Magnetic softness and hyperthermia efficiency of Fe3O4-Au nanoparticles with silica shell
Source abstract
Abstract
Magnetite (Fe 3 O 4 ) nanoparticles (NPs) are promising agents for magnetic hyperthermia (MH) due to their high magnetization, low coercivity, and biocompatibility. Here, Fe 3 O 4 NPs were synthesized via co-precipitation, functionalized with gold (Au) for localized surface plasmon resonance (LSPR), and coated with silica (SiO 2 ) for biocompatibility and tunable plasmonic enhancement. Transmission electron microscopy (TEM) confirmed the presence of Fe 3 O 4 core with an average size of 12.5 ± 2.1 nm, Au surface decoration, and uniform SiO 2 shells of 3.7 ± 0.6 nm thickness. Magnetic measurements revealed soft ferrimagnetic behavior, with a progressive decrease in saturation magnetization upon addition of diamagnetic layers. The normalized magnetization curves indicated a slower magnetic saturation after Au integration, suggesting interfacial magnetic pinning effects. Magnetic hyperthermia tests at 310 kHz and 400–800 Oe yielded high specific absorption rate (SAR) values for Fe 3 O 4 NPs (up to 379.16 W/g) and ∼50% retention post-coating, with intrinsic loss power (ILP) values comparable to some commercial Fe 3 O 4 systems. These results highlight the potential of hybrid Fe 3 O 4 -Au@SiO 2 nanoparticles as multifunctional, biocompatible platforms.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery · Characterization and Applications of Magnetic Nanoparticles · Magnetic Properties and Synthesis of Ferrites
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (44)
Show source-provided references
1. Fine-tuning the superparamagnetic properties of FeO@Fe3O4 core/shell nanoparticles and superclusters by controlling size and shape10.1021/acsami.5c04288 ↗
2. Metal–organic framework as a new type of Magnetothermally-Triggered On-Demand release carrier
3. Multifunctional nanocarriers of Fe3O4@PLA-PEG/curcumin for MRI, magnetic hyperthermia and drug delivery10.2217/nnm-2022-0070 ↗
4. Power dissipation in magnetic nanoparticles evaluated using the AC susceptibility of their linear and nonlinear responses10.1016/j.jmmm.2020.167401 ↗
5. Recent advances in functionalized ferrite nanoparticles: from fundamentals to magnetic hyperthermia cancer therapy10.1016/j.colsurfb.2024.113754 ↗
6. Hybrid magnetic nanoparticles as efficient nanoheaters in biomedical applications10.1039/D0NA00828A ↗
7. Unlocking the potential of magnetotactic bacteria as magnetic hyperthermia agents
8. Iron oxide nanoparticles for magnetically-guided and magnetically-responsive drug delivery10.3390/ijms16048070 ↗
9. Iron oxide nanospheres and nanocubes for magnetic hyperthermia therapy: a comparative study10.1007/s11664-017-5347-6 ↗
10. Evaluation of magnetic nanoparticles for magnetic fluid hyperthermia10.1080/02656736.2019.1628313 ↗
11. Role of magnetite nanoparticles size and concentration on hyperthermia under various field frequencies and strengths10.3390/molecules26040796 ↗
12. Suitability of commercial colloids for magnetic hyperthermia10.1016/j.jmmm.2009.02.075 ↗
13. Boosted hyperthermia therapy by combined AC magnetic and photothermal exposures in Ag/Fe3O4 nanoflowers10.1021/acsami.6b09942 ↗
14. Duality of iron oxide nanoparticles in cancer therapy: amplification of heating efficiency by magnetic hyperthermia and photothermal bimodal treatment10.1021/acsnano.5b07249 ↗
15. Gold fluorescence nanoparticles for enhanced SERS detection in biomedical sensor applications: current trends and future directions
16. Potential use of SERS-assisted theranostic strategy based on Fe3O4/Au cluster/shell nanocomposites for bio-detection, MRI, and magnetic hyperthermia10.1016/j.msec.2016.03.090 ↗
