In vitro performance of a LDH nano capsules in-situ incorporated PEO coating loaded with naproxen sodium on Mg alloy
Source abstract
Abstract
Inflammation is an inevitable problem associated with the use of bone-implant materials. In this study, naproxen sodium-loaded layered double hydroxides (LDH) capsules were incorporated in situ into a plasma electrolytic oxidation (PEO) coating on an AZ31 Mg alloy to alleviate the inflammatory response. The results indicated that the LDHs were embedded throughout the coating formation process which reinforced the barrier properties of the PEO layer. The coating showed good antibacterial properties and excellent cell adhesion, proliferation, and differentiation abilities. An in situ drug-loaded coating with considerable corrosion resistance and long-term antibacterial effects is suggested for use in biodegradable Mg alloys.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Layered Double Hydroxides Synthesis and Applications · Magnesium Alloys: Properties and Applications · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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