A review of polycyclic aromatic hydrocarbon-induced microbial deterioration of mediterranean heritage and conservation strategies
Source abstract
Abstract
The Mediterranean region, distinguished by its cultural heritage and industrialization, suffers from significant pollution levels of polycyclic aromatic hydrocarbons (PAHs) due to frequent petroleum-related activities such as petroleum extraction and consumption. Being dominant pollutants, PAHs cause significant deterioration of historic buildings and materials. This review comprehensively explores PAH-induced heritage deterioration, especially PAH-induced microbial deterioration, and explores current solutions and future perspectives for cultural heritage preservation.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Building materials and conservation · Conservation Techniques and Studies · Cultural Heritage Materials Analysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
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1. Gupte, A., Tripathi, A., Patel, H., Rudakiya, D. & Gupte, S. Bioremediation of polycyclic aromatic hydrocarbon (PAHs): a perspective. Open Biotechnol. J. 10, 363–378 (2016).10.2174/1874070701610010363 ↗
2. Jesus, F. et al. A review on polycyclic aromatic hydrocarbons distribution in freshwater ecosystems and their toxicity to benthic fauna. Sci. Total Environ. 820, 153282 (2022).10.1016/j.scitotenv.2022.153282 ↗
3. Liu, C. et al. The sediment-water diffusion and risk assessment of PAHs in different types of drinking water sources in the Yangtze River Delta, China. J. Clean. Prod. 309, 127456 (2021).10.1016/j.jclepro.2021.127456 ↗
4. Dat, N.-D. & Chang, M. B. Review on characteristics of PAHs in atmosphere, anthropogenic sources and control technologies. Sci. Total Environ. 609, 682–693 (2017).10.1016/j.scitotenv.2017.07.204 ↗
5. Alegbeleye, O. O., Opeolu, B. O. & Jackson, V. A. Polycyclic aromatic hydrocarbons: a critical review of environmental occurrence and bioremediation. Environ. Manag. 60, 758–783 (2017).10.1007/s00267-017-0896-2 ↗
6. Yang, W., Lang, Y. & Li, G. Cancer risk of polycyclic aromatic hydrocarbons (PAHs) in the soils from Jiaozhou Bay wetland. Chemosphere 112, 289–295 (2014).10.1016/j.chemosphere.2014.04.074 ↗
7. Wild, S. R. & Jones, K. C. Polynuclear aromatic hydrocarbons in the United Kingdom environment: a preliminary source inventory and budget. Environ. Pollut. 88, 91–108 (1995).10.1016/0269-7491(95)91052-M ↗
8. Sims, R. C. & Overcash, M. R. Fate of polynuclear aromatic compounds (PNAs) in soil-plant systems. In Residue Reviews: Residues of Pesticides and Other Contaminants in the Total Environment 88, 1–68 (Springer, 1983).10.1007/978-1-4612-5569-7_1 ↗
9. Liu, T. et al. Emissions of BTEXs, NMHC, PAHs, and PCDD/Fs from co-processing of oil-based drilling cuttings in brick kilns. J. Environ. Manag. 304, 114170 (2022).10.1016/j.jenvman.2021.114170 ↗
10. Margesin, R., Walder, G. & Schinner, F. Bioremediation assessment of a BTEX-contaminated soil. Acta Biotechnol. 23, 29–36 (2003).10.1002/abio.200390004 ↗
11. Bashan, N. F., Li, W. & Wang, Q. R. Dynamics of PM2. 5 and network activity during extreme pollution events. NPJ Clim. Atmos. Sci. 7, 171 (2024).10.1038/s41612-024-00716-z ↗
12. Zhang, B. et al. Marine oil spills—oil pollution, sources and effects. In World Seas: an Environmental Evaluation 2nd edn (eds Sheppard, C. B. T., W. S. and E. E.) 391–406 https://doi.org/10.1016/B978-0-12-805052-1.00024-3 (Academic Press, 2019).10.1016/B978-0-12-805052-1.00024-3 ↗
