TiN-Ag Multilayer Protective Coatings for Surface Modification of AISI 316 Stainless Steel Medical Implants
Source abstract
Abstract
Stainless steel (SS) is one of the materials most commonly utilized for fabrication of medical implants and its properties are often improved by deposition of protective coatings. This study investigates certain physico-chemical and biological properties of SS substrate coated with multilayer thin film consisting of titanium nitride and silver layers (TiN-Ag film). TiN-Ag films were deposited on the surface of AISI 316 SS substrate by a combination of cathodic arc evaporation and DC magnetron sputtering. SS substrate was analyzed by TEM, while deposited coatings were analyzed by SEM, EDS and wettability measurements. Also, mitochondrial activity assay, and osteogenic and chondrogenic differentiation were performed on dental pulp stem cells (DPSCs). SEM and EDS revealed excellent adhesion between coatings’ layers, with the top layer predominantly composed of Ag, which is responsible for antibacterial properties. TiN-Ag film exhibited moderately hydrophilic behaviour which is desirable for orthopedic implant applications. Biological assays revealed significantly higher mitochondrial activity and enhanced osteogenic and chondrogenic differentiation of DPSC on TiN-Ag films compared to TiN films. The newly designed TiN-Ag coatings showed a great potential for the surface modification of SS implants, and further detailed investigations will explore their suitability for application in clinical practice.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Metal and Thin Film Mechanics · Titanium Alloys Microstructure and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Nuclear Sciences Vinča—National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia
School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia
Faculty of Technology and Technical Sciences, St. Kliment Ohridski University-Bitola, 1400 Veles, North Macedonia
Department of Materials Science and Engineering, Korea University, 01000 Seoul, Republic of Korea
R&D Center Plasma DOO, 1000 Skopje, North Macedonia
ALBOS DOO Belgrade, 11000 Belgrade, Serbia
Funding
Ministry of Science, Technological Development and Innovation of the Republic of Serbia
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