Novel Ti-Zr-Hf-Nb-Fe refractory high-entropy alloys for potential biomedical applications
Source abstract
Abstract
In the present work, the TiZrHfNbFe x (x = 0, 0.25, 0.5, 0.75, 1, 1.5, and 2, molar ratio) refractory high-entropy alloys (HEAs) were developed. The microstructure, mechanical properties, corrosion and wear resistance of the Ti-Zr-Hf-Nb-Fe HEAs were investigated. The Ti-Zr-Hf-Nb-Fe HEAs exhibited a dendrite structure with body-centered-cubic (BCC) + Laves phases. Among them, the TiZrHfNbFe 0.5 HEA displayed good comprehensive mechanical properties with the hardness of 420 HV, compressive strength of 1450 MPa, and plastic strain of about 8%. In addition, the TiZrHfNbFe 0.5 HEA possessed better corrosion resistance than that of the Ti6Al4V and the other Ti-Zr-Hf-Nb-Fe HEAs in phosphate buffer saline (PBS) solution, which might be related to the generation of more protective oxide films on its surface. Furthermore, the wear resistance of the Ti-Zr-Hf-Nb-Fe HEAs increased with the raise of the Fe content. The TiZrHfNbFe 0.5 HEA demonstrated superior dry and wet wear resistance in comparison with the Ti6Al4V alloy. Therefore, the good mechanical properties, high corrosion, and wear resistance, the biocompatible constituent elements, as well as the low cost of the Fe addition render the Ti-Zr-Hf-Nb-Fe HEAs as promising candidates as biomedical-implantation materials.
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Research context
OpenAlex topics: High Entropy Alloys Studies · Advanced materials and composites · High-Temperature Coating Behaviors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (86)
Show source-provided references
1. Sustainable biomaterials and their applications: a short review
2. High-entropy ceramics10.1038/s41578-019-0170-8 ↗
3. Bulk metallic glasses for biomedical applications10.1007/s11837-009-0128-1 ↗
4. Biomedical materials and techniques to improve the tribological, mechanical and biomedical properties of orthopedic implants – a review article10.1016/j.jallcom.2017.04.231 ↗
5. Ti based biomaterials, the ultimate choice for orthopaedic implants – a review10.1016/j.pmatsci.2008.06.004 ↗
6. Titanium alloys in total joint replacement—a materials science perspective10.1016/S0142-9612(97)00146-4 ↗
7. Effect of the environment on wear ranking and corrosion of biomedical CoCrMo alloys
8. Wear characteristics of metallic biomaterials: a review10.3390/ma8052749 ↗
9. Pin-on-disk wear behavior in a like-on-like configuration in a biological environment of high carbon cast and low carbon forged Co–29Cr–6Mo alloys10.1016/j.actamat.2006.10.005 ↗
10. Microstructural development in equiatomic multicomponent alloys10.1016/j.msea.2003.10.257 ↗
11. Nanostructured high‐entropy alloys with multiple principal elements: novel alloy design concepts and outcomes10.1002/adem.200300567 ↗
12. Sluggish diffusion in Co–Cr–Fe–Mn–Ni high-entropy alloys10.1016/j.actamat.2013.04.058 ↗
13. Physical metallurgy of high-entropy alloys10.1007/s11837-015-1583-5 ↗
14. Corrosion-resistant high-entropy alloys: a review10.3390/met7020043 ↗
15. Mechanical properties of high-entropy alloys
16. Fatigue behavior of Al0.5CoCrCuFeNi high entropy alloys10.1016/j.actamat.2012.06.046 ↗
17. Phases, microstructure and mechanical properties of AlxCoCrFeNi high-entropy alloys at elevated temperatures10.1016/j.jallcom.2013.11.084 ↗
18. Refractory high-entropy alloys10.1016/j.intermet.2010.05.014 ↗
19. NbMoTaW refractory high entropy alloy composites strengthened by in-situ metal-non-metal compounds10.1016/j.jallcom.2019.153423 ↗
20. Effects of annealing on the microstructure and magnetic property of the mechanically alloyed FeSiBAlNiM (M=Co, Cu, Ag) amorphous high entropy alloys10.1016/j.jmmm.2017.01.028 ↗
21. A new strategy to design eutectic high-entropy alloys using mixing enthalpy10.1016/j.intermet.2017.09.001 ↗
22. Promising properties and future trend of eutectic high entropy alloys10.1016/j.scriptamat.2020.06.022 ↗
23. Hierarchical crack buffering triples ductility in eutectic herringbone high-entropy alloys10.1126/science.abf6986 ↗
