journal article·2025-08

Review of biodegradable Mg-based bulk metallic glass composites for orthopedic fixation implant applications: Mechanical properties, degradation behaviors, biocompatibility, and the other biological responses

Pei-Chun Wong, J.S.C. Jang

Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Magnesium Alloys: Properties and Applications · Aluminum Alloys Composites Properties · Bone Tissue Engineering Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (90)

Show source-provided references
1. Biodegradable magnesium-based biomaterials: an overview of challenges and opportunities10.1002/mco2.59 ↗
2. Magnesium-based biomaterials as emerging agents for bone repair and regeneration: from mechanism to application10.1016/j.jma.2021.03.004 ↗
3. Advances in magnesium-based biomaterials: strategies for enhanced corrosion resistance, mechanical performance, and biocompatibility
4. Magnesium-based biodegradable alloy materials for bone healing application10.1155/2024/1325004 ↗
5. Margareta Nordin · 2012
6. A brief review of bone cell function and importance10.3390/cells12212576 ↗
7. A biomimetic in situ mineralization ECM composite scaffold to promote endogenous bone regeneration10.1016/j.colsurfb.2023.113587 ↗
8. Engineering large-scale self-mineralizing bone organoids with bone matrix-inspired hydroxyapatite hybrid bioinks
9. Advances in osseointegration of biomimetic mineralized collagen and inorganic metal elements of natural bone for bone repair10.1093/rb/rbad030 ↗
10. Bone stress injuries10.1038/s41572-022-00352-y ↗
11. Biomaterials and nanomedicine for bone regeneration: progress and future prospects
12. Alendronate prolongs the reversal-resorption phase in human cortical bone remodeling10.1016/j.bone.2022.116419 ↗
13. InSpace implant compared with partial repair for the treatment of Full-Thickness massive rotator cuff tears: a multicenter, single-blinded, randomized controlled trial10.2106/JBJS.21.00667 ↗
14. Degradable magnesium implants inhibit gallbladder cancer10.1016/j.actbio.2021.04.051 ↗
15. Retrospective analysis of dental implant fracture following loading: a retrospective clinical study10.1016/j.prosdent.2025.02.046 ↗
16. The potential for foreign body reaction of implanted poly-L-lactic acid: a systematic review10.3390/polym16060817 ↗
17. A hydrogel containing Mg2+ with improved osteogenesis, enhanced endochondral ossification, and modulated inflammation for bone-repair applications10.1016/j.cej.2024.152762 ↗
18. Early immunomodulation by magnesium ion: catalyst for superior osteogenesis
19. 3D-printed magnesium/strontium-co-doped calcium silicate scaffolds promote angiogenesis and bone regeneration through synergistic bioactive ion stimulation10.1186/s13036-025-00528-6 ↗
20. In vivo corrosion of four magnesium alloys and the associated bone response10.1016/j.biomaterials.2004.09.049 ↗
21. Pitting corrosion of a rare earth mg alloy GW9310.1016/j.jmst.2017.01.014 ↗
22. Monetite and brushite coated magnesium: in vivo and in vitro models for degradation analysis10.1007/s10856-013-5059-2 ↗
23. Progress, applications, and challenges of amorphous alloys: a critical review10.3390/inorganics12090232 ↗
24. Exploring the impact of cooling rates and pressure on fragility and structural transformations in iron monatomic metallic glasses: insights from molecular dynamics simulations10.1016/j.jnoncrysol.2023.122623 ↗
25. Mechanically-Induced Solid-State reaction for fabrication of soft magnetic (Co(75)Ti(25))(100-x)B(x) (x: 2, 5, 10, 15, 20, 25 at%) metallic glassy nanopowders10.3390/molecules25153338 ↗
26. Coherent Atomic-Scale ripples on metallic glasses patterned by low-energy ion irradiation for large-area surface structuring10.1021/acsanm.0c02548 ↗
27. High-entropy metallic glasses10.1007/s11837-014-1002-3 ↗
28. Altering the metastable wear performance of metallic glasses via mixing entropy regulation
