Green synthesis and eco-biological evaluation of Ag/Fe bimetallic nanoparticles using Vallaris solanacea leaf extract targeting insecticide resistance
Source abstract
Abstract
The emergence of insecticide resistance presents a major challenge in pest control and agriculture, while the use of conventional pesticides raises environmental and health concerns. This study addresses these issues through the green synthesis of Ag/Fe bimetallic nanoparticles (BMNPs) using Vallaris solanacea plant extract and evaluates their eco-biological activities. The synthesized Ag/Fe BMNPs, with an average size of 30 nm as determined by SEM, were characterized by UV–Vis spectroscopy, FTIR, EDX, and SEM. In vitro assays revealed significant anti-inflammatory (91%), antioxidant (95%), anti-diabetic, anti-hemolytic, and antimicrobial activities. Additionally, the nanoparticles demonstrated 100% mortality against Sitophilus oryzae (rice weevil) and exhibited 97% degradation of the pesticide Novacide, indicating potent pesticidal and environmental remediation capabilities. Computational analysis, including molecular docking and molecular dynamics simulations, revealed strong interactions between Ag/Fe BMNPs and insecticide resistance (IR) proteins, with binding energies surpassing those of traditional pesticides, suggesting an ability to circumvent resistance mechanisms. These findings highlight the potential of Ag/Fe BMNPs as a sustainable, eco-friendly alternative for pest management and environmental applications in agriculture and beyond.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Moringa oleifera research and applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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