journal article·2017-11

Multifunctional Hybrids Based on 2D Fluorinated Graphene Oxide and Superparamagnetic Iron Oxide Nanoparticles

Sruthi Radhakrishnan, Parambath M. Sudeep, Jun Hyoung Park, Cristiano F. Woellner, Kierstein Maladonado, Douglas S. Galvao, Benny Abraham Kaipparettu, Chandra Sekhar Tiwary, Pulickel M. Ajayan

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Abstract

Carbon-based nanomaterials have garnered a lot of attention in the research of yesteryear. Here this study reports a composite based on fluorinated graphene oxide—a multifunctional subsidiary of graphene; and iron oxide nanoparticles as a contrast agent for magnetic resonance imaging (MRI). Extensive structural and functional characterization is carried out to understand composite behavior toward biotoxicity and its performance as a contrast agent. The electron withdrawing fluorine group decreases the charge transfer to iron oxide increasing the magnetic saturation of the composite thus enhancing the contrast. The interaction of paramagnetic and superparamagnetic systems yields a superior contrast agent for MRI and fluorescent imaging.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Nanoparticle-Based Drug Delivery · Graphene research and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Materials Science and Nano Engineering Rice University Houston TX 77005 USA

Department of Mechanical and Industrial Engineering University of Toronto Toronto M5S3E3 Canada

Department of Molecular and Human Genetics Baylor College of Medicine Houston TX 77030 USA

Applied Physics Department State University of Campinas – UNICAMP 13083‐859 Campinas Sao Paulo Brazil

Small Animal Imaging Facility The University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Dan L. Duncan Comprehensive Cancer Center Baylor College of Medicine Houston TX 77030 USA

Funding

Air Force Office of Scientific Research · Fundação de Amparo à Pesquisa do Estado de São Paulo

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