. Anal Chim Acta 1015:74–8110.1016/j.aca.2018.02.011 ↗
8. Peng P et al (2022) Emerging ELISA derived technologies for in vitro diagnostics. TrAC, Trends Anal Chem 152:11660510.1016/j.trac.2022.116605 ↗
9. Malik S et al (2023) Nanomaterials-based biosensor and their applications: a review. Heliyon 9:e1992910.1016/j.heliyon.2023.e19929 ↗
10. Welch EC et al (2021) Advances in biosensors and diagnostic technologies using nanostructures and nanomaterials. Adv Func Mater 31(44):210412610.1002/adfm.202104126 ↗
11. Fathi F et al (2021) Investigation of optical and physical property in opal films prepared by colloidal and freeze-dried microspheres. Colloids Surf, A 611:12584210.1016/j.colsurfa.2020.125842 ↗
12. Dyussembayev K et al (2021) Biosensor technologies for early detection and quantification of plant pathogens. Front Chem 9:63624510.3389/fchem.2021.636245 ↗
13. Mishra M et al (2024) Recent advancements in the application of circulating tumor DNA as biomarkers for early detection of cancers. ACS Biomater Sci Eng 10(8):4740–475610.1021/acsbiomaterials.4c00606 ↗
14. Fathi F et al (2017) Early-stage detection of VE-cadherin during endothelial differentiation of human mesenchymal stem cells using SPR biosensor. Biosens Bioelectron 96:358–36610.1016/j.bios.2017.05.018 ↗
15. Li Y-B et al (2025) Ingenious microfluidic-microwave integrated biosensor for cell sorting and concentration detection of mixed white blood cells and yeasts solution. Chem Eng J 506:15974110.1016/j.cej.2025.159741 ↗
16. Abrao Nemeir I et al (2019) The advent of salivary breast cancer biomarker detection using affinity sensors. Sensors 19(10):237310.3390/s19102373 ↗
17. Eivazzadeh-Keihan R et al (2022) Applications of carbon-based conductive nanomaterials in biosensors. Chem Eng J 442:13618310.1016/j.cej.2022.136183 ↗
18. Rashidi M-R et al (2022) Investigation of optical images in inverse opal photonic crystal films for sensing applications; a non-destructive method. Opt Mater 125:11207210.1016/j.optmat.2022.112072 ↗
19. Kumar S et al (2023) Optically active nanomaterials and its biosensing applications—a review. Biosensors 13(1):8510.3390/bios13010085 ↗
20. Stephanie R et al (2021) Recent advances of bimetallic nanomaterials and its nanocomposites for biosensing applications. TrAC Trends Anal Chem 135:11615910.1016/j.trac.2020.116159 ↗
21. Manimekala T, Sivasubramanian R, Dharmalingam G (2022) Nanomaterial-based biosensors using field-effect transistors: a review. J Electron Mater 51(5):1950–197310.1007/s11664-022-09492-z ↗
22. Haghaei H et al (2019) Kinetic and thermodynamic study of beta-Boswellic acid interaction with Tau protein investigated by surface plasmon resonance and molecular modeling methods. BioImpacts BI 10(1):1710.15171/bi.2020.03 ↗
23. Ziai Y et al (2022) Smart plasmonic hydrogels based on gold and silver nanoparticles for biosensing application. Current Opin Biomed Eng 24:10041310.1016/j.cobme.2022.100413 ↗
24. Fathi F, Rashidi M-R, Omidi Y (2019) Ultra-sensitive detection by metal nanoparticles-mediated enhanced SPR biosensors. Talanta 192:118–12710.1016/j.talanta.2018.09.023 ↗
25. Chen J et al (2024) Design and optimization of a long-range surface plasmon resonance-based plasmonic SERS biosensor. Opt Mater 153:11561910.1016/j.optmat.2024.115619 ↗
26. De Silva Indrasekara AS (2021) Design criteria to fabricate plasmonic gold nanomaterials for surface-enhanced Raman scattering (SERS)-based biosensing. J Appl Phys 129(23).10.1063/5.0051795 ↗
