Electophoretically Deposition of Ti3C2 on Titanium Surface for Hard Tissue Implant Applications
Source abstract
Abstract
As a metallic biomaterial, titanium (Ti) exhibits excellent biocompatibility, but its osteoinductivity is limited. Therefore, to improve this property, an electrophoretic deposition (EPD) technique was used to coat the Ti surface with Ti3C2 MXene (Ti3C2), a new class of two-dimensional nanomaterial. Ti3C2 is known to have good biocompatibility and better osteoinductivity than graphene oxide. The coating layer was characterized by a particulate microstructure and exhibited X-ray diffraction and Raman spectroscopy peaks corresponding to the Ti3C2 phase. In vitro cell tests using human mesenchymal stem cells confirmed that the cell attachment and proliferation on Ti3C2-coated Ti were similar to that of bare Ti, and that the osteoinductivity was significantly enhanced compared with bare Ti.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: MXene and MAX Phase Materials · 2D Materials and Applications · Advanced Photocatalysis Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Nano-Biomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, Korea
Department of Carbon and Nano Materials Engineering, Jeonju University, Jeonju 55069, Korea
Funding
National Research Foundation of Korea
References (33)
Show source-provided references
1. Electrosprayed calcium silicate nanoparticle-coated titanium implant with improved antibacterial activity and osteogenesis10.1016/j.colsurfb.2021.111699 ↗
2. Biofunctionalization of selective laser melted porous titanium using silver and zinc nanoparticles to prevent infections by antibiotic-resistant bacteria10.1016/j.actbio.2020.02.044 ↗
3. Outsmarting superbugs: Bactericidal activity of nanostructured titanium surfaces against methicillin- and gentamicin-resistant staphylococcus aureus atcc 3359210.1039/C9TB00102F ↗
4. Biomaterial properties of titanium in dentistry10.1016/j.job.2015.08.001 ↗
5. Anodic oxide films containing Ca and P of titanium biomaterial10.1016/S0142-9612(00)00394-X ↗
6. Application of PVD tin coating to Co-Cr-Mo based surgical implants10.1016/0142-9612(87)90085-8 ↗
7. Bone healing capacity of titanium plasma-sprayed and hydroxylapatite-coated oral implants10.1034/j.1600-0501.1998.090407.x ↗
8. Surface functionalization with strontium-containing nanocomposite coatings via EPD10.1016/j.colsurfb.2016.05.036 ↗
9. Characterization of mechanical properties of hydroxyapatite–silicon–multi walled carbon nano tubes composite coatings synthesized by EPD on niti alloys for biomedical application10.1016/j.jmbbm.2016.02.007 ↗
10. Functionalizing Ti-surfaces through the EPD of hydroxyapatite/nanoy2o310.1021/jp305176h ↗
11. Multi-walled carbon nanotube coatings using electrophoretic deposition (EPD)10.1111/j.1551-2916.2005.00155.x ↗
12. Guidelines for synthesis and processing of two-dimensional titanium carbide (Ti3C2Tx MXene)10.1021/acs.chemmater.7b02847 ↗
13. Metallic Ti3C2Tx MXene gas sensors with ultrahigh signal-to-noise ratio10.1021/acsnano.7b07460 ↗
14. MXene-based materials for electrochemical energy storage10.1016/j.jechem.2017.08.004 ↗
15. A Ti-anchored Ti2Co2 monolayer (MXene) as a single-atom catalyst for Co oxidation10.1039/C6TA00554C ↗
16. 2D ultrathin MXene-based drug-delivery nanoplatform for synergistic photothermal ablation and chemotherapy of cancer10.1002/adhm.201701394 ↗
17. Strong and biocompatible poly(lactic acid) membrane enhanced by Ti3C2Tz (MXene) nanosheets for guided bone regeneration10.1016/j.matlet.2018.06.063 ↗
18. Molecular interaction of fibrinogen with thermally modified titanium dioxide nanoparticles10.1039/C4RA07803A ↗
19. Allen-Perry, K., Straka, W., Keith, D., Han, S., Reynolds, L., Gautam, B., and Autrey, D. (2021). Tuning the magnetic properties of two-dimensional MXenes by chemical etching. Materials, 14.10.26434/chemrxiv.13523939 ↗
20. Enhanced thermal properties of poly(vinylidene fluoride) composites with ultrathin nanosheets of MXene10.1039/C7RA00184C ↗
21. Surface characteristics and bioactivity of minocycline-treated Ti-6Al-4V alloy10.21851/obr.42.04.201812.187 ↗
22. Engineered coatings for titanium implants to present ultralow doses of BMP-7
23. Effects of hydroxyapatite and biostite® on osteogenic induction of hmsc10.1007/s10439-009-9898-4 ↗
24. Relationship between surface properties (roughness, wettability and morphology) of titanium and dental implant removal torque10.1016/j.jmbbm.2007.12.002 ↗
25. 2D titanium carbide(MXene) nanosheets and 1d hydroxyapatite nanowires into free standing nanocomposite membrane: In vitro and in vivo evaluations for bone regeneration10.1016/j.msec.2020.111367 ↗
26. Multilayered titanium carbide MXene film for guided bone regeneration10.2147/IJN.S227830 ↗
27. Cytocompatibility of Ti3AlC2, Ti3SiC2, and Ti2AlN: In vitro tests and first-principles calculations10.1021/acsbiomaterials.7b00432 ↗
28. High capacitance of surface-modified 2D titanium carbide in acidic electrolyte10.1016/j.elecom.2014.09.002 ↗
29. Changes in fibroblast morphology in response to nano-columns produced by colloidal lithography10.1016/j.biomaterials.2003.12.049 ↗
30. Interaction of animal cells with ordered nanotopography10.1109/TNB.2002.806918 ↗
31. Nanostructured graphene surfaces promote different stages of bone cell differentiation10.1007/s40820-018-0198-0 ↗
32. Llopis-Grimalt, M.A., Amengual-Tugores, A.M., Monjo, M., and Ramis, J.M. (2019). Oriented cell alignment induced by a nanostructured titanium surface enhances expression of cell differentiation markers. Nanomaterials, 9.10.3390/nano9121661 ↗
33. Roughness and hydrophilicity as osteogenic biomimetic surface properties10.1089/ten.tea.2017.0048 ↗