13. U.S. Environmental Protection Agency|US EPA. https://www.epa.gov/.
14. PubChem. https://pubchem.ncbi.nlm.nih.gov/.
15. PyMOL|pymol.org. https://www.pymol.org/.
16. Ferrante, M. et al. PAHs in seafood from the Mediterranean Sea: an exposure risk assessment. Food Chem. Toxicol. 115, 385–390 (2018).10.1016/j.fct.2018.03.024 ↗
17. Desalme, D., Binet, P. & Chiapusio, G. Challenges in tracing the fate and effects of atmospheric polycyclic aromatic hydrocarbon deposition in vascular plants. Environ. Sci. Technol. 47, 3967–3981 (2013).10.1021/es304964b ↗
18. John, K. et al. Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon–DNA adduct levels in human prostate. Prostate 69, 505–519 (2009).10.1002/pros.20898 ↗
19. Diggs, D. L. et al. Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective. J. Environ. Sci. Heal. part c. 29, 324–357 (2011).10.1080/10590501.2011.629974 ↗
20. Adeleye, A. O. et al. Distribution and ecological risk of organic pollutants in the sediments and seafood of Yangtze Estuary and Hangzhou Bay, East China Sea. Sci. Total Environ. 541, 1540–1548 (2016).10.1016/j.scitotenv.2015.09.124 ↗
21. Lee, B.-J., Kim, B. & Lee, K. Air pollution exposure and cardiovascular disease. Toxicol. Res. 30, 71–75 (2014).10.5487/TR.2014.30.2.071 ↗
22. Abdel-Shafy, H. I. & Mansour, M. S. M. A review on polycyclic aromatic hydrocarbons: source, environmental impact, effect on human health and remediation. Egypt. J. Pet. 25, 107–123 (2016).10.1016/j.ejpe.2015.03.011 ↗
23. Haynes, B. S. & Wagner, H. G. Soot formation. Prog. energy Combust. Sci. 7, 229–273 (1981).10.1016/0360-1285(81)90001-0 ↗
24. Ricciardi, M. et al. Analysis of PAHs (polycyclic aromatic hydrocarbons) and other main components in black crusts collected from the Monumental Cemetery of Milan (Italy). In Proc. J. Phys. Conf. Ser. 2204 12027 (IOP Publishing, 2022).10.1088/1742-6596/2204/1/012027 ↗
25. Ozga, I. et al. Pollution impact on the ancient ramparts of the Moroccan city Salé. J. Cult. Herit. 14, S25–S33 (2013).10.1016/j.culher.2012.10.018 ↗
26. Gianguzza, A., Governanti, M., Orecchio, S. & Piazzese, D. Identification of polycyclic aromatic hydrocarbons (PAHS) in the black crusts of Sicilian stone monuments: distribution and sources. Sci. Technol. Cult. Herit. 13, 53–61 (2004).
27. Orecchio, S. Analytical method, pattern and sources of polycyclic aromatic hydrocarbons (PAHs) in the stone of the Temples of Agrigento (Italy). J. Hazard. Mater. 176, 339–347 (2010).10.1016/j.jhazmat.2009.11.033 ↗
28. Slezakova, K. et al. Evaluation of atmospheric deposition and patterns of polycyclic aromatic hydrocarbons in façades of historic monuments of Oporto (Portugal). Int. J. Environ. Anal. Chem. 93, 1052–1064 (2013).10.1080/03067319.2013.775279 ↗
29. Ilieș, D. C. et al. Investigations of museum indoor microclimate and air quality. Case study from Romania. Atmosphere12, 286 (2021).10.3390/atmos12020286 ↗
30. Zain ul Arifeen, M. et al. Anaerobic biodegradation of polycyclic aromatic hydrocarbons (PAHs) by fungi isolated from anaerobic coal-associated sediments at 2.5 km below the seafloor. Chemosphere 303, 135062 (2022).10.1016/j.chemosphere.2022.135062 ↗
31. Lundstedt, S., Haglund, P. & Öberg, L. Degradation and formation of polycyclic aromatic compounds during bioslurry treatment of an aged gasworks soil. Environ. Toxicol. Chem. Int. J. 22, 1413–1420 (2003).10.1002/etc.5620220701 ↗
32. Nzila, A. Biodegradation of high-molecular-weight polycyclic aromatic hydrocarbons under anaerobic conditions: overview of studies, proposed pathways and future perspectives. Environ. Pollut. 239, 788–802 (2018).10.1016/j.envpol.2018.04.074 ↗
33. Ahmad, I. Microalgae–bacteria consortia: a review on the degradation of polycyclic aromatic hydrocarbons (PAHs). Arab. J. Sci. Eng. 47, 19–43 (2022).10.1007/s13369-021-06236-9 ↗
34. López Garrido, P. H., González-Sánchez, J. & Escobar Briones, E. Fouling communities and degradation of archeological metals in the coastal sea of the Southwestern Gulf of Mexico. Biofouling 31, 405–416 (2015).10.1080/08927014.2015.1048433 ↗
35. Suphaphimol, N. et al. Identification of microorganisms dwelling on the 19th century lanna mural paintings from Northern Thailand using culture-dependent and-independent approaches. Biology 11, 228 (2022).10.3390/biology11020228 ↗
36. Warscheid, T. Impacts of microbial biofilms in the deterioration of inorganic building materials and their relevence for the conservation practice. Int. J. Restor. Build. Monum. 2, 493–503 (1996).
