Sensitive Hemoglobin Concentration Sensor Based on Graphene-Plasmonic Nano-structures
Source abstract
Abstract
In this paper, half-cylindrical-shaped rods are arranged in a row in order to form hemoglobin concentration sensors. The proposed structures can effectively detect hemoglobin concentrations in blood samples. Five individual structures based on graphene-plasmonic combinations are proposed and investigated. The proposed structures are made of different layers of Au, Ag, SiO2, and graphene. Different plates and cylindrical-shaped graphene layers are introduced in the structures to improve the functionality (absorption peak value and wavelength) of the absorber (sensor). Adding more Au layers strengthens the confinement of the incident electromagnetic waves and improves the absorption factor. Also, in the proposed structures, for improving the results, the effects of the chemical potential of graphene layers and "G" (graphene layer thicknesses) on the absorption peak and wavelength are considered. The final suggested structure indicates unity absorption peak and thus can be utilized in wide ranges of applications. As a refractive index bio-sensor, the structure is considered for detecting hemoglobin concentrations in blood samples which indicates a reasonable sensitivity factor of 570 nm/RIU.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Plasmonic and Surface Plasmon Research · Gold and Silver Nanoparticles Synthesis and Applications · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (42)
Show source-provided references
1. El barghouti M et al (2020) Design of silver nanoparticles with graphene coatings layers used for LSPR biosensor applications. Vacuum 180:10949710.1016/j.vacuum.2020.109497 ↗
2. Singh P (2017) Surface plasmon resonance: a boon for viral diagnostics, In book: Reference Module in Life Sciences10.1016/B978-0-12-809633-8.12245-9 ↗
3. Hajati Y (2020) Tunable broadband multiresonance graphene terahertz sensor. Opt Mater 101:109725. https://doi.org/10.1016/j.optmat.2020.10972510.1016/j.optmat.2020.109725 ↗
4. Chau YF et al (2009) Surface plasmon effects excitation from three-pair arrays of silver-shell nanocylinders. Phys Plasmas 16:02230310.1063/1.3068469 ↗
5. Ho YZ et al (2012) Tunable plasmonic resonance arising from broken-symmetric silver nanobeads with dielectric cores. J Opt 14:11401010.1088/2040-8978/14/11/114010 ↗
6. Chau YF (2009) Surface plasmon effects excited by the dielectric hole in a silver-shell nanospherical pair. Plasmonics 4:253–25910.1007/s11468-009-9100-8 ↗
7. Emami F et al (2019) Plasmonic multi channel filter based on split ring resonators: application to photothermal therapy. Photonics Nanostructures: Fundam Appl 33:21–2810.1016/j.photonics.2018.11.006 ↗
8. Sharma AK, Gupta J (2018) Graphene based chalcogenide fiber-optic evanescent wave sensor for detection of hemoglobin in human blood. Opt Fiber Technol 41:125–13010.1016/j.yofte.2018.01.012 ↗
9. Chau YF et al (2020) Perfect dual-band absorber based on plasmonic effect with the cross-hair/nanorod combination. Nanomaterials 10:49310.3390/nano10030493 ↗
10. Chau YF et al (2018) Plasmonic effects in composite metal nanostructures for sensing applications. J Nanopart Res 20:19010.1007/s11051-018-4293-4 ↗
11. Chau YF et al (2020) Enhancing plasmonic effect in periodic nanometal square prisms with fences and cavities for refractive index and temperature sensing applications. J Nanopart Res 22:29710.1007/s11051-020-05023-1 ↗
12. Panda A et al (2020) Performance analysis of graphene-based surface plasmon resonance biosensor for blood glucose and gas detection. Appl Phys A 126. https://doi.org/10.1007/s00339-020-3328-810.1007/s00339-020-3328-8 ↗
13. Wang X et al (2014) Fabrication techniques of graphene nanostructures. Nanofabrication and its application in renewable energy pp 1–30. https://doi.org/10.1039/9781782623380-0000110.1039/9781782623380-00001 ↗
14. Bonaccorso F et al (2012) Production and processing of graphene and 2d crystals. Mater Today 15:564–58910.1016/S1369-7021(13)70014-2 ↗
15. Rahman MS et al (2020) Enhanced performance of SnSe-graphene hybrid photonic surface plasmon refractive sensor for biosensing applications. Photonics Nanostructures: Fundam Appl 39:100779. https://doi.org/10.1016/j.photonics.2020.10077910.1016/j.photonics.2020.100779 ↗
16. Emami F et al (2021) Graphene-metal nanostructure as opto-fluid sensor. Optik Available online 10 March 166713. https://doi.org/10.1016/j.ijleo.2021.16671310.1016/j.ijleo.2021.166713 ↗
17. Chau YF et al (2009) Three-dimensional analysis of surface plasmon resonance modes on a gold nanorod. Appl Opt 48:617–62210.1364/AO.48.000617 ↗
18. Chau YF et al (2016) Tailoring surface plasmon resonance and dipole cavity plasmon modes of scattering cross section spectra on the single solid-gold/gold-shell nanorod. J Appl Phys 120:09311010.1063/1.4962175 ↗
