Fabrication and Characterization of Antimicrobial Magnetron Cosputtered TiO2/Ag/Cu Composite Coatings
Source abstract
Abstract
The aim of this study was to prepare TiO2/Ag/Cu magnetron co-sputtered coatings with controlled characteristics and to correlate them with the antimicrobial activity of the coated glass samples. The elemental composition and distribution, surface morphology, wettability, surface energy and its component were estimated as the surface characteristics influencing the bioadhesion. Well expressed, specific, Ag/Cu concentration-dependent antimicrobial activity in vitro was demonstrated toward Gram-negative and Gram-positive standard test bacterial strains both by diffusion 21 assay and by Most Probable Number of surviving cells. Direct contact and eluted silver/coper nanoparticles killing were experimentally demonstrated as a mode of the antimicrobial action of the studied TiO2/Ag/Cu thin composite coatings. It is expected that they would ensure a broad spectrum bactericidal activity during the indwelling of the coated medical devices and for at least 12 h after that, with the supposition that the benefits will be over a longer time.
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Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Dielectric properties of ceramics · TiO2 Photocatalysis and Solar Cells
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Electrical Engineering, Technical University, 8 “Kliment Ohridski” Blvd, 1756 Sofia, Bulgaria
Biological Faculty, Sofia University, “St. Kl. Ohridski”, 8 “Dragan Tsankov” Blvd, 1164 Sofia, Bulgaria
Laboratory for Advanced Materials Research, University of Chemical Technology and Metallurgy, 8 “Kliment Ohridski” Blvd, 1756 Sofia, Bulgaria
Funding
National Scientific fund, Bulgaria
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