27. Paramasivam G et al (2024) Nanomaterials for detection of biomolecules and delivering therapeutic agents in theragnosis: a review. Int J Biol Macromol 254:12790410.1016/j.ijbiomac.2023.127904 ↗
28. Sapsford KE et al (2013) Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology. Chem Rev 113(3):1904–207410.1021/cr300143v ↗
29. Sitia L et al (2022) HER-2-targeted nanoparticles for breast cancer diagnosis and treatment. Cancers 14(10):242410.3390/cancers14102424 ↗
30. García-Fernández D et al (2025) Tetrahedral DNA nanostructures, graphene and carbon nanodots-based electrochemiluminescent biosensor for BRCA1 gene mutation detection. Talanta 284:12718210.1016/j.talanta.2024.127182 ↗
31. Rakha EA, Reis-Filho JS, Ellis IO (2010) Combinatorial biomarker expression in breast cancer. Breast Cancer Res Treat 120:293–30810.1007/s10549-010-0746-x ↗
32. Nicolini A, Ferrari P, Duffy MJ (2018) Prognostic and predictive biomarkers in breast cancer: past, present and future. in Seminars in cancer biology. Elsevier.10.1016/j.semcancer.2017.08.010 ↗
33. Cole KD, He HJ, Wang L (2013) Breast cancer biomarker measurements and standards. PROTEOMICS Clin Appl 7(1–2):17–2910.1002/prca.201200075 ↗
34. Pepe MS et al (2001) Phases of biomarker development for early detection of cancer. J Natl Cancer Inst 93(14):1054–106110.1093/jnci/93.14.1054 ↗
35. Loke SY, Lee ASG (2018) The future of blood-based biomarkers for the early detection of breast cancer. Eur J Cancer 92:54–6810.1016/j.ejca.2017.12.025 ↗
36. Diansyah MN et al (2021) Early detection breast cancer: role of circulating plasma miRNA-21 expression as apotential screening biomarker. Turkish J Med Sci 51(2):562–56910.3906/sag-2005-138 ↗
37. Liu X et al (2021) Discovery and function exploration of microRNA-155 as a molecular biomarker for early detection of breast cancer. Breast Cancer 28:806–82110.1007/s12282-021-01215-2 ↗
38. Elsarraj HS et al (2012) Emerging functions of microRNA-146a/b in development and breast cancer: microRNA-146a/b in development and breast cancer. J Mammary Gland Biol Neoplasia 17:79–8710.1007/s10911-012-9240-x ↗
39. Barzaman K et al (2020) Breast cancer: biology, biomarkers, and treatments. Int Immunopharmacol 84:10653510.1016/j.intimp.2020.106535 ↗
40. Tarighati E, Keivan H, Mahani H (2023) A review of prognostic and predictive biomarkers in breast cancer. Clin Exp Med 23(1):1–16
41. Davey MG et al (2021) Ki-67 as a prognostic biomarker in invasive breast cancer. Cancers 13(17):445510.3390/cancers13174455 ↗
42. Raval A, Joshi J, Shah F (2022) Significance of metastamiR-10b in breast cancer therapeutics. J Egypt Natl Canc Inst 34(1):1910.1186/s43046-022-00120-9 ↗
43. Huang Q et al (2008) The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 10(2):202–21010.1038/ncb1681 ↗
44. Antolín S et al (2015) Circulating miR-200c and miR-141 and outcomes in patients with breast cancer. BMC Cancer 15:1–1510.1186/s12885-015-1238-5 ↗
45. Kim J, Munster PN (2025) Estrogens and breast cancer. Ann Oncol 36(2):134–14810.1016/j.annonc.2024.10.824 ↗
46. Li S et al (2022) Cancer risks associated with BRCA1 and BRCA2 pathogenic variants. J Clin Oncol 40(14):1529–154110.1200/JCO.21.02112 ↗
47. Sandberg D et al (2017) Intra-image referencing for simplified assessment of HER2-expression in breast cancer metastases using the Affibody molecule ABY-025 with PET and SPECT. Eur J Nucl Med Mol Imaging 44:1337–134610.1007/s00259-017-3650-3 ↗
