In Vitro Corrosion and Bioactivity Performance of Surface-Treated Ti-20Nb-13Zr Alloys for Orthopedic Applications
Source abstract
Abstract
The influence of surface treatments on the microstructure, in vitro bioactivity and corrosion protection performance of newly fabricated Ti-20Nb-13Zr (TNZ) alloys was evaluated in simulated body fluid (SBF). The TNZ alloy specimens were treated with separate aqueous solutions of NaOH and H2O2 and with a mixture of both, followed by thermal treatment. The nanoporous network surface structure observed in H2O2-treated and alkali-treated specimens was entirely different from the rod-like morphology observed in alkali hydrogen peroxide-treated specimens. XRD results revealed the formation of TiO2 and sodium titanate layers on the TNZ specimens during surface treatments. The water contact angle results implied that the surface-treated specimens exhibited improved surface hydrophilicity, which probably improved the bioactivity of the TNZ specimens. The in vitro corrosion protection performance of the surface-treated TNZ specimens was analyzed using electrochemical corrosion testing in SBF, and the obtained results indicated that the surface-treated specimens exhibited improved corrosion resistance performance compared to that of the bare TNZ specimen. The in vitro bioactivity of the treated TNZ specimens was assessed by soaking in SBF, and all the investigated treated specimens showed numerous apatite nucleation spheres within 3 days of immersion in SBF.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Titanium Alloys Microstructure and Properties · Orthopaedic implants and arthroplasty · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Center of Research Excellence in Corrosion, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia
Department of Mechanical Engineering, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia
References (46)
Show source-provided references
1. Biocompatibility of β stabilizing elements of titanium alloys10.1016/j.biomaterials.2004.01.021 ↗
2. Recent research and development in titanium alloys for biomedical applications and healthcare goods10.1016/j.stam.2003.09.002 ↗
3. Ti based biomaterials, the ultimate choice for orthopaedic implants—A review10.1016/j.pmatsci.2008.06.004 ↗
4. Metallic implant biomaterials10.1016/j.mser.2014.10.001 ↗
5. Corrosion and surface modification on biocompatible metals: A review10.1016/j.msec.2017.04.102 ↗
6. Surface characterization and corrosion behavior of calcium phosphate-base composite layer on titanium and its alloys via plasma electrolytic oxidation: A review paper10.1016/j.msec.2015.07.058 ↗
7. Surface modifications of titanium materials for developing corrosion behavior in human body environment: A review10.1016/j.mspro.2014.07.144 ↗
8. Wear characteristics of metallic biomaterials: A review10.3390/ma8052749 ↗
9. Biomedical implants: Corrosion and its prevention—A review10.2174/1877610801002010040 ↗
10. In vitro bioactivity investigation of alkali treated Ti6Al7Nb alloy foams10.1016/j.apsusc.2014.12.005 ↗
11. Effect of surface treatment on electrochemical behavior of CPTi, Ti–6Al–4V and Ti–13Nb–13Zr alloys in simulated human body fluid10.1016/j.corsci.2005.06.003 ↗
12. In vitro and in vivo studies of alkali- and heat-treated Ti–6Al–7Nb and Ti–5Al–2Nb–1Ta alloys for orthopedic implants10.1002/jbm.a.32099 ↗
13. In vitro studies of hydrogen peroxide treated titanium for biomedical applications10.1016/j.electacta.2009.11.057 ↗
14. Effect of heat treatment on apatite forming ability of Ti metal induced by alkali treatment10.1023/A:1018524731409 ↗
15. Fabrication of nano-grained Ti–Nb–Zr biomaterials using spark plasma sintering10.1016/j.matdes.2015.08.082 ↗
16. Hussein, M., Kumar, M., Drew, R., and Al-Aqeeli, N. (2018). Electrochemical corrosion and in vitro bioactivity of nano-grained biomedical Ti-20Nb-13Zr alloy in a simulated body fluid. Materials, 11.
17. Hussein, M.A., and Al-Aqeeli, N. (2017). Titanium Alloys for Biomedical Applications and Fabrication Methods Thereof. (9828655B2), U.S. Patent.
