journal article·2024-02Open access

Corrosion behavior of an oxide nanotube-coated β-type Ti-45Nb implant alloy in a simulated inflammatory solution

Marina Yu. Roshchina, Christine Joy Querebillo, Evgenia Dmitrieva, Andrea Voss, Noel Israel, Thomas Gemming, Lars Giebeler, Stefan Pilz, Stefan Roeher, Volker Hoffmann, Martin Hantusch, Inez M. Weidinger, Annett Gebert

Corrosion Science· Volume 227

Abstract

Oxide nanotube (ONT) layers were anodically grown on β-type Ti-45Nb and crystallized at 450°C to anatase (Ti,Nb)O2. A corrosion analysis in normal and inflammatory phosphate buffered saline (PBS) comprised electrochemical polarization studies, metal release analysis, UV-Vis and EPR measurements. In inflammatory PBS with 0.5 wt. % H2O2 (pH 5.0) amorphous ONT degraded, while crystallized ONT were most stable with lowest release. Their barrier-type behavior is attributed to their ordered crystalline nature and a fusion layer. As-ground Ti-45Nb surfaces were most reactive with highest corrosion and metal release rates. Mainly •OH radical-coordinated Ti(IV)-H2O2 complexes were detected in immersion solutions.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Titanium Alloys Microstructure and Properties · Corrosion Behavior and Inhibition

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. Review on titanium and titanium based alloys as biomaterials for orthopaedic applications10.1016/j.msec.2019.04.064 ↗
2. Bacterial adhesion on orthopedic implants10.1016/j.cis.2020.102228 ↗
3. On the design evolution of hip implants: a review10.1016/j.matdes.2022.110552 ↗
4. Research and development of metals for medical devices based on clinical needs10.1088/1468-6996/13/6/064102 ↗
5. Orthopedic applications of metallic biomaterials
6. Metal release and cell biological compatibility of beta-type Ti-40Nb containing indium10.1002/jbm.b.33976 ↗
7. Oxidation treatments of beta-type Ti-40Nb for biomedical use10.1016/j.surfcoat.2016.05.036 ↗
8. Thermomechanical processing of In-containing β-type Ti-Nb alloys10.1016/j.jmbbm.2017.12.028 ↗
9. Effect of thermomechanical processing on the mechanical biofunctionality of a low modulus Ti-40Nb alloy10.1016/j.jmbbm.2016.08.017 ↗
10. Influence of isothermal omega precipitation aging on deformation mechanisms and mechanical properties of a β-type Ti-Nb alloy10.1016/j.jallcom.2022.167309 ↗
11. Structure-property relationships of imperfect additively manufactured lattices based on triply periodic minimal surfaces10.1016/j.matdes.2022.111036 ↗
12. Controlling the Young’s modulus of a ß-type Ti-Nb alloy via strong texturing by LPBF10.1016/j.matdes.2022.110516 ↗
13. Advances in implant surface modifications to improve osseointegration10.1039/D1MA00675D ↗
14. A critical review of multifunctional titanium surfaces: New frontiers for improving osseointegration and host response, avoiding bacteria contamination10.1016/j.actbio.2018.08.013 ↗
15. Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants10.1002/adhm.201801103 ↗
16. Antibacterial titanium surfaces for medical implants10.1016/j.msec.2015.12.062 ↗
17. Promising corrosion-resistant and pre-osteoblast growth promotion performance in vitro of hydroxyapatite/TiO2 nano-porous composite coatings10.1016/j.jallcom.2021.160505 ↗
