Diversity in Single- and Multiple-Component Crystals. The Search for and Prevalence of Polymorphs and Cocrystals
Source abstract
Abstract
A detailed description of polymorph screening procedures is presented. On the basis of the results of 245 polymorph screens, organic compounds were found to exist in multiple solid forms quite frequently. About 90% exhibited multiple crystalline and noncrystalline forms; about 50% exhibited polymorphism. Cocrystals are defined, and cocrystal screening is discussed. Data from 64 cocrystal screens show that cocrystals were found in 61% of the cases, and the total number of cocrystals found was 192.
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Research context
OpenAlex topics: Crystallography and molecular interactions · Crystallization and Solubility Studies · Chemical Thermodynamics and Molecular Structure
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
SSCI, an Aptuit Company, 3065 Kent Avenue, West Lafayette, Indiana 47906
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