37. Dornieden, T., Gorbushina, A. A. & Krumbein, W. E. Biodecay of cultural heritage as a space/time-related ecological situation—an evaluation of a series of studies. Int. Biodeterior. Biodegrad. 46, 261–270 (2000).10.1016/S0964-8305(00)00107-4 ↗
38. Martino, P. D. What about biofilms on the surface of stone monuments? Open Conf. Proc. J. 6, 14–28 (2016).10.2174/2210289201607020014 ↗
39. Villa, F., Stewart, P. S., Klapper, I., Jacob, J. M. & Cappitelli, F. Subaerial biofilms on outdoor stone monuments: changing the perspective toward an ecological framework. Bioscience 66, 285–294 (2016).10.1093/biosci/biw006 ↗
40. Albertano, P. Cyanobacterial biofilms in monuments and caves. In: Ecology of Cyanobacteria II: Their Diversity in Space and Time 317–343 (Springer, 2012).10.1007/978-94-007-3855-3_11 ↗
41. Tonon, C. et al. Microenvironmental features drive the distribution of lichens in the House of the Ancient Hunt, Pompeii, Italy. Int. Biodeterior. Biodegrad. 136, 71–81 (2019).10.1016/j.ibiod.2018.10.012 ↗
42. Ahmed, E. & Holmström, S. J. M. Siderophores in environmental research: roles and applications. Microb. Biotechnol. 7, 196–208 (2014).10.1111/1751-7915.12117 ↗
43. Wright, J. S. Geomorphology and stone conservation: sandstone decay in stoke-on-trent. Struct. Surv. 20, 50–61 (2002).10.1108/02630800210433828 ↗
44. Gadd, G. M. Geomycology: biogeochemical transformations of rocks, minerals, metals and radionuclides by fungi, bioweathering and bioremediation. Mycol. Res. 111, 3–49 (2007).10.1016/j.mycres.2006.12.001 ↗
45. De Rosa, A. et al. The effects of urban pollution on the “Gesù Nuovo” Façade (Naples, Italy): a diagnostic overview. Atmosphere16, 68 (2025).10.3390/atmos16010068 ↗
46. Leon Campbell, L. & Postgate, J. R. Classification of the spore-forming sulfate-reducing bacteria. Bacteriol. Rev. 29, 359–363 (1965).10.1128/br.29.3.359-363.1965 ↗
47. Urzì, C. & Krumbein, W. E. Microbiological impacts on the cultural heritage. In: Krumbein, W. E (ed). Durability and Change: The Science, Krumbein Heritage. 107–135 (Wiley, 1994).
