journal article·2019-08Open access

Cell Uptake of Lipid‐Coated Diamond

Aryan Morita, Felipe P. Perona Martinez, Mayeul Chipaux, Nicolas Jamot, Simon R. Hemelaar, Kiran J. van der Laan, Romana Schirhagl

Abstract

Abstract Fluorescent nanodiamonds (FNDs) can be used as nanoscale magnetic resonance sensors and stable optical labels. As a first step for using FNDs as nanosensors inside cells, they have to be ingested. Several techniques that improve particle uptake have been used. A simple approach based on commercially available liposomes is used to improve uptake. Uptake into colon cancer cells (HT‐29 cells) is demonstrated. Additionally, it is shown for the first time that one can facilitate diamond uptake into yeast cells by removing the cell wall and creating a so‐called spheroplast. Finally, the characteristics of FNDs coated with lipids and their behavior inside the cells are evaluated.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Diamond and Carbon-based Materials Research · Carbon Nanotubes in Composites · Ion-surface interactions and analysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomedical Engineering University Medical Center Groningen Antonius Deusinglaan 1 9713 AV Groningen The Netherlands

Department of Dental Biomedical Sciences Faculty of Dentistry Universitas Gadjah Mada Jl Denta 1 55281 Yogyakarta Indonesia

Funding

Foundation for Fundamental Research on Matter · Nederlandse Organisatie voor Wetenschappelijk Onderzoek

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