journal article·2022-06-24Open access

Point-of-Care Testing Blood Coagulation Detectors Using a Bio-Microfluidic Device Accompanied by Raman Spectroscopy

Song-Jeng Huang, Chao-Ching Chiang, Philip Nathaniel Immanuel, Murugan Subramania

Coatings· Volume 12· Issue 7

Abstract

An efficient technique was developed for the detection of human blood coagulation using a bio-microfluidic device based on Raman spectra [...]
Only a short abstract or summary was supplied by the source.
Source: crossref · Quality: short

Research context

OpenAlex topics: Spectroscopy Techniques in Biomedical and Chemical Research · Spectroscopy and Chemometric Analyses · Biosensors and Analytical Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan

References (26)

Show source-provided references
1. Paper microfluidics for point-of-care blood-based analysis and diagnostics10.1021/acs.analchem.8b03636 ↗
2. Detection of circulating tumor cells in blood by shell-isolated nanoparticle–enhanced Raman spectroscopy (SHINERS) in microfluidic device
3. Transformation and motility of human platelets: Details of the shape change and release reaction observed by optical and electron microscopy10.1083/jcb.83.1.126 ↗
4. Point-of-care testing of portable blood coagulation detectors using optical sensors10.5405/jmbe.1103 ↗
5. Design and evaluation of a portable optical-based biosensor for testing whole blood prothrombin time10.1016/j.talanta.2013.07.064 ↗
6. Raman spectroscopy for medical diagnostics—From in-vitro biofluid assays to in-vivo cancer detection10.1016/j.addr.2015.03.009 ↗
7. Raman spectroscopy of blood and blood components10.1177/0003702816686593 ↗
8. Raman spectroscopy offers great potential for the nondestructive confirmatory identification of body fluids10.1016/j.forsciint.2008.08.004 ↗
9. Detection and identification of aqueous saccharides by using surface-enhanced raman spectroscopy10.1021/ac020115g ↗
10. Surface-enhanced Raman spectroscopy for antiplatelet therapy effectiveness assessment10.1088/1612-202X/ab7be5 ↗
11. The influence of lipoproteins on blood platelets10.1016/0002-8703(93)90096-R ↗
12. Chiang, C.-C., Immanuel, P., Chiu, Y.-H., and Huang, S.-J. (2021). Heterogeneous Bonding of PMMA and Double-Sided Polished Silicon Wafers through H2O Plasma Treatment for Microfluidic Devices. Coatings, 11.10.3390/coatings11050580 ↗
13. Surface-enhanced raman scattering of whole human blood, blood plasma, and red blood cells: Cellular processes and bioanalytical sensing10.1021/jp304932g ↗
14. Clinical evaluation of whole blood prothrombin time (PT) and international normalized ratio (INR) using a Laser Speckle Rheology sensor10.1038/s41598-017-08693-5 ↗
15. Agreement of a new whole-blood PT/INR test using capillary samples with plasma INR determinations10.1016/j.thromres.2004.06.023 ↗
16. The role of blood clotting factor V in the conversion of prothrombin and A decarboxy prothrombin into thrombin10.1016/0304-4165(78)90413-0 ↗
17. The coagulation cascade in cirrhosis10.1016/j.cld.2008.09.014 ↗
18. Characterization of storage-induced red blood cell hemolysis using raman spectroscopy10.1093/labmed/lmy018 ↗
19. Williams, D. (2005). The Effect of Red Blood Cell Velocity on Oxygenation Measurements using Resonance Raman Spectroscopy. [Master’s Thesis, Virginia Commonwealth University].
20. Development and release of a spectral database for organic compounds-key to the continual services and success of a large-scale database
21. Raman spectroscopy of blood samples for forensic applications10.1016/j.forsciint.2010.11.012 ↗
22. Detection of methemoglobin in whole blood based on confocal micro-raman spectroscopy and multivariate statistical techniques10.1002/sca.21143 ↗
23. Effects of a low-molecular-weight heparin on thrombus regression and recurrent thromboembolism in patients with deep-vein thrombosis10.1056/NEJM200103013440902 ↗
24. Structural analysis of heparin by raman spectroscopy10.1021/js950216c ↗
25. Excitation wavelength-dependent changes in Raman spectra of whole blood and hemoglobin: Comparison of the spectra with 514.5-, 720-, and 1064-nm excitation10.1117/1.1380668 ↗
26. Rapid (<5 min) identification of pathogen in human blood by electrokinetic concentration and surface-enhanced raman spectroscopy