17. CT and MRI imaging of theranostic bimodal Fe3O4@Au NanoParticles in tumor bearing mice
18. Artefact-free evaluation of metal enhanced fluorescence in silica coated gold nanoparticles10.1038/s41598-017-02678-0 ↗
19. Shell-isolated nanoparticle-enhanced Raman spectroscopy10.1038/nature08907 ↗
20. Interaction of gold nanoparticle with human serum albumin (HSA) protein using surface energy transfer10.1021/jp207374g ↗
21. Comprehensive multispectroscopic analysis on the interaction and Corona formation of human serum albumin with gold/silver alloy nanoparticles10.1021/acs.jpcb.5b00436 ↗
22. Characterization of biomechanical properties of agar based tissue mimicking phantoms for ultrasound stiffness imaging techniques10.1016/j.jmbbm.2014.03.017 ↗
23. Direct coating of gold nanoparticles with silica by a seeded polymerization technique10.1016/S0021-9797(03)00422-3 ↗
24. NIH image to ImageJ: 25 years of image analysis10.1038/nmeth.2089 ↗
25. Ortega
26. Development of gold-coated magnetic nanoparticles as a theranostic agent for magnetic hyperthermia and CT imaging applications10.1063/9.0000592 ↗
27. Synthesis and characterization of magnetite/gold core shell nanoparticles stabilized with a β-Cyclodextrin nanosponge to develop a magneto-plasmonic system10.3390/magnetochemistry9080202 ↗
28. Magneto-optical characteristics of streptavidin-coated Fe3O4@Au core-shell nanoparticles for potential applications on biomedical assays
29. Rational synthesis and tailored optical and magnetic characteristics of Fe3O4–Au composite nanoparticles10.1007/s10853-017-1200-9 ↗
30. Au-ultrathin functionalized core-shell (Fe3O4@Au) monodispersed nanocubes for a combination of magnetic/plasmonic photothermal cancer cell killing10.1039/c3ra21479f ↗
31. Mesoporous silica-coated gold nanoparticles for multimodal imaging and reactive oxygen species sensing of stem cells10.1021/acsanm.1c03640 ↗
32. Tuning localized surface plasmon resonance of nanoporous gold with a silica shell for surface enhanced Raman scattering
33. Effect of PVA PEG-Coated Fe3O4 nanoparticles on the structure, morphology and magnetic properties
34. Effect of Fe3O4 nanoparticles modified by citric and oleic acids on the physicochemical and magnetic properties of hybrid electrospun P(VDF-TrFE) scaffolds10.3390/polym15143135 ↗
35. Multifunctional gold coated iron oxide core-shell nanoparticles stabilized using thiolated sodium alginate for biomedical applications10.1016/j.msec.2017.05.079 ↗
36. Iron oxide nanoparticles coated with gold: enhanced magnetic moment due to interfacial effects10.1063/1.3596760 ↗
37. Effect of surfactant coating on magnetic properties of Fe3O4 nanoparticles: ESR study10.1016/j.jmmm.2005.10.112 ↗
38. Micromagnetic modeling of inter-particle interactions and their impact on hysteresis and energy in pseudo-single-domain iron nanoparticles
39. Improving the heating efficiency of iron oxide nanoparticles by tuning their shape and size10.1021/acs.jpcc.7b10528 ↗
40. On the reliable measurement of specific absorption rates and intrinsic loss parameters in magnetic hyperthermia materials10.1088/0022-3727/47/49/495003 ↗
41. Quantitation method of loss powers using commercial magnetic nanoparticles based on superparamagnetic behavior influenced by anisotropy for hyperthermia10.1016/j.jmmm.2021.168313 ↗
42. Heating magnetic fluid with alternating magnetic field10.1016/S0304-8853(02)00706-0 ↗
43. Dumbbell-like Au-Fe3O4 nanoparticles for magnetic hyperthermia
44. Ultrasmall feo@au composite nanoparticles with different sizes of FeO for magnetic hyperthermia10.1109/TMAG.2023.3287505 ↗