19. Chau YF et al (2018) Depolying tunable metal-shell/dielectric core nanorod arrays as the virtually perfect absorber in the near-infrared regime. ACS Omega 3:7508–751610.1021/acsomega.8b00362 ↗
20. Sengupta J et al (2021) Graphene-based field-effect transistor biosensors for the rapid detection and analysis of viruses: a perspective in view of COVID-19. Carbon Trends 2:100011. https://doi.org/10.1016/j.cartre.2020.10001110.1016/j.cartre.2020.100011 ↗
21. El barghouti M., et al (2020) Design of silver nanoparticles with graphene coatings layers used for LSPR biosensor applications. Vacuum 180:109497. https://doi.org/10.1016/j.vacuum.2020.10949710.1016/j.vacuum.2020.109497 ↗
22. Heidarzadeh H (2020) Analysis and simulation of a plasmonic biosensor for hemoglobin concentration detection using noble metal nano-particles resonances. Opt Commun 459:124940. https://doi.org/10.1016/j.optcom.2019.12494010.1016/j.optcom.2019.124940 ↗
23. Vermisoglou E (2020) Human virus detection with graphene-based materials. Biosens Bioelectron 166:112436. https://doi.org/10.1016/j.bios.2020.11243610.1016/j.bios.2020.112436 ↗
24. Sadeghi Z et al (2020) Highly sensitive Mid-infrared SPR biosensor for a wide range of bio-molecules and biological cells based on graphene-gold grating. Physica E: Low-dimens Syst and Nanostruct 119:114005. https://doi.org/10.1016/j.physe.2020.11400510.1016/j.physe.2020.114005 ↗
25. Chau YF et al (2019) Strong and tunable plasmonic field coupling and enhancement generating from the protruded metal nanorods and dielectric cores. Results Phys 13:10229010.1016/j.rinp.2019.102290 ↗
26. Chau YF et al (2020) Ultrawide bandgap and high sensitivity of a plasmonic metal-insulator-metal waveguide filter with cavity and baffles. Nanomater 10:203010.3390/nano10102030 ↗
27. Li H et al (2019) Dual-band, polarization-insensitive metamaterial perfect absorber based on monolayer graphene in the mid-infrared range. Results Phys 13:102313. https://doi.org/10.1016/j.rinp.2019.10231310.1016/j.rinp.2019.102313 ↗
28. Hanson GW (2008) Dyadic green's functions and guided surface waves for a surface conductivity model of graphene. J Appl Phys 103. https://doi.org/10.1063/1.289145210.1063/1.2891452 ↗
29. Emami F et al (2018) Design and simulation of a novel nano plasmonic split ring resonator filter. J Electromagn Waves Appl 32:1925–193810.1080/09205071.2018.1482240 ↗
30. Emami F, Rafiee E, Negahdari R (2019) Design and analysis of the novel plasmonic split ring resonator power splitter appropriate for photonic integrated circuits. J Optoelectron Adv Mater 21:163–170
31. Emami F et al (2019) Realization of all‑optical plasmonic MIM split square ring resonator switch. Opt Quantum Electron 5110.1007/s11082-019-1924-7 ↗
32. Zare MS et al (2019) A strong controllable absorber using graphene metal Nanostructure. J Mod Opt 66:7–1610.1080/09500340.2018.1510055 ↗
33. Xu Z et al (2018) Design of a tunable ultra-broadband terahertz absorber based on multiple layers of graphene ribbons. Nanoscale Res Lett 1310.1186/s11671-018-2552-z ↗
34. Zhang J et al (2018) A dual-band tunable metamaterial near-unity absorber composed of periodic cross and disk graphene arrays. IEEE Photonics J 1010.1109/JPHOT.2018.2815685 ↗
35. Liu C et al (2018) Symmetrical dual D-shape photonic crystal fibers for surface plasmon resonance sensing. Opt Express 2610.1364/OE.26.009039 ↗
36. Sharma AK et al (2018) Graphene based chalcogenide fiber-optic evanescent wave sensor for detection of hemoglobin in human blood. Opt Fiber Technol 41:125–13010.1016/j.yofte.2018.01.012 ↗
37. Chen X et al (2018) Surface plasmon resonance sensor based on a novel D-shaped photonic crystal fiber for low refractive index detection. IEEE Photonics J 1010.1109/JPHOT.2018.2790424 ↗
38. Vahed H et al (2019) Sensitivity enhancement of SPR optical biosensor based on Graphene–MoS2 structure with nanocomposite layer. Opt Mater 88:161–16610.1016/j.optmat.2018.11.034 ↗
39. Dey B et al (2021) Numerical design of high-performance WS2/metal/WS2/graphene heterostructure based surface plasmon resonance refractive index sensor. Results Phys 23:10402110.1016/j.rinp.2021.104021 ↗
40. Sahraeian S et al (2021) Tunable terahertz absorber based on graphene-metal nanostructure as opto-fluid Sensor. Optik 242:16671310.1016/j.ijleo.2021.166713 ↗
41. Pal A et al (2021) A theoretical analysis on sensitivity improvement of an SPR refractive index sensor with graphene and barium titanate nanosheets. Optik 231:16637810.1016/j.ijleo.2021.166378 ↗
42. Ye Y et al (2019) Highly sensitive and tunable terahertz biosensor based on optical Tamm states in graphene-based Bragg reflector. Results Phys 15:10277910.1016/j.rinp.2019.102779 ↗