18. Porous TiNbZr alloy scaffolds for biomedical applications10.1016/j.actbio.2009.06.002 ↗
19. Formation of nanoporous oxide layer over a binary β-phase titanium in simulated body fluid10.1007/s10934-011-9507-4 ↗
20. Evaluation of chemically modified Ti–5Mo–3Fe alloy surface: Electrochemical aspects and in vitro bioactivity on MG63 cells10.1016/j.apsusc.2014.03.146 ↗
21. Mechanical modulation and bioactive surface modification of porous Ti–10Mo alloy for bone implants10.1016/j.matdes.2012.05.041 ↗
22. Influence of surface modification on the apatite formation and corrosion behavior of Ti and Ti-15Mo alloy for biomedical applications10.1016/j.matchemphys.2012.11.025 ↗
23. Influence of surface treatment on PEDOT coatings: Surface and electrochemical corrosion aspects of newly developed Ti alloy10.1039/C8RA01718B ↗
24. Enhanced osseointegration of medical titanium implant with surface modifications in micro/nanoscale structures
25. Superhydrophilic/ superhydrophobic micro pattern on TiO2 nanotube films by photocatalytic lithography10.1016/j.elecom.2007.12.020 ↗
26. Mechanical bending properties of sodium titanate nanowires10.1039/C4RA11753K ↗
27. Hydrogen peroxide treatment on Ti–6Al–4V alloy: A promising surface modification technique for orthopaedic application10.1016/j.apsusc.2009.09.069 ↗
28. Kinetics of heterogeneous nucleation of calcium phosphates on anatase and rutile10.1006/jcis.1997.5329 ↗
29. PEDOT/FHA nanocomposite coatings on newly developed Ti-Nb-Zr implants: Biocompatibility and surface protection against corrosion and bacterial infections10.1016/j.msec.2019.01.012 ↗
30. Surface energy characterization of unalloyed Ti implants10.1002/jbm.820281206 ↗
31. The influence of implant surface properties on cell adhesion and proliferation10.1007/s10856-007-2006-0 ↗
32. Metastable beta Ti-Nb-Mo alloys with improved corrosion resistance in saline solution10.1016/j.electacta.2014.06.021 ↗
33. Influence of thermal treatment on the microstructure, mechanical properties, and corrosion resistance of newly developed Ti20Nb13Zr biomedical alloy in a simulated body environment10.1007/s11665-019-03908-4 ↗
34. laser nitriding of the newly developed Ti-20Nb-13Zr at.% biomaterial alloy to enhance its mechanical and corrosion properties in simulated body fluid10.1007/s11665-017-2955-5 ↗
35. Enhancement of anticorrosion property of 304 stainless steel using silane coating10.1016/j.apsusc.2018.01.203 ↗
36. Influence of Laser nitriding on the surface and corrosion properties of Ti-20Nb-13Zr alloy in artificial saliva for dental applications10.1007/s11665-018-3569-2 ↗
37. Promising hard carbon coatings on Cu substrates: Corrosion and tribological performance with theoretical aspect10.1007/s11665-018-3148-6 ↗
38. Surface modification and in vitro characterization of Cp-Ti and Ti-5Al-2Nb-1Ta alloy in simulated body fluid10.1007/s11665-012-0143-1 ↗
39. The importance of particle size in porous titanium and nonporous counterparts for surface energy and its impact on apatite formation10.1016/j.actbio.2009.02.027 ↗
40. Influence of calcium ion deposition on apatite-inducing ability of porous titanium for biomedical applications10.1016/j.actbio.2009.01.015 ↗
41. Mechanical properties and bioactive surface modification via alkali-heat treatment of a porous Ti–18Nb–4Sn alloy for biomedical applications10.1016/j.actbio.2008.04.022 ↗
42. Preliminary investigations on the anodic oxidation of Ti–13Nb–13Zr alloy in a solution containing calcium and phosphorus10.1016/j.electacta.2011.08.049 ↗
43. Variation of oxide films on titanium induced by osteoblast-like cell culture and the influence of an H2O2 pretreatment10.1002/(SICI)1097-4636(199805)40:2<244::AID-JBM9>3.0.CO;2-L ↗
44. Investigation of the electrochemical behavior and surface chemistry of a Ti–13Nb–13Zr alloy exposed in MEM cell culture media with