29. Du · Encycl. Mater. Met. Alloy. · 2022 · 318
30. Immunohistochemical evaluation: the effects of propolis on osseointegration of dental implants in rabbit's tibia
31. Poisson's ratio and plasticity in CuZrAl bulk metallic glasses10.1016/j.msea.2007.07.062 ↗
32. Enhanced mechanical properties of MgZnCa bulk metallic glass composites with Ti-particle dispersion10.3390/met6050116 ↗
33. Three-dimensional microstructure modeling of particulate composites using statistical synthetic structure and its thermo-mechanical finite element analysis10.1016/j.commatsci.2016.09.033 ↗
34. Analysis of the stress states and interface damage in a particle reinforced composite based on a micromodel using cohesive elements10.1016/j.msea.2013.09.097 ↗
35. Degradation behavior and mechanical strength of Mg-Zn-Ca bulk metallic glass composites with ti particles as biodegradable materials10.1016/j.jallcom.2017.01.010 ↗
36. Biocompatibility and osteogenic capacity of Mg-Zn-Ca bulk metallic glass for rabbit Tendon-Bone interference fixation10.3390/ijms20092191 ↗
37. Prominent plasticity of Mg-based bulk metallic glass composites by ex-situ spherical ti particles10.1016/j.intermet.2012.03.038 ↗
38. Mechanical properties enhanced by the dispersion of porous mo particles in the biodegradable solid and bi-phase core–shell structure of Mg-based bulk metallic glass composites for applications in orthopedic implants10.1016/j.jallcom.2021.160233 ↗
39. Enhanced mechanical performance of mg metallic glass with porous mo particles10.1063/1.2828037 ↗
40. Dispersion toughening of Mg-based bulk metallic glass reinforced with porous mo particles10.1016/j.intermet.2009.09.006 ↗
41. Thermoplastic forming ability of a Mg-base bulk metallic glass composites reinforced with porous mo particles10.1016/j.intermet.2010.01.022 ↗
42. Improvement of mechanical properties in MgCuYNdAg bulk metallic glasses with adding mo particles10.1016/j.jallcom.2010.04.066 ↗
43. High-Strength Mg-Based bulk metallic glass composites with remarkable plasticity10.3139/146.110085 ↗
44. Porous NiTi particle dispersed Mg-Zn-Ca bulk metallic glass matrix composites10.3390/ma11101959 ↗
45. Enhanced plasticity in Mg-based bulk metallic glass composite reinforced with ductile nb particles10.1063/1.2423234 ↗
46. Shear bands in metallic glasses10.1016/j.mser.2013.04.001 ↗
47. Masumoto · Acta Met. · 1971 · 19 · 72510.1016/0001-6160(71)90028-9 ↗
48. Shear-band-to-crack transition in bulk metallic glasses under quasi-static and dynamic shearing10.1016/j.jnoncrysol.2019.119484 ↗
49. A bi-phase core-shell structure of Mg-based bulk metallic glass for application in orthopedic fixation implants10.1016/j.msec.2020.110783 ↗
50. Biodegradable materials for bone defect repair
51. A study on factors affecting the degradation of magnesium and a magnesium-yttrium alloy for biomedical applications
52. Revent progress in corrosion and protection of magnesium alloys10.1002/adem.200500013 ↗
53. M. Degradation of magnesium and its alloys: dependence on the composition of the synthetic biological media10.1002/jbm.a.32106 ↗
54. Corrosion of magnesium in humid air10.1016/j.corsci.2003.09.010 ↗
55. Porous nanohydroxyapatite/collagen scaffolds loading insulin PLGA particles for restoration of critical size bone defect10.1021/acsami.6b13566 ↗
56. Potential bioactive coating system for high-performance absorbable magnesium bone implants
57. MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants10.1038/nmat2542 ↗
58. Materials, A.S. f T. a. (ASTM, Philadelphia, PA, 2004.
59. In vivo and in vitro degradation comparison of pure mg, Mg-10Gd and Mg-2Ag: a short term study10.22203/eCM.v033a07 ↗
60. F. In vitro and in vivo evaluation of biodegradable, open-porous scaffolds made of sintered magnesium W4 short fibres10.1016/j.actbio.2013.03.035 ↗