18. Electrodeposition of Sr-substituted hydroxyapatite on low modulus beta-type Ti-45Nb and effect on in vitro Sr release and cell response10.1016/j.msec.2019.110425 ↗
19. The application of titanium dioxide for deactivation of bioparticulates: an overview10.1016/j.cattod.2010.11.055 ↗
20. A review on nano Ti-based oxides for dark and photocatalysis: from photoinduced processes to bioimplant applications10.3390/nano13060982 ↗
21. The influence of surface modification on bacterial adhesion to titanium-based substrates10.1021/am507148n ↗
22. Progress in TiO2 nanotube coatings for biomedical applications: a review10.1039/C8TB00149A ↗
23. Titanium dioxide nanotubes (TNT) in energy and environmental applications: an overview10.1016/j.rser.2017.01.057 ↗
24. A critical review on the recent progress of synthesizing techniques and fabrication of TiO2-based nanotubes photocatalysts10.1016/j.apcata.2014.05.007 ↗
25. TiO2 nanotubes: synthesis and applications10.1002/anie.201001374 ↗
26. TiO2 nanotubes: self-organized electrochemical formation, properties and applications10.1016/j.cossms.2007.08.004 ↗
27. Determining the relative importance of titania nanotubes characteristics on bone implant surface performance: a quality by design study with a fuzzy approach10.1016/j.msec.2020.110995 ↗
28. A review of the application of anodization for the fabrication of nanotubes on metal implant surfaces10.1016/j.actbio.2012.04.005 ↗
29. Optimized fabrication and characterization of TiO2-Nb2O5-ZrO2 nanotubes on β-phase TiZr35Nb28 alloy for biomedical applications via the taguchi method10.1021/acsbiomaterials.9b00356 ↗
30. Surface phenomena of HA/TiN coatings on the nanotubular-structured beta Ti–29Nb–5Zr alloy for biomaterials10.1016/j.apsusc.2011.04.051 ↗
31. Morphology of nanotube arrays grown on Ti-35Nb-2Ta-3Zr alloys with different deformations10.1016/j.apsusc.2013.11.073 ↗
32. Comprehensive characterization of titania nanotubes fabricated on Ti-Nb alloys: surface topography, structure, physicomechanical behavior, and a cell culture assay10.1021/acsbiomaterials.9b01857 ↗
33. TiO2-Nb2O5 nanotubes with electrochemically tunable morphologies10.1002/anie.200601957 ↗
34. Current understanding of Ti anodisation: functional, morphological, chemical and mechanical aspects10.1515/CORRREV.2009.27.3.117 ↗
35. Titania nanostructures: a biomedical perspective10.1039/C5RA04271B ↗
36. Tailoring the immuno-responsiveness of anodized nano-engineered titanium implants10.1039/C8TB00450A ↗
37. Reduced inflammatory activity of RAW 264.7 macrophages on titania nanotube modified Ti surface10.1016/j.biocel.2014.09.006 ↗
38. The effect of anatase TiO2 nanotube layers on MC3T3-E1 preosteoblast adhesion, proliferation, and differentiation10.1002/jbm.a.32687 ↗
39. Size-effects in TiO2 nanotubes: diameter dependent anatase/rutile stabilization10.1016/j.elecom.2011.03.003 ↗
40. Time-dependent growth of biomimetic apatite on anodic TiO2 nanotubes10.1016/j.electacta.2008.01.027 ↗
41. Hydroxyapatite growth on anodic TiO2 nanotubes10.1002/jbm.a.30677 ↗
42. Diameter of titanium nanotubes influences anti-bacterial efficacy10.1088/0957-4484/22/29/295102 ↗
43. Surface treatment, corrosion behavior, and apatite-forming ability of ti-45Nb implant alloy10.1002/jbm.b.32836 ↗
44. A review on TiO2 nanotubes: influence of anodization parameters, formation mechanism, properties, corrosion behavior, and biomedical applications10.1007/s40735-015-0024-x ↗
