Flash synthesis of high-performance and color-tunable copper(I)-based cluster scintillators for efficient dynamic X-ray imaging
Source abstract
Abstract
Efficient scintillators are crucial for advancing X-ray imaging, requiring superior performance, customizable color, and cost-effectiveness. Despite progress in scintillator development, traditional synthesis methods suffer from extended reaction times, high processing temperatures, and labor-intensive post-treatment procedures. Herein, we introduce a rapid flash synthesis approach for high-performance Cu(I)-based cluster scintillators, achieved ordered assembly through solvent evaporation in 2 min. This innovative method not only accelerates synthesis but also yields scintillators with desirable features, such as wide-range luminescence tuning, a high photoluminescence quantum yield, and robust resistance to X-ray irradiation. The resulting flexible films from Cu(I)-based cluster scintillators demonstrate a low detection limit of 44 nGy s −1 and stable X-ray imaging capabilities with a resolution of 24.8 lp/mm. Additionally, the short luminescence lifetime allows the use of the flexible scintillation film for dynamic real-time imaging at a speed of 30 frames per second. The outcomes of this flash synthesis offer a strategic blueprint for the practical exploration of high-performance, large-scale, and swift synthesis of Cu(I)-based hybrid materials. This innovative technique holds the promise of significantly enhancing the efficiency and accessibility of advanced scintillators, making them more widely applicable in the field of X-ray imaging.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Lanthanide and Transition Metal Complexes · Atomic and Subatomic Physics Research · Medical Imaging Techniques and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (40)
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1. Yuan, J. et al. Highly efficient stable luminescent radical-based X-ray scintillator. J. Am. Chem. Soc. 145, 27095–27102 (2023).10.1021/jacs.3c11027 ↗
2. Shonde, T. et al. Molecular sensitization enabled high performance organic metal halide hybrid scintillator. Adv. Mater. 35, 2301612 (2023).10.1002/adma.202301612 ↗
3. Huang, R. et al. Radioluminescent Cu–Au metal nanoclusters: synthesis and self-assembly for efficient X-ray scintillation and imaging. J. Am. Chem. Soc. 145, 13816–13827 (2023).10.1021/jacs.3c02612 ↗
4. Chen, W. et al. Customizable scintillator of Cs3Cu2I5:2% In+@paper for large-area X-ray imaging. Adv. Sci. 10, 2304957 (2023).10.1002/advs.202304957 ↗
5. Zhou, Y. et al. Colloidal Cu4I4 clusters for high-resolution X-ray imaging scintillation screens. ACS Mater. Lett. 5, 2002–2008 (2023).10.1021/acsmaterialslett.3c00377 ↗
6. Luo, A. et al. Efficient metal free organic radical scintillators. Nat. Commun. 15, 8181 (2024).10.1038/s41467-024-51482-8 ↗
7. Xu, X. et al. Light management of metal halide scintillators for high-resolution X-ray imaging. Adv. Mater. 36, 2303738 (2024).10.1002/adma.202303738 ↗
8. Wang, Y., Li, M., Chai, Z., Wang, Y. & Wang, S. Perovskite scintillators for improved X-ray detection and imaging. Angew. Chem. Int. Ed. 62, e2023046 (2023).
9. Zhang, X. et al. High-performance X-ray imaging using lanthanide metal–organic frameworks. Adv. Sci. 10, 2207004 (2023).10.1002/advs.202207004 ↗
10. Liu, X. et al. Lanthanide(III)-Cu4I4 organic framework scintillators sensitized by cluster-based antenna for high-resolution X-ray imaging. Adv. Mater. 35, 2206741 (2023).10.1002/adma.202206741 ↗
11. Chen, Q. et al. All-inorganic perovskite nanocrystal scintillators. Nature 561, 88–93 (2018).10.1038/s41586-018-0451-1 ↗
12. Liang, C. et al. Thermoplastic membranes incorporating semiconductive metal–organic frameworks: An advance on flexible X-ray detectors. Angew. Chem. Int. Ed. 59, 11856–11860 (2020).10.1002/anie.202004006 ↗
13. Cui, H. et al. Lead-free organic–inorganic hybrid scintillators for X-ray detection. Aggregate 5, e454 (2023).10.1002/agt2.454 ↗
14. Liu, L. et al. Robust organogel scintillator for self-healing and ultra-flexible X-ray imaging. Adv. Mater. 36, 2311206 (2024).10.1002/adma.202311206 ↗
15. Yuan, P. et al. Hybrid thermally activated nanocluster fluorophores for X-ray scintillators. ACS Energy Lett. 8, 5088–5097 (2023).10.1021/acsenergylett.3c02050 ↗