24. Corrosion and tribocorrosion behavior of equiatomic refractory medium entropy TiZr(Hf, Ta, Nb) alloys in chloride solutions10.1016/j.corsci.2022.110166 ↗
25. A refractory Hf25Nb25Ti25Zr25 high-entropy alloy with excellent structural stability and tensile properties10.1016/j.matlet.2014.05.134 ↗
26. A novel quaternary equiatomic Ti-Zr-Nb-Ta medium entropy alloy (MEA)10.1016/j.intermet.2018.07.008 ↗
27. Novel TiNbTaZrMo high-entropy alloys for metallic biomaterials10.1016/j.scriptamat.2016.10.028 ↗
28. TiZrNbTaMo high-entropy alloy designed for orthopedic implants: As-cast microstructure and mechanical properties10.1016/j.msec.2016.12.057 ↗
29. Mechanical properties of Nb25Mo25Ta25W25 and V20Nb20Mo20Ta20W20 refractory high entropy alloys10.1016/j.intermet.2011.01.004 ↗
30. Formation, structure and properties of biocompatible TiZrHfNbTa high-entropy alloys10.1080/21663831.2019.1584592 ↗
31. Microstructure and mechanical properties of refractory MoNbHfZrTi high-entropy alloy10.1016/j.matdes.2015.05.019 ↗
32. Ti-Zr-Nb based BCC solid solution alloy containing trace Cu and Ag with low modulus and excellent antibacterial properties
33. Corrosion behavior of a non-equiatomic CoCrFeNiTi high-entropy alloy: a comparison with 304 stainless steel in simulated body fluids10.1016/j.jallcom.2021.163036 ↗
34. Design and development of Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys for metallic biomaterials10.1016/j.matdes.2021.109548 ↗
35. Influence of molybdenum on the microstructure, mechanical properties and corrosion resistance of Ti20Ta20Nb20(ZrHf)20-xMox (Where: x = 0, 5, 10, 15, 20) high entropy alloys10.3390/ma15010393 ↗
36. Microstructural, mechanical and electrochemical characterization of TiZrTaHfNb and Ti1.5ZrTa0.5Hf0.5Nb0.5 refractory high-entropy alloys for biomedical applications10.1016/j.intermet.2019.106572 ↗
37. Bio-corrosion behavior and in vitro biocompatibility of equimolar TiZrHfNbTa high-entropy alloy10.1016/j.intermet.2020.106845 ↗
38. Corrosion behavior of Hf0.5Nb0.5Ta0.5Ti1.5Zr refractory high-entropy in aqueous chloride solutions10.1016/j.elecom.2018.11.009 ↗
39. Design and properties of novel Ti–Zr–Hf–Nb–Ta high-entropy alloys for biomedical applications10.1016/j.intermet.2021.107421 ↗
40. Assessment of biocompatibility of novel TiTaHf-based high entropy alloys for utility in orthopedic implants10.1016/j.matchemphys.2021.124573 ↗
41. Mechanical, corrosion, and wear properties of biomedical Ti–Zr–Nb–Ta–Mo high entropy alloys10.1016/j.jallcom.2020.157997 ↗
42. Solid-solution phase formation rules for multi-component alloys10.1002/adem.200700240 ↗
43. Prediction of high-entropy stabilized solid-solution in multi-component alloys10.1016/j.matchemphys.2011.11.021 ↗
44. Effect of Al addition on the microstructure, mechanical and wear properties of TiZrNbHf refractory high entropy alloys10.1016/j.triboint.2021.107031 ↗
45. Microstructural features and dry - sliding wear response of MoTaNbZrTi high entropy alloy10.1016/j.matchemphys.2017.08.036 ↗
46. Composition dependence of the microstructure and the mechanical properties of nano/ultrafine-structured Ti–Cu–Ni–Sn–Nb alloys10.1016/j.actamat.2004.03.006 ↗
47. Corrosion behavior of CuCrFeNiMn high entropy alloy system in 1 M sulfuric acid solution10.1002/maco.201106072 ↗
48. Understanding effect of 3.5 wt% NaCl on the corrosion of Al0. 1CoCrFeNi high-entropy alloy10.1016/j.jnucmat.2017.08.015 ↗
49. Passive film of 18-8 stainless steel structure and its function10.1016/0010-938X(73)90031-0 ↗
50. Contact and rubbing of flat surfaces10.1063/1.1721448 ↗
51. Microstructure and wear behavior of a refractory high entropy alloy10.1016/j.ijrmhm.2016.02.006 ↗
52. Effect of Nb content on thermal stability, mechanical and corrosion behaviors of hypoeutectic CoCrFeNiNbχ high-entropy alloys10.1557/jmr.2018.103 ↗
53. The intrinsic mechanism of corrosion resistance for FCC high entropy alloys10.1007/s11431-017-9114-1 ↗
54. Nanocrystalline materials and coatings10.1016/j.mser.2004.07.001 ↗
