Calcium Phosphate Bone Cement Based on Wet Prepared Dicalcium Phosphate

Calcium phosphates (CaP) were prepared by a wet chemical method. Micro-crystalline dicalcium phosphate (DCPD) was precipitated at 37°C and pH 5.0 using Ca(OH)2 and H3PO4. The precipitated DCPD solution was kept at 37°C for 96 h. Artificial bone cement was composed of DCPD, Ca(H2PO4)2 ·H2O (MCPM), and CaSO4·1/2H2O, H2O and aqueous poly-phosphoric acid solution. The wet prepared CaP powder was used as a matrix for the bone cement recipe. With the addition of aqueous poly-phosphoric acid, the cement hardening reaction was started and the CaP bone cement blocks were fabricated for the mechanical strength measurement. For the tested blocks, the mechanical strength was measured using a universal testing machine, and the microstructure phase analysis was done by field emission scanning electron microscopy and X-ray diffraction. The cement hardening reaction occurred through the decomposition and recrystallization of MCPM and CaSO4·1/2H2O added on the surface of the wet prepared CaP, and this resulted in grain growth in the bone cement block. Key words: Dicalcium phosphate precipitation, Bone cement interaction, Microcrystalline, Mechanical strength, Polyphosphoric acid