48. Wang, Y. & Liu, X. Sulfur-oxidizing bacteria involved in the blackening of basalt sculptures of the Leizhou Stone Dog. Int. Biodeterior. Biodegrad. 159, 105207 (2021).10.1016/j.ibiod.2021.105207 ↗
49. Nugari, M. P., Pietrini, A. M., Caneva, G., Imperi, F. & Visca, P. Biodeterioration of mural paintings in a rocky habitat: the Crypt of the Original Sin (Matera, Italy). Int. Biodeterior. Biodegrad. 63, 705–711 (2009).10.1016/j.ibiod.2009.03.013 ↗
50. Oetari, A. et al. Occurrence of fungi on deteriorated old dluwang manuscripts from Indonesia. Int. Biodeterior. Biodegrad. 114, 94–103 (2016).10.1016/j.ibiod.2016.05.025 ↗
51. Warscheid, T., Oelting, M. & Krumbein, W. E. Physico-chemical aspects of biodeterioration processes on rocks with special regard to organic pollutants. Int. Biodeterior. 28, 37–48 (1991).10.1016/0265-3036(91)90032-M ↗
52. Moroni, B. & Pitzurra, L. Biodegradation of atmospheric pollutants by fungi: a crucial point in the corrosion of carbonate building stone. Int. Biodeterior. Biodegrad. 62, 391–396 (2008).10.1016/j.ibiod.2008.03.011 ↗
53. Ortega-Morales, B. O., Gaylarde, C. C., Englert, G. E. & Gaylarde, P. M. Analysis of salt-containing biofilms on limestone buildings of the Mayan culture at Edzna, Mexico. Geomicrobiol. J. 22, 261–268 (2006).10.1080/01490450500182524 ↗
54. Sand, W. & Bock, E. Biodeterioration of mineral materials by microorganisms—biogenic sulfuric and nitric acid corrosion of concrete and natural stone. Geomicrobiol. J. 9, 129–138 (1991).10.1080/01490459109385994 ↗
55. Meng, H., Luo, L., Chan, H. W., Katayama, Y. & Gu, J. D. Higher diversity and abundance of ammonia-oxidizing archaea than bacteria detected at the Bayon Temple of Angkor Thom in Cambodia. Int. Biodeterior. Biodegrad. 115, 234–243 (2016).10.1016/j.ibiod.2016.08.021 ↗
56. Meng, H., Katayama, Y. & Gu, J. D. More wide occurrence and dominance of ammonia-oxidizing archaea than bacteria at three Angkor sandstone temples of Bayon, Phnom Krom and Wat Athvea in Cambodia. Int. Biodeterior. Biodegrad. 117, 78–88 (2017).10.1016/j.ibiod.2016.11.012 ↗
57. Siegesmund, S., Sousa, L. & López-Doncel, R. A. Editorial to the topical collection in Environmental Earth Sciences “Stone in the architectural heritage: from quarry to monuments—environment, exploitation, properties and durability”. Environ. Earth Sci. 77, 1–4 (2018).10.1007/s12665-018-7755-1 ↗
58. Vupputuri, S. et al. Isolation of a sulfur-oxidizing Streptomyces sp. from deteriorating bridge structures and its role in concrete deterioration. Int. Biodeterior. Biodegrad. 97, 128–134 (2015).10.1016/j.ibiod.2014.11.002 ↗
59. Xu, H. B. et al. Lithoautotrophical oxidation of elemental sulfur by fungi including Fusarium solani isolated from sandstone Angkor temples. Int. Biodeterior. Biodegrad. 126, 95–102 (2018).10.1016/j.ibiod.2017.10.005 ↗
60. Heilmann, S., Krishna, S. & Kerr, B. Why do bacteria regulate public goods by quorum sensing? How the shapes of cost and benefit functions determine the form of optimal regulation. Front. Microbiol. 6, 149137 (2015).10.3389/fmicb.2015.00767 ↗
61. Decho, A. W. & Gutierrez, T. Microbial extracellular polymeric substances (EPSs) in ocean systems. Front. Microbiol. 8, 265214 (2017).10.3389/fmicb.2017.00922 ↗
62. Omar, A., Taha, A. & El-Wekeel, F. Microbial degradation of ancient textiles housed in the Egyptian Textile Museum and methods of its control. Egypt. J. Archaeol. Restor. Stud. 9, 27–37 (2019).
63. Karakasidou, K. et al. Microbial diversity in biodeteriorated Greek historical documents dating back to the 19th and 20th century: a case study. Microbiologyopen 7, e00596 (2018).10.1002/mbo3.596 ↗
64. Branysova, T., Demnerova, K., Durovic, M. & Stiborova, H. Microbial biodeterioration of cultural heritage and identification of the active agents over the last two decades. J. Cult. Herit. 55, 245–260 (2022).10.1016/j.culher.2022.03.013 ↗
65. Vasconcellos, V. A., Lins, V. F. C. & Faria, R. A. D. Application of biosensors in the petrochemical industry: a mini review on the sensing platforms for polycyclic aromatic hydrocarbons detection. Int J. Biosens. Bioelectron. 5, 142–148 (2019).