48. Shimada H, Ochiai T, Nomura F (2003) Titration of serum p53 antibodies in 1085 patients with various types of malignant tumors: a multiinstitutional analysis by the Japan p53 Antibody Research Group. Cancer Interdiscip Int J Am Cancer Soc 97(3):682–689
49. O’Brien J et al (2018) Overview of microRNA biogenesis, mechanisms of actions, and circulation. Front Endocrinol 9:40210.3389/fendo.2018.00402 ↗
50. Guo Q, Yang C, Gao F (2022) The state of CD44 activation in cancer progression and therapeutic targeting. FEBS J 289(24):7970–798610.1111/febs.16179 ↗
51. Grunnet M, Sorensen J (2012) Carcinoembryonic antigen (CEA) as tumor marker in lung cancer. Lung Cancer 76(2):138–14310.1016/j.lungcan.2011.11.012 ↗
52. Duffy MJ et al (2000) CA 15–3: a prognostic marker in breast cancer. Int J Biol Markers 15(4):330–33310.1177/172460080001500410 ↗
53. Farzin L et al (2018) Recent advances in designing nanomaterial based biointerfaces for electrochemical biosensing cardiovascular biomarkers. J Pharm Biomed Anal 161:344–37610.1016/j.jpba.2018.08.060 ↗
54. Hammami I, Alabdallah NM (2021) Gold nanoparticles: synthesis properties and applications. J King Saud Univ-Sci 33(7):10156010.1016/j.jksus.2021.101560 ↗
55. Mikhailova EO (2021) Gold nanoparticles: biosynthesis and potential of biomedical application. J Funct Biomater 12(4):7010.3390/jfb12040070 ↗
56. Sargazi S et al (2022) Application of green gold nanoparticles in cancer therapy and diagnosis. Nanomaterials 12(7):110210.3390/nano12071102 ↗
57. Abdullah H, Uddin MS, Paul BK (2023) High-sensitivity gold-coated refractive index biosensor based on surface plasmon resonance. Plasmonics 18(6):2213–222310.1007/s11468-023-01890-1 ↗
58. Nejati K et al (2021) Biomedical applications of functionalized gold nanoparticles: a review. J Cluster Sci 33:1–1610.1007/s10876-020-01955-9 ↗
59. Rosero WAA et al (2024) Review of advances in coating and functionalization of gold nanoparticles: from theory to biomedical application. Pharmaceutics 16(2):25510.3390/pharmaceutics16020255 ↗
60. Fan J, Cheng Y, Sun M (2020) Functionalized gold nanoparticles: synthesis, properties and biomedical applications. Chem Rec 20(12):1474–150410.1002/tcr.202000087 ↗
61. Khurana K, Jaggi N (2021) Localized surface plasmonic properties of Au and Ag nanoparticles for sensors: a review. Plasmonics 16(4):981–99910.1007/s11468-021-01381-1 ↗
62. Johari-Ahar M et al (2023) Intercalation of anticancer drug mitoxantrone into DNA: studied by spectral and surface plasmon resonance methods. J Mol Struct 1274:13450910.1016/j.molstruc.2022.134509 ↗
63. Ranjbari F et al (2024) Kinetic and thermodynamic study of margatoxin peptide interaction with human serum albumin: studied by biophysical and docking methods. Int J Pept Res Ther 30(5):5210.1007/s10989-024-10633-7 ↗
64. Kumari A et al (2024) A review of surface plasmon resonance (SPR) technology in biosensing: innovations, applications and future trends. J Optics 1–910.1007/s12596-024-02265-3 ↗
65. Kim H-M et al (2022) High-performance biosensor using a sandwich assay via antibody-conjugated gold nanoparticles and fiber-optic localized surface plasmon resonance. Anal Chim Acta 1213:33996010.1016/j.aca.2022.339960 ↗
66. Balitskii O (2021) Recent energy targeted applications of localized surface plasmon resonance semiconductor nanocrystals: a mini-review. Materials Today Energy 20:10062910.1016/j.mtener.2020.100629 ↗