16. Wang, H. et al. Copper organometallic iodide arrays for efficient X-ray imaging scintillators. ACS Cent. Sci. 9, 668–674 (2023).10.1021/acscentsci.2c01495 ↗
17. Zhang, N. et al. Intramolecular charge transfer enables highly-efficient X-ray luminescence in cluster scintillators. Nat. Commun. 14, 2901 (2023).10.1038/s41467-023-38546-x ↗
18. Peng, Q. et al. High performance dynamic X-ray flexible imaging realized using a copper iodide cluster-based MOF microcrystal scintillator. Angew. Chem. Int. Ed. 62, e202308194 (2023).10.1002/anie.202308194 ↗
19. Li, N. et al. Flexible, high scintillation yield Cs3Cu2I5 film made of ball-milled powder for high spatial resolution X-ray imaging. Adv. Opt. Mater. 10, 2102232 (2022).10.1002/adom.202102232 ↗
20. Wu, H. et al. One-dimensional scintillator film with benign grain boundaries for high-resolution and fast X-ray imaging. Sci. Adv. 9, eadh1789 (2023).10.1126/sciadv.adh1789 ↗
21. Su, B., Jin, J., Han, K. & Xia, Z. Ceramic wafer scintillation screen by utilizing near-unity blue-emitting lead-free metal halide (C8H20N)2Cu2Br4. Adv. Funct. Mater. 33, 2210735 (2023).10.1002/adfm.202210735 ↗
22. He, T. et al. Copper iodide inks for high-resolution X-ray imaging screens. ACS Energy Lett. 8, 1362–1370 (2023).10.1021/acsenergylett.3c00097 ↗
23. Zhu, C. et al. Supramolecular assembly of halide perovskite building blocks. J. Am. Chem. Soc. 144, 12450–12458 (2022).10.1021/jacs.2c04357 ↗
24. Ford, P., Cariati, E. & Bourassa, J. Photoluminescence properties of multinuclear copper(I) compounds. J. Chem. Rev. 99, 3625–3647 (1999).10.1021/cr960109i ↗
25. Lian, L. et al. Highly luminescent zero-dimensional organic copper halides for X-ray scintillation. J. Phys. Chem. Lett. 12, 6919–6926 (2021).10.1021/acs.jpclett.1c01946 ↗
26. Zhou, L. et al. Intrinsic self-trapped emission in 0D lead-free (C4H14N2)2In2Br10 single crystal. Angew. Chem. Int. Ed. 58, 15435–15440 (2019).10.1002/anie.201907503 ↗
27. Zhang, Y. et al. Self-trapped excitons in 2D SnP2S6 crystal with intrinsic structural distortion. Adv. Funct. Mater. 32, 2205757 (2022).10.1002/adfm.202205757 ↗
28. Li, R. et al. Ultrastable and flexible glass-ceramic scintillation films with reduced light scattering for efficient X-ray imaging. npj Flex. Electron 8, 31 (2024).10.1038/s41528-024-00319-x ↗
29. You, S. et al. Exploring a stable and dense 3D lead chloride hybrid with emission of self-trapped excitons toward X-ray scintillation. Adv. Funct. Mater. 33, 2210481 (2023).10.1002/adfm.202210481 ↗
30. Jiang, F. et al. Broadband emission origin in metal halide perovskites: Are self-trapped excitons or ions? Adv. Mater. 35, 2211088 (2023).10.1002/adma.202211088 ↗
31. Li, S. et al. One-dimensional lead-free halide with near-unity greenish-yellow light emission. Chem. Mater. 32, 6525–6531 (2020).10.1021/acs.chemmater.0c01794 ↗
32. Qiu, J. et al. Turning nonemissive CsPb2Br5 crystals into high-performance scintillators through alkali metal doping. Nano Lett. 24, 2503–2510 (2024).10.1021/acs.nanolett.3c04455 ↗
33. Feng, T. et al. Large-area transparent antimony-based perovskite glass for high-resolution X-ray imaging. ACS Nano 18, 16715–16725 (2024).10.1021/acsnano.4c01761 ↗
34. Li, H. et al. A thermo-responsive MOFs for X-ray scintillator. Adv. Mater. 36, 2405535 (2024).10.1002/adma.202405535 ↗
35. He, T. et al. Near ultraviolet-excitable cyan-emissive hybrid copper(I) halides nonlinear optical crystals with near-unity photoluminescence quantum yield and high-efficiency X-ray scintillation. Angew. Chem. Int. Ed. 63, e202407074 (2024).
36. Li, H. et al. Lead-free halide double perovskite-polymer composites for flexible X-ray imaging. J. Mater. Chem. C. 6, 11961–11967 (2018).10.1039/C8TC01564C ↗
37. Wang, Y. et al. Emergence of uranium as a distinct metal center for building intrinsic X-ray scintillators. Angew. Chem. Int. Ed. 57, 7883–7887 (2018).10.1002/anie.201802865 ↗
38. Zhu, C. et al. Supramolecular assembly of blue and green halide perovskites with near-unity photoluminescence. Science 383, 86–93 (2024).10.1126/science.adi4196 ↗
39. Wang, J. et al. Heavy-atom engineering of thermally activated delayed fluorophores for high-performance X-ray imaging scintillators. Nat. Photon. 16, 869–875 (2022).10.1038/s41566-022-01092-x ↗
40. Hu, Q. et al. Highly effective hybrid copper(I) iodide cluster emitter with negative thermal quenched phosphorescence for X-ray imaging. Angew. Chem. Int. Ed. 62, e202217784 (2023).10.1002/anie.202217784 ↗