45. Biocompatibility of implantable materials: An oxidative stress viewpoint10.1016/j.biomaterials.2016.09.010 ↗
46. The inflammasome in host response to biomaterials: bridging inflammation and tissue regeneration10.1016/j.actbio.2018.09.056 ↗
47. Modulation of the inflammatory response and bone healing10.3389/fendo.2020.00386 ↗
48. Physico-chemical considerations of titanium as a biomaterial10.1016/0267-6605(92)90056-Y ↗
49. The effect of electrochemically simulated titanium cathodic corrosion products on ROS production and metabolic activity of osteoblasts and monocytes/macrophages10.1016/j.biomaterials.2007.02.026 ↗
50. The role of oxidative stress in pro-inflammatory activation of human endothelial cells on Ti6Al4V alloy10.1016/j.biomaterials.2013.07.030 ↗
51. Corrosion of titanium under simulated inflammation conditions: clinical context and in vitro investigations10.1016/j.actbio.2021.10.002 ↗
52. Titanium-hydrogen peroxide interaction: model studies of the influence of the inflammatory response on titanium implants10.1016/0142-9612(89)90019-7 ↗
53. The influence of cathodic polarization and simulated inflammation on titanium electrochemistry10.1002/jbm.b.33123 ↗
54. A synergistic effect of albumin and H2O2 accelerates corrosion of Ti6Al4V10.1016/j.actbio.2015.07.046 ↗
55. Electrochemical and XPS studies of titanium for biomaterial applications with respect to the effect of hydrogen peroxide10.1002/jbm.820280115 ↗
56. Corrosion behavior of Ti-29Nb-13Ta-4.6Zr and commercially pure Ti under simulated inflammatory conditions – comparative effect of grain refinement and non-toxic β phase stabilizers10.1016/j.electacta.2019.04.138 ↗
57. Effect of Zr addition on the corrosion of Ti in acidic and reactive oxygen species (ROS)-containing environments10.1021/acsbiomaterials.7b00882 ↗
58. Electrochemical behaviour of ZrTi alloys in artificial physiological solution simulating in vitro inflammatory conditions10.1016/j.apsusc.2014.05.201 ↗
59. The effect of hydrogen peroxide on the electrochemical behaviour of Ti-13Nb-13Zr alloy in Hanks’ solution10.1590/S1516-14392006000400014 ↗
60. Effect of inflammatory conditions and H2O2 on bare and coated Ti–6Al–4V surfaces: Corrosion behavior, metal ion release and Ca-P formation under long-term immersion in DMEM10.1016/j.apsusc.2015.08.261 ↗
61. In vitro corrosion performance of PEO coated Ti and Ti6Al4V used for dental and orthopaedic implants10.1016/j.surfcoat.2016.08.018 ↗
62. Nanosize and vitality: TiO 2 nanotube diameter directs cell fate10.1021/nl070678d ↗
63. ATI, ATI 45NbTM Alloy Technical Data Sheet, 2012.
64. Effects of Ga on the structural, mechanical and electronic properties of β-Ti-45Nb alloy by experiments and ab initio calculations10.1016/j.jmbbm.2023.105728 ↗
65. Röntgenographische und kernmagnetische Untersuchungen am System Niob-Titan-Wasserstoff10.1515/ijmr-1983-740207 ↗
66. Rietveld analysis of electron powder diffraction data from nanocrystalline anatase, TiO210.1016/S0304-3991(99)00189-8 ↗
67. High Temperature Structures of the Rutile-Type Oxides, TiO2 and SnO210.2109/jcersj1950.92.1064_219 ↗
68. DIN EN ISO 10993–15:2009–10. Biological evaluation of medical devices - Part 15: Identification and quantification of degradation products from metals and alloys (ISO 10993–15:2000), n.d.