67. Kim DM et al (2021) Biosensing applications using nanostructure-based localized surface plasmon resonance sensors. Sensors 21(9):319110.3390/s21093191 ↗
68. Mayer KM, Hafner JH (2011) Localized surface plasmon resonance sensors. Chem Rev 111(6):3828–385710.1021/cr100313v ↗
69. Badilescu S et al (2020) Gold nano-island platforms for localized surface plasmon resonance sensing: a short review. Molecules 25(20):466110.3390/molecules25204661 ↗
70. Zhao J et al (2021) Localized surface plasmon resonance for enhanced electrocatalysis. Chem Soc Rev 50(21):12070–1209710.1039/D1CS00237F ↗
71. Bonyár A (2020) Label-free nucleic acid biosensing using nanomaterial-based localized surface plasmon resonance imaging: a review. ACS Applied Nano Materials 3(9):8506–852110.1021/acsanm.0c01457 ↗
72. Mukherjee A et al (2023) Three-dimensional (3D) surface-enhanced Raman spectroscopy (SERS) substrates: fabrication and SERS applications. J Phys Chem C 127(28):13689–1369810.1021/acs.jpcc.3c02410 ↗
73. Eskandari V et al (2023) Surface-enhanced Raman scattering (SERS) filter paper substrates decorated with silver nanoparticles for the detection of molecular vibrations of Acyclovir drug. Spectrochim Acta Part A Mol Biomol Spectrosc 298:12276210.1016/j.saa.2023.122762 ↗
74. Zhao Q et al (2022) All-hot-spot bulk surface-enhanced Raman scattering (SERS) substrates: attomolar detection of adsorbates with designer plasmonic nanoparticles. J Am Chem Soc 144(29):13285–1329310.1021/jacs.2c04514 ↗
75. Mehmandoust S, Eskandari V, Karooby E (2024) A review of fabrication of DNA origami plasmonic structures for the development of surface-enhanced Raman scattering (SERS) platforms. Plasmonics 19(3):1131–114310.1007/s11468-023-02064-9 ↗
76. Karnwal A et al (2024) Gold nanoparticles in nanobiotechnology: from synthesis to biosensing applications. ACS Omega 9(28):29966–2998210.1021/acsomega.3c10352 ↗
77. Siciliano G et al (2024) Beyond traditional biosensors: recent advances in gold nanoparticles modified electrodes for biosensing applications. Talanta 268:12528010.1016/j.talanta.2023.125280 ↗
78. Dias D et al (2024) A study of the stability and repeatability of U-shaped plastic optical fibers functionalized with gold nanoparticles for refractive index measurement. Opt Mater 150:11526510.1016/j.optmat.2024.115265 ↗
79. Khosroshahi ME, Chabok R, Chung N (2023) Glass-based nanobiosensor immobilized with oriented antibody-conjugated gold nanourchin for targeted detection of breast cancer biomarker in serum using FT-NIR and SERS. Plasmonics 18(6):2155–217610.1007/s11468-023-01929-3 ↗
80. Kumar N et al (2023) Immunosensor for breast cancer CD44 biomarker detection based on exfoliated graphene quantum dots integrated gold nanoparticles. Hybrid Advances 3:10006510.1016/j.hybadv.2023.100065 ↗
81. Khosroshahi ME et al (2024) Fabrication of and characterization of directional antibody-conjugated gold nanourchin colloid and effect of laser polarization on SERS detection of breast cancer biomarker in serum. Colloids Surf, A 694:13403510.1016/j.colsurfa.2024.134035 ↗
82. Weihs F et al (2021) Resonance energy transfer-based biosensors for point-of-need diagnosis—progress and perspectives. Sensors 21(2):66010.3390/s21020660 ↗
83. Dargah MM et al (2024) Triplex hairpin oligosensor for ultrasensitive determination of miRNA-155 as a cancer marker using Si quantum dots and Au nanoparticles. Spectrochim Acta Part A Mol Biomol Spectrosc 322:12475010.1016/j.saa.2024.124750 ↗
