Fabrication of a disposable electrode based on recordable gold compact disc modified with Bi-Bi2O2CO3@ graphitic carbon nitride nanocomposite for the simultaneous detection of mesalazine and uric acid in biological fluids
Source abstract
Abstract
A homemade disposable gold electrode was fabricated from gold compact disc (Au-CDs) and modified with Bi-Bi 2O 2CO 3@g-C 3N 4 nanocomposite for the simultaneous detection of mesalazine (5-amino salicylic acid; 5-ASA) and uric acid (UA) in aqueous solutions. The Bi-Bi 2O 2CO 3@g-C 3N 4 nanocomposite was characterized by Fourier transform infrared spectroscopy, energy-dispersive X-ray spectroscopy, field emission scanning electron microscopy and photoluminescence spectroscopy. The analytical response of the modified g-CDs electrode towards 5-ASA and UA was evaluated by cyclic voltammetry and differential pulse voltammetry. Under optimal conditions, the modified g-CDs electrode was able to detect 5-ASA and UA in the concentration ranges of 1.0–160 µmol L −1 and 10–190 µmol L −1 with detection limits of 0.65 µmol L −1 and 3.07 µmol L −1 for 5-ASA and UA, respectively. The prepared Bi-Bi 2O 2CO 3@g-C 3N 4 nanocomposite exhibited high sensitivity and selectivity towards 5-ASA and UA in urine and plasma samples with recoveries in the range of 91.0 % - 109.3 %.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Electrochemical sensors and biosensors · Advanced biosensing and bioanalysis techniques · Analytical Chemistry and Sensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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