69. Chemical analysis - Decision limit, detection limit and determination limit under repeatability conditions - Terms, methods
70. Spin Trapping: ESR parameters of spin adducts 1474 1528V10.1016/S0891-5849(87)80033-3 ↗
71. Influence of Structure Parameters and Crystalline Phase on the Photocatalytic Activity of TiO2 Nanotube Arrays10.1166/jnn.2011.4074 ↗
72. On the Interfacial Adhesion between TiO2 Nanotube Array Layer and Ti Substrate10.1021/acs.langmuir.8b03408 ↗
73. Characterization of (Ti0.65Nb0.35)O2 compound as a source for Ti diffusion during Ti:LiNbO3 optical waveguides fabrication10.1063/1.331687 ↗
74. Niobium Alloying of Self‐Organized TiO 2 Nanotubes as an Anode for Lithium‐Ion Microbatteries10.1002/admt.201700274 ↗
75. Self-organized double-wall oxide nanotube layers on glass-forming Ti-Zr-Si(-Nb) alloys10.1016/j.msec.2016.08.068 ↗
76. Semiconducting behavior of niobium-doped titanium oxide in the amorphous state10.1063/1.3698389 ↗
77. Superior Electrochemical Performance of Amorphous Titanium Niobium Oxide Thin Films for Li-Ion Thin Film Batteries10.1149/2.0161805jes ↗
78. Pourbaix · 1966
79. Surface thermal oxidation on titanium implants to enhance osteogenic activity and in vivo osseointegration
80. Effect of indium (In) on corrosion and passivity of a beta-type Ti-Nb alloy in Ringer’s solution10.1016/j.apsusc.2015.02.058 ↗
81. Niobic acid as an unusual acidic solid material10.1016/0254-0584(87)90057-5 ↗
82. One-pot synthesis and photocatalysis of encapsulated TiO2 in mesoporous SiO210.1002/jccs.200600181 ↗
83. The diffuse reflectance spectra of some titanium oxides10.1016/0022-3697(63)90006-4 ↗
84. Synthesis of M@TiO 2 (M = Au, Pd, Pt) Core–Shell Nanocomposites with Tunable Photoreactivity10.1021/jp2009989 ↗
85. DRS UV-Vis and EPR spectroscopy of hydroperoxo and superoxo complexes in titanium silicalite10.1007/BF00764360 ↗
86. Reaction of Hydrogen Peroxide with Titanium (IV) at Different pH Values10.1246/bcsj.29.904 ↗
87. Reactive oxo-titanium species in titanosilicate molecular sieves: EPR investigations and structure-activity correlations
88. Structural evolution in a hydrothermal reaction between Nb2O5 and NaOH solution: From Nb2O5 grains to microporous Na2Nb2O6·2/3H 2O fibers and NaNbO3 cubes10.1021/ja056301w ↗
89. A Peroxoniobium Phosphate Derived from NbOPO4·3H2O10.1006/jssc.1997.7738 ↗
90. Search for reactive intermediates in catalytic oxidation with hydrogen peroxide over amorphous niobium(V) and tantalum(V) oxides10.1016/j.apcatb.2014.09.024 ↗
91. Size dependence of structural, magnetic, and electrical properties in corundum-type Ti2O 3 nanoparticles showing insulator-metal transition10.1016/j.jascer.2015.06.007 ↗
92. Electronic absorption by Ti3+ ions and electron delocalization in synthetic blue rutile10.1007/s002690050124 ↗
93. Mixed Valence Chemistry-A Survey and Classification10.1016/S0065-2792(08)60179-X ↗
94. The influence of niobium and vanadium on passivity of titanium-based implants in physiological solution10.1016/S0142-9612(03)00252-7 ↗
95. UV–Vis quantification of hydroxyl radical concentration and dose using principal component analysis10.1016/j.talanta.2020.121148 ↗
96. Studies of free-radical species from the reactions of titanium(III) ions with hydrogen peroxide10.1021/j100847a031 ↗
97. Study with fast-mixing techniques of the titanium (III) and hydrogen peroxide reaction10.1021/j100883a024 ↗
98. Electrochemical impedance spectroscopy study of the passive oxide film on titanium for implant application10.1016/0013-4686(95)00465-3 ↗
99. Corrosion behaviour of titanium in biofluids containing H2O2 studied by electrochemical impedance spectroscopy10.1016/S0010-938X(00)00107-4 ↗
100. Generation and detection of reactive oxygen species in photocatalysis10.1021/acs.chemrev.7b00161 ↗