Enabling electrospinning of medium-chain length polyhydroxyalkanoates (PHAs) by blending with short-chain length PHAs
Source abstract
Abstract
Polyhydroxyalkanoates (PHAs) have recently attracted significant attention in medical applications. Electrospinning of short chain-length (scl-)PHAs has been extensively investigated, while medium chain length (mcl-)PHAs are not suitable for electrospinning since they are elastomeric at room temperature. We improved the electrospinability of an mcl-PHA poly (3-hydroxyoctanoate-co-3-hydroxyhexanoate) (PHOHHx) by blending with a scl-PHA poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV25, with 25 mol% HV). Morphology of electrospun PHBV25/PHOHHx blends at various ratios was investigated. Effects of various processing parameters on nanofiber morphology were investigated, such as solution concentration, feeding rate and applied voltage. Crystallinity, chemical structure, and mechanical properties of the electrospun mats were also studied.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · biodegradable polymer synthesis and properties · Advanced Sensor and Energy Harvesting Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Biosystems Engineering, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, Canada
Funding
Collaborative Health Research · CHRP · NSERC
References (52)
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