Monomer conversion, release and cytotoxicity analyses of experimental GDMA-P based adhesives
Source abstract
Abstract
This study aimed to evaluate the effects of a photoinitiator system and acidic monomer (GDMA-P) concentrations on self-etch experimental dental adhesive degree of conversion (DC), monomer release and cytotoxicity. Three monomer blends containing different GDMA-P/HEMA/UDMA ratios were produced: 1/3/3; 2/3/2; and 3/3/1. CQ + EDMAB; BAPO or CQ + BAPO + EDMAB were used as photoinitiator systems. DFI was added as co-initiator, and a water/ethanol mixture was used as solvent. DC was evaluated by Fourier transform infrared spectroscopy (FTIR) ( n = 10). Monomer release was identified by ultra-high performance liquid chromatography (UHPLC) ( n = 6). The Alamar Blue assay was used to test NIH-3T3 fibroblast cell viability ( n = 8). A two-way ANOVA and Tukey post-hoc test were used for the data analyses (p < 0.05). Experimental adhesives presenting higher GDMA-P concentrations displayed an overall statistically lower DC, less monomer release and increased cell viability (p < 0.05). BAPO resulted in increased DC and lower monomer release rates than CQ only (p < 0.05). Low GDMA-P concentrations associated to BAPO generated an adhesive system with improved conversion and both lower monomer release rates and cytotoxicity.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Dental materials and restorations · Dental Research and COVID-19 · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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