66. Kumar, S., Negi, S. & Maiti, P. Biological and analytical techniques used for detection of polyaromatic hydrocarbons. Environ. Sci. Pollut. Res. 24, 25810–25827 (2017).10.1007/s11356-017-0415-2 ↗
67. Sharma, H., Jain, V. K. & Khan, Z. H. Potential application of synchronous fluorescence spectroscopy to identification of PAHs in Airborne PM2.5. Pollution 8, 637–656 (2022).
68. Matuszewska, A. & Czaja, M. The use of synchronous fluorescence technique in environmental investigations of polycyclic aromatic hydrocarbons. In Environ. Emiss, edited by Richard Viskup, pp. 123-157 (IntechOpen, London, 2021).10.5772/intechopen.92402 ↗
69. Lin, D., Zou, Z., He, L. & Li, Y. Rapid screening method for simultaneous determination of four polycyclic aromatic hydrocarbons in water samples by derivative non-linear variable-angle synchronous fluorescence spectrometry. Lumin. J. Biol. Chem. Lumin. 20, 292–297 (2005).10.1002/bio.834 ↗
70. Pena, E. A., Ridley, L. M., Murphy, W. R., Sowa, J. R. & Bentivegna, C. S. Detection of polycyclic aromatic hydrocarbons (PAHs) in raw menhaden fish oil using fluorescence spectroscopy: method development. Environ. Toxicol. Chem. 34, 1946–1958 (2015).10.1002/etc.3015 ↗
71. İzgi, B. & Kander, S. Optimization of excitation and emission wavelengths for the UHPLC fluorescence detector for priority polycyclic aromatic hydrocarbons (PAHs). Acta Chromatogr. 36, 168–177 (2024).10.1556/1326.2023.01118 ↗
72. Felemban, S., Vazquez, P. & Moore, E. Future trends for in situ monitoring of polycyclic aromatic hydrocarbons in water sources: the role of immunosensing techniques. Biosensors 9, 142 (2019).10.3390/bios9040142 ↗
73. Adamiak, J. et al. First evaluation of the microbiome of built cultural heritage by using the Ion Torrent next generation sequencing platform. Int. Biodeterior. Biodegrad. 131, 11–18 (2018).10.1016/j.ibiod.2017.01.040 ↗
74. Li, Y. et al. Metagenomics of the surface of an architectural heritage site: a case study of the Ji family’s residence in the southeast of Shanxi Province, China. Coatings 15, 337 (2025).10.3390/coatings15030337 ↗
75. Roldán, C., Murcia-Mascarós, S., López-Montalvo, E., Vilanova, C. & Porcar, M. Proteomic and metagenomic insights into prehistoric Spanish Levantine Rock Art. Sci. Rep. 8, 1–10 (2018).10.1038/s41598-018-28121-6 ↗
76. He, D. et al. Insights into the bacterial and fungal communities and microbiome that causes a microbe outbreak on ancient wall paintings in the Maijishan Grottoes. Int. Biodeterior. Biodegrad. 163, 105250 (2021).10.1016/j.ibiod.2021.105250 ↗
77. Grottoli, A. et al. Nanopore sequencing and bioinformatics for rapidly identifying cultural heritage spoilage microorganisms. Front. Mater. 7, 14 (2020).10.3389/fmats.2020.00014 ↗
78. Liu, Z. et al. Identification of fungal communities associated with the biodeterioration of waterlogged archeological wood in a Han dynasty tomb in China. Front. Microbiol. 8, 1633 (2017).10.3389/fmicb.2017.01633 ↗