55. Effect of grain size on corrosion: a review10.5006/1.3462912 ↗
56. The effect of Nb-content on the microstructures and corrosion properties of CrFeCoNiNbx high-entropy alloys10.3390/ma12223716 ↗
57. Influence of niobium and zirconium alloying additions on the anodic dissolution behavior of activated titanium in HCl solutions10.1149/1.1337605 ↗
58. The influence of niobium and vanadium on passivity of titanium-based implants in physiological solution10.1016/S0142-9612(03)00252-7 ↗
59. Microstructure and electrochemical behaviors of equiatomic TiMoVCrZr and Ti-rich TiMoVCrZr high-entropy alloys for metallic biomaterials10.24425/amm.2020.133692 ↗
60. Systematic study of (MoTa) NbTiZr medium- and high-entropy alloys for biomedical implants- In vivo biocompatibility examination10.1016/j.jmst.2020.10.049 ↗
61. Research on suitable strength, elastic modulus and abrasion resistance of Ti–Zr–Nb medium entropy alloys (MEAs) for implant adaptation10.1016/j.intermet.2021.107401 ↗
62. Wear resistance of Cu/Ag multilayers: a microscopic study10.1021/acsami.8b03015 ↗
63. Tribological behaviour of biomedical Ti–Zr-based shape memory alloys10.1007/s12598-017-0882-0 ↗
64. Reciprocating sliding wear behavior of high entropy alloys in dry and marine environments10.1016/j.matchemphys.2017.07.031 ↗
65. Microstructure and wear properties of nitrided AlCoCrFeNi high-entropy alloy10.1016/j.matchemphys.2017.05.029 ↗
66. Influence of titanium on microstructure, phase formation and wear behaviour of AlCoCrFeNiTix high-entropy alloy10.3390/e20070505 ↗
67. Dry wear behavior and mechanism of a Fe-based bulk metallic glass: description by Hertzian contact calculation and finite-element method simulation10.1016/j.jnoncrysol.2020.120065 ↗
68. Tuning element distribution, structure and properties by composition in high-entropy alloys10.1038/s41586-019-1617-1 ↗
69. Microstructures and properties of high-entropy alloys10.1016/j.pmatsci.2013.10.001 ↗
70. Third-generation biomedical materials10.1126/science.1067404 ↗
71. Enhanced wear, corrosion, and corrosive-wear resistance of the biocompatible Ti-based bulk metallic glass by oxidation treatment10.1016/j.jnoncrysol.2021.121231 ↗
72. A novel TiZrNb medium entropy alloy (MEA) with appropriate elastic modulus for biocompatible materials10.1016/j.mseb.2021.115226 ↗
73. Solidification microstructures of the ingots obtained by arc melting and cold crucible levitation melting in TiNbTaZr MEdium-entropy Alloy and TiNbTaZrX (X = V, Mo, W) high-entropy alloys10.3390/e21050483 ↗
74. New TiTaNbZrMo high-entropy alloys for metallic biomaterials10.1088/2053-1591/ac2f0b ↗
75. Design and fabrication of Ti-Zr-Hf-Cr-Mo and Ti-Zr-Hf-Co-Cr-Mo high-entropy alloys as metallic biomaterials
76. Designing biocompatible Ti-based metallic glasses for implant applications10.1016/j.msec.2012.11.015 ↗
77. Biocompatibility and osteogenesis of refractory metal implants, titanium, hafnium, niobium, tantalum and rhenium10.1016/S0142-9612(00)00275-1 ↗
78. Design of high-ductile medium entropy alloys for dental implants10.1016/j.msec.2020.110959 ↗
79. Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials10.1016/j.scriptamat.2019.07.011 ↗
80. A single-phase bcc high-entropy alloy in the refractory Zr-Nb-Ti-V-Hf system10.1016/j.scriptamat.2018.04.009 ↗
81. Design and development of (Ti, Zr, Hf)-Al based medium entropy alloys and high entropy alloys10.1016/j.matchemphys.2021.125409 ↗
82. Effects of V content on the microstructure and mechanical properties of Nb31Ti37-Zr26Al6V refractory medium-entropy alloys10.1016/j.intermet.2022.107472 ↗
83. Recent metallic materials for biomedical applications10.1007/s11661-002-0109-2 ↗
84. Cytotoxicity evaluation of 43 metal salts using murine fibroblasts and osteoblastic cells10.1002/(SICI)1097-4636(199802)39:2<331::AID-JBM22>3.0.CO;2-E ↗
85. New TiZrNbTaFe high entropy alloy used for medical applications10.1088/1757-899X/400/2/022049 ↗
86. Bio-functionalization of a novel biocompatible high entropy alloy used for bone implants