journal article·2015-06

Soft‐lithographically fabricated nanofluidic channels for single‐DNA measurements

Evgeni Sperling, Mandy Hohlfeld, Michael Mertig

physica status solidi (a)· Volume 212· Issue 6
Publisher page

Abstract

We report on the fabrication of submicrometer wide channels by applying advanced soft lithography and focused ion beam patterning. Using so‐called hard PDMS, mechanically stable channels are obtained down to 375 nm width. Channels down to ∼100 nm width are made from Ormostamp. The channels can be filled with DNA solution. Manipulation of the DNA transport through the channels is accomplished by applying electrophoretic forces.
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Research context

OpenAlex topics: Nanofabrication and Lithography Techniques · Microfluidic and Capillary Electrophoresis Applications · Nanopore and Nanochannel Transport Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Professur für Physikalische Chemie, Mess‐ und Sensortechnik Technische Universität Dresden, 01062 Dresden Germany

Kurt‐Schwabe‐Institut für Mess‐ und Sensortechnik e.V. Meinsberg, 04736 Waldheim Germany

References (30)

Show source-provided references
1. 10.1126/science.122581010.1126/science.1225810 ↗
2. 10.1088/0953-8984/23/18/18411910.1088/0953-8984/23/18/184119 ↗
3. 10.1093/nar/gku55610.1093/nar/gku556 ↗
4. 10.1021/nl203503s10.1021/nl203503s ↗
5. 10.1093/nar/gkq43410.1093/nar/gkq434 ↗
6. 10.1073/pnas.040384910110.1073/pnas.0403849101 ↗
7. 10.1103/PhysRevLett.94.19610110.1103/PhysRevLett.94.196101 ↗
8. 10.1529/biophysj.105.07473210.1529/biophysj.105.074732 ↗
9. 10.1103/PhysRevLett.99.05830210.1103/PhysRevLett.99.058302 ↗
10. 10.1016/S0301-4622(02)00166-710.1016/S0301-4622(02)00166-7 ↗
11. 10.1103/PhysRevLett.88.12810310.1103/PhysRevLett.88.128103 ↗
12. 10.1039/b912918a10.1039/b912918a ↗
13. 10.1093/nar/gkl104410.1093/nar/gkl1044 ↗
14. 10.1039/b312592k10.1039/b312592k ↗
15. 10.1021/nl070186110.1021/nl0701861 ↗
16. 10.1103/PhysRevLett.99.23810210.1103/PhysRevLett.99.238102 ↗
17. Persson F. · Nano Lett. · 2009 · 9 · 1383
18. 10.1021/ma101157x10.1021/ma101157x ↗
19. 10.1073/pnas.090400410610.1073/pnas.0904004106 ↗
20. 10.4028/www.scientific.net/DDF.312-315.109110.4028/www.scientific.net/DDF.312-315.1091 ↗
21. 10.1116/1.366288610.1116/1.3662886 ↗
22. 10.1016/j.compscitech.2012.04.01210.1016/j.compscitech.2012.04.012 ↗
23. 10.1021/ma982034l10.1021/ma982034l ↗
24. Micro resist technology Ormostamp – product information.
25. Schott AG D 263 M cover glass – physical and chemical properties.
26. 10.1021/la020169l10.1021/la020169l ↗
27. 10.1016/j.bpj.2009.07.04810.1016/j.bpj.2009.07.048 ↗
28. 10.1021/la034138h10.1021/la034138h ↗
29. 10.1021/nl080300v10.1021/nl080300v ↗
30. 10.1063/1.275720210.1063/1.2757202 ↗