84. Olorundare FO et al (2024) A nanodiamond/gold nanoparticle-based electrochemical immunosensor for the detection of HER 2 cancer biomarker. Biosens Bioelectronics: X 18:100483
85. Rahmidar L et al (2024) Label-free and early detection of HER2 breast cancer biomarker based on UiO-66-NH2 modified gold chip (Au/UiO-66-NH2) using surface plasmon resonance technique. Microchem J 199:10996310.1016/j.microc.2024.109963 ↗
86. Baker AN et al (2022) Glycosylated gold nanoparticles in point of care diagnostics: from aggregation to lateral flow. Chem Soc Rev 51(16):7238–725910.1039/D2CS00267A ↗
87. Wang C et al (2023) A portable colorimetric point-of-care testing platform for microRNA detection based on programmable entropy-driven dynamic DNA network modulated DNA-gold nanoparticle hybrid hydrogel film. Biosens Bioelectron 225:11507310.1016/j.bios.2023.115073 ↗
88. Larraga-Urdaz AL et al (2024) A plasmonic MNAzyme signal amplification strategy for quantification of miRNA-4739 breast cancer biomarker. Anal Chim Acta 1285:34199910.1016/j.aca.2023.341999 ↗
89. Zhang M et al (2023) One-step multiplex analysis of breast cancer exosomes using an electrochemical strategy assisted by gold nanoparticles. Anal Chim Acta 1254:34113010.1016/j.aca.2023.341130 ↗
90. Li L et al (2023) Visual and electrochemical determination of breast cancer marker CA15-3 based on etching of Au@ Ag core/shell nanoparticles. Int J Electrochem Sci 18(5):10012310.1016/j.ijoes.2023.100123 ↗
91. Kailemia MJ, Park D, Lebrilla CB (2017) Glycans and glycoproteins as specific biomarkers for cancer. Anal Bioanal Chem 409:395–41010.1007/s00216-016-9880-6 ↗
92. Ratan C et al (2021) MUC glycoproteins: potential biomarkers and molecular targets for cancer therapy. Curr Cancer Drug Targets 21(2):132–15210.2174/1568009620666201116113334 ↗
93. Wu X et al (2024) Aptamer biorecognition and gold nanoshell-mediated fluorescence quenching for glycoprotein analysis and breast cancer diagnosis. Microchem J 201:11071910.1016/j.microc.2024.110719 ↗
94. Kim S et al (2020) Label-free surface-enhanced Raman spectroscopy biosensor for on-site breast cancer detection using human tears. ACS Appl Mater Interfaces 12(7):7897–790410.1021/acsami.9b19421 ↗
95. Guo W et al (2024) Comparative study of optical fiber immunosensors based on traditional antibody or nanobody for detecting HER2. Talanta 277:12631710.1016/j.talanta.2024.126317 ↗
96. Shekari Z, Zare HR, Falahati A (2021) Dual assaying of breast cancer biomarkers by using a sandwich–type electrochemical aptasensor based on a gold nanoparticles–3D graphene hydrogel nanocomposite and redox probes labeled aptamers. Sens Actuators B Chem 332:12951510.1016/j.snb.2021.129515 ↗
97. Makableh Y et al (2023) Enhanced response and selective gold nanoparticles/carbon nanotubes biosensor for the early detection of HER2 biomarker. Sens Actuators Rep 5:10015810.1016/j.snr.2023.100158 ↗
98. Bhatia M et al (2016) The thioredoxin system in breast cancer cell invasion and migration. Redox Biol 8:68–7810.1016/j.redox.2015.12.004 ↗
99. Shin J et al (2024) Evaluation of enzyme-mimetic nanoparticle employed lateral flow immunoassay device for breast cancer diagnosis by detecting thioredoxin 1 in actual human serum. Microchemical Journal 203:11091910.1016/j.microc.2024.110919 ↗
100. Hou Z et al (2022) Direct ultrasensitive electrochemical detection of breast cancer biomarker-miRNA-21 employing an aptasensor based on a microgel nanoparticle composite. Sens Actuators B Chem 367:13206710.1016/j.snb.2022.132067 ↗