61. ASTM International, West Conshohocken, PA, 2011.
62. Galster · 1991
63. Song · 2001 · 255
64. Effect of simulated body fluid formulation on orthopedic device apatite-forming ability assessment10.1002/jbm.b.35207 ↗
65. Decoding the "fingerprint" of implant materials: insights into the foreign body reaction
66. Introduction of enzyme-responsivity in biomaterials to achieve dynamic reciprocity in cell-material interactions10.1021/acs.biomac.0c00930 ↗
67. Toward targeted invasive predator control: developing pH-responsive subcutaneous implants for native mammals10.1021/acsapm.2c01041 ↗
68. A novel surgical technique for a rat subcutaneous implantation of a tissue engineered scaffold10.1016/j.acthis.2018.02.010 ↗
69. Orthopedic implants and devices for bone fractures and defects: past, present and perspective
70. Evaluation of biomechanical properties and morphometric structures of the trachea in pigs and rabbits10.21873/invivo.12884 ↗
71. MicroCT and contrast-enhanced microCT to study the in vivo degradation behavior and biocompatibility of candidate metallic intravascular stent materials10.1016/j.actbio.2024.11.017 ↗
72. In vivo micro-computed tomography evaluation of radiopaque, polymeric device degradation in normal and inflammatory environments10.1016/j.actbio.2024.04.031 ↗
73. Method validation of an inductively coupled plasma mass spectrometry (ICP-MS) assay for the analysis of magnesium, copper and zinc in red blood cells10.1016/j.jmsacl.2024.10.003 ↗
74. Metallic glasses for biodegradable implants10.1016/j.actamat.2019.07.008 ↗
75. Corrosion behavior of severely plastically deformed mg and mg alloys10.1016/j.jma.2022.09.007 ↗
76. Recently deepened insights regarding mg corrosion and advanced engineering applications of mg alloys10.1016/j.jma.2023.08.012 ↗
77. Corrosion evaluation of Al-Cu-Mn-Zr cast alloys in 3.5% NaCl solution10.1038/s41529-024-00519-w ↗
78. Mechanical performance and corrosion behaviour of Zr-based bulk metallic glass produced by selective laser melting10.1016/j.matdes.2020.108532 ↗
79. Effects of nanoscale chemical heterogeneity on the wear, corrosion, and tribocorrosion resistance of Zr-based thin film metallic glasses10.1016/j.surfcoat.2020.126324 ↗
80. Corrosion of, and cellular responses to Mg-Zn-Ca bulk metallic glasses10.1016/j.biomaterials.2009.11.015 ↗
81. Chloride-induced alterations of the passive film on 316L stainless steel and blocking effect of pre-passivation10.1016/j.electacta.2019.135159 ↗
82. Surface engineering of pure magnesium in medical implant applications10.1016/j.heliyon.2024.e31703 ↗
83. Mg-Zr-Sr alloys as biodegradable implant materials10.1016/j.actbio.2012.04.028 ↗
84. In vitro evaluation of a novel Mg–Sn–Ge ternary alloy for orthopedic applications10.1016/j.jallcom.2023.169813 ↗
85. Behavior of Al-Zr intermetallic compound particles under high-amplitude ultrasound irradiation into molten aluminum10.1016/j.jallcom.2022.165128 ↗
86. Structural and electrochemical study of resorbable Ca32Mg12Zn38Yb18-xBx (x=1, 2, 3) metallic glasses in ringer's solution10.1016/j.jallcom.2019.152313 ↗
87. Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix10.1016/j.biomaterials.2010.04.013 ↗
88. Osteogenic programming of human mesenchymal stem cells with highly efficient intracellular delivery of RUNX210.1002/sctm.17-0137 ↗
89. The role of Ca(2+) /Calcineurin/NFAT signalling pathway in osteoblastogenesis10.1111/cpr.13122 ↗
90. Low-dose strontium stimulates osteogenesis but high-dose doses cause apoptosis in human adipose-derived stem cells via regulation of the ERK1/2 signaling pathway10.1186/s13287-017-0726-8 ↗