79. Avcil, S. Conserving 5,000 years of artifacts. J. East. Mediterr. Archaeol. Herit. Stud. 7, 386–393 (2019).
80. Gutarowska, B., Pietrzak, K., Machnowski, W. & Milczarek, J. M. Historical textiles—a review of microbial deterioration analysis and disinfection methods. Text. Res. J. 87, 2388–2406 (2017).10.1177/0040517516669076 ↗
81. MacLeod, I. D. Conservation of corroded iron artefacts-new methods for on-site preservation and cryogenic deconcreting. Int. J. Naut. Archaeol. 16, 49–56 (1987).10.1111/j.1095-9270.1987.tb01242.x ↗
82. Kono, M., Baldwin, K. G. H., Wain, A. & Rode, A. V. Treating the untreatable in art and heritage materials: ultrafast laser cleaning of ‘cloth-of-Gold’. Langmuir 31, 1596–1604 (2015).10.1021/la504400h ↗
83. Palomar, T. et al. Evaluation of laser cleaning for the restoration of tarnished silver artifacts. Appl. Surf. Sci. 387, 118–127 (2016).10.1016/j.apsusc.2016.06.017 ↗
84. Vadrucci, M. et al. Effects of the ionizing radiation disinfection treatment on historical leather. Front. Mater. 7, 503707 (2020).10.3389/fmats.2020.00021 ↗
85. Pavlakou, E. I. et al. The protection of building materials of historical monuments with nanoparticle suspensions. Heritage 4, 3970–3986 (2021).10.3390/heritage4040218 ↗
86. Fistos, T., Fierascu, I. & Fierascu, R. C. Recent developments in the application of inorganic nanomaterials and nanosystems for the protection of cultural heritage organic artifacts. Nanomater 12, 207 (2022).10.3390/nano12020207 ↗
87. Geweely, N. S. New frontiers review of some recent conservation techniques of organic and inorganic archaeological artefacts against microbial deterioration. Front. Microbiol. 14, 1146582 (2023).10.3389/fmicb.2023.1146582 ↗
88. Kamperidou, V. The biological durability of thermally-and chemically-modified black pine and poplar wood against basidiomycetes and mold action. Forests 10, 1111 (2019).10.3390/f10121111 ↗
89. Pyzik, A., Ciuchcinski, K., Dziurzynski, M. & Dziewit, L. The bad and the good—microorganisms in cultural heritage environments—an update on biodeterioration and biotreatment approaches. Mater 14, 177 (2021).10.3390/ma14010177 ↗
90. Vovk, Y., Merezhko, N., Indutnyi, V., Pirkovich, K. & Lytvynenko, Y. Determining dangerous chemicals on the surface of metallic historical artefacts. East.-Eur. J. Enterp. Technol. 6, 6–12 (2022).
91. Geweely, N. S. A novel comparative review between chemical, natural essential oils and physical (ozone) conservation of archaeological objects against microbial deterioration. Geomicrobiol. J. 39, 531–540 (2022).10.1080/01490451.2022.2043959 ↗
92. Lou, Y. et al. Microbiologically influenced corrosion inhibition mechanisms in corrosion protection: A review. Bioelectrochemistry 141, 107883 (2021).10.1016/j.bioelechem.2021.107883 ↗
93. Moradi, M., Song, Z. & Tao, X. Introducing a novel bacterium, Vibrio neocaledonicus sp., with the highest corrosion inhibition efficiency. Electrochem. Commun. 51, 64–68 (2015).10.1016/j.elecom.2014.12.007 ↗
94. Abousalem, A. S., Ismail, M. A. & Fouda, A. S. A complementary experimental and in silico studies on the action of fluorophenyl‑2,2′‑bichalcophenes as ecofriendly corrosion inhibitors and biocide agents. J. Mol. Liq. 276, 255–274 (2019).10.1016/j.molliq.2018.11.125 ↗
95. Kakakhel, M. A. et al. Controlling biodeterioration of cultural heritage objects with biocides: A review. Int. Biodeterior. Biodegrad. 143, 104721 (2019).10.1016/j.ibiod.2019.104721 ↗
96. Jiang, S., Xie, F., Lu, H., Liu, J. & Yan, C. Response of low-molecular-weight organic acids in mangrove root exudates to exposure of polycyclic aromatic hydrocarbons. Environ. Sci. Pollut. Res. 24, 12484–12493 (2017).10.1007/s11356-017-8845-4 ↗
97. Meng, Q., Li, X., Geng, J., Liu, C. & Ben, S. A biological cleaning agent for removing mold stains from paper artifacts. Herit. Sci. 11, 1–14 (2023).10.1186/s40494-023-01083-3 ↗
98. Jeszeová, L. et al. Biocleaning of historical documents: the use and characterization of bacterial enzymatic resources. Int. Biodeterior. Biodegrad. 140, 106–112 (2019).10.1016/j.ibiod.2019.03.017 ↗
99. Cappitelli, F., Cattò, C. & Villa, F. The control of cultural heritage microbial deterioration. Microorganism 8, 1542 (2020).10.3390/microorganisms8101542 ↗
100. Wang, Q., Feng, X. & Liu, X. Advances in historical wood consolidation and conservation materials. BioResources 18, 6680 (2023).10.15376/biores.18.3.Wang ↗