Modelling Deep Tonometry of Lymphedematous Tissue
Source abstract
Abstract
Indentation testing, also refereed to as tonometry in medical diagnostics, is one of the most frequently used methods for studying the properties of soft biological tissues. In the case of lymphedematous tissues, characterized by abnormal accumulation of excess interstitial fluid, the indentation method constitutes an objective alternative for the standard manual palpation test, that is used for evaluation of elastic modulus and time dependent tissue response related to finding parameters of effective compression therapy. This paper focuses on the numerical modelling of a deep indentation test for which the flat cylindrical tip with a surface area of 1 cm2 penetrates the tissue at a constant rate until 1 cm depth is reached. The indentation generates large deformations of skin and subcutaneous tissue and squeezing of part of the interstitial fluid from the compressed region. The skin is modelled as an isotropic neo-Hookean solid and subcutaneous tissue is modelled as a fluid saturated porous matrix. The effective stress law, isotropic neo-Hookean elastic matrix and the Darcy's type of interaction force between phases are adopted for the subcutaneous tissue. The finite element simulations deliver results for time dependent indentation force and pore pressure under the indenter for different and relevant to real tissues properties. The role of the properties and the presence of skin are analysed. The values of maximum reaction force and relaxation time are compared and evaluated as descriptors of mechanical properties of tissues.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Tribology and Lubrication Engineering · Textile materials and evaluations · Tendon Structure and Treatment
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (20)
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