Sol–gel grown MgO-ZnO-tricalcium-phosphate nanobioceramics: Evaluation of mechanical and degradation attributes
Source abstract
Abstract
Abstract Nanobioceramics with enhanced mechanical and degradable properties are demanding for bone tissue engineering purposes. We report the influence of partial replacement of ZnO by tricalcium phosphate (TCP) on the improved structure, degradation and mechanical properties of sol-gel grown MgO-ZnO-TCP nanobioceramics. Sample containing 40 mol% of TCP revealed homogenous distribution of fine agglomerates composed of ellipsoidal plates-like particles of average diameter ≈25.42 nm and length ≈80.93 nm. Immersion test is performed to determine the degradation characteristics of the as-prepared samples. Sample containing 40 mol% of TCP presented the lowest degradation rate and delayed loss of the compressive strength. It is established that the proposed MgO-ZnO-TCP nanobioceramic composition with good mechanical properties and corrosion resistance are prospective for biodegradable implants.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Magnesium Oxide Properties and Applications · Titanium Alloys Microstructure and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (37)
Show source-provided references
1. Sintering behavior and properties of reinforced hydroxyapatite/TCP biphasic bioceramics with ZnO whiskers10.1177/0021998310383728 ↗
2. Stimulatory effect of zinc on bone formation in tissue culture10.1016/0006-2952(87)90471-0 ↗
3. Influence of oxide-based sintering additives on densification and mechanical behavior of tricalcium phosphate (TCP)
4. Influence of ZnO/MgO substitution on sintering, crystallisation, and bio-activity of alkali-free glass-ceramics10.1016/j.msec.2015.04.023 ↗
5. Effect of ZnO addition on bioactive CaO–SiO2–P2O5–CaF2 glass–ceramics containing apatite and wollastonite10.1016/j.actbio.2006.03.001 ↗
6. Hydroxyapatite ceramics coating on magnesium alloy via a double layered capsule hydrothermal hot-pressing10.2109/jcersj2.118.749 ↗
7. Clinical evaluation of β-TCP in the treatment of lacunar bone defects: a prospective, randomized controlled study10.1016/j.msec.2012.12.041 ↗
8. Increased viable osteoblast density in the presence of nanophase compared to conventional alumina and titania particles10.1016/j.biomaterials.2003.10.090 ↗
9. Progress on the preparation of nanocrystalline apatites and surface characterization: overview of fundamental and applied aspects10.1016/j.pcrysgrow.2012.11.001 ↗
10. Nanocrystalline calcium phosphate ceramics in biomedical engineering10.1016/j.msec.2006.05.018 ↗
11. Electrocrystallization of nanocrystallite calcium phosphate coatings on titanium substrate at different current densities10.1016/j.surfcoat.2008.06.139 ↗
12. ASTM-G31-72: standard practice for laboratory immersion corrosion testing of metals · 2004
13. How useful is SBF in predicting in vivo bone bioactivity?10.1016/j.biomaterials.2006.01.017 ↗
14. Clark · 1961
15. Phase transformation and sintering behavior of Ca2P2O710.1016/S0167-577X(03)00498-1 ↗
16. Fabrication and characterization of nanocrystalline Mg-substituted fluorapatite by high energy ball milling10.1016/j.ceramint.2012.08.007 ↗
17. The relationship between porosity and strength for porous concrete10.1016/j.conbuildmat.2011.05.005 ↗
18. Effect of particle size on microstructure and strength of porous spinel ceramics prepared by pore-forming in situ technique10.1007/s12034-011-0155-8 ↗
19. 3D silk fibroinscaffold incorporating titanium dioxide (TiO2) nanoparticle (NPs) for tissue engineering10.1016/j.ijbiomac.2014.04.045 ↗
20. Fabrication and characterization of novel diopside/silk fibroin nanocomposite scaffolds for potential application in maxillofacial bone regeneration10.1016/j.ijbiomac.2013.04.004 ↗
21. Nonaqueous synthesis of manganese oxide nanoparticles structural characterization, and magnetic properties10.1021/jp067302t ↗
22. Preparation of Mg–Zn bimetallic doped Na-containing bioceramic from sodium metasilicate10.1007/s10934-016-0145-8 ↗
23. Characterization and fatigue damage of plasma sprayed {HAp} top coat with Ti and HAp/Ti bond coat layers on commercially pure titanium substrate10.1016/j.jmbbm.2008.11.001 ↗
24. Effect of reinforcements on strength of Mg 9%Al composites10.1016/j.compstruct.2004.04.019 ↗
25. Microstructure, mechanical property, bio-corrosion and cytotoxicity evaluations of Mg/HA composites10.1016/j.msec.2010.03.016 ↗
26. Microstructure, mechanical properties and bio corrosion evaluation of biodegradable AZ91 FA nanocomposites for biomedical applications10.1016/j.msea.2010.07.063 ↗
27. The effect of zirconia reinforcing agents on the microstructure and mechanical properties of hydroxyapatite-based nanocomposites10.1111/j.1551-2916.2005.00636.x ↗
28. Synthesis characterization, and antimicrobial activity of nano-hydroxyapatite-zinc for bone tissue engineering applications10.1166/jnn.2012.5142 ↗
29. Determination of anti-scale effect of hard water by test of electrodeposition10.1016/j.proeng.2012.01.1215 ↗
30. Hemolysis and cytotoxicity mechanisms of biodegradable magnesium and its alloys10.1016/j.msec.2014.08.038 ↗
31. Microstructure, mechanical property and corrosion behavior of interpenetrating (HA + β-TCP)/MgCa composite fabricated by suction casting10.1016/j.msec.2013.06.018 ↗
32. Effects of Zn2+ concentration and pH on the zinc phosphate conversion coatings on AZ31 magnesium alloy10.1016/j.corsci.2013.05.005 ↗
33. Biodegradable magnesium–hydroxyapatite metal matrix composites10.1016/j.biomaterials.2006.12.027 ↗
34. Effect of a small addition of zinc and manganese to Mg–Ca based alloys on degradation behavior in physiological media10.1016/j.jallcom.2014.12.181 ↗
35. Mechanical properties, degradation performance and cytotoxicity of Mg–Zn–Ca biomedical alloys with different compositions10.1016/j.msec.2011.07.015 ↗
36. In vitro bioactivity evaluation of magnesium-substituted fluorapatite nanopowders10.1016/j.ceramint.2011.05.157 ↗
37. Preparation and characterization of magnesium doped hydroxyapatite–gelatin nanocomposite10.1039/b418015c ↗