journal article·2020-12-29Open access

Functionalized TiO2 Nanotube Platform for Gliadin Electroanalysis

Cristina Dumitriu, Alexandra Constantinescu, Cristian Pirvu

Crystals· Volume 11· Issue 1

Abstract

The present paper presents a gliadin detection method. This method is based on a modified Ti electrode. Modification was performed by a simple and cheap anodization. Then, a layer of graphene oxide was added, and gliadin antibody was fixed on the electrode surface. Using this complex system, electrochemical impedance spectroscopy was used for gliadin detection. Solutions with known gliadin (a fraction from gluten) content were used for analysis. Impedance measured at a certain frequency and coating resistance were analyzed. Better results (good linearity and lower detection limit) were obtained by plotting impedance at a certain frequency versus gliadin concentration. Coating resistance was proved to be in linear dependency with gliadin concentration only at lower concentrations. This system based on titanium nanostructured electrode has the potential to be used for gluten contamination detection from foods.
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Research context

OpenAlex topics: Electrochemical sensors and biosensors · Electrochemical Analysis and Applications · Biosensors and Analytical Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

General Chemistry Department, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 313 Splaiul Independentei, 060042 Bucharest, Romania

Funding

Romanian Ministry of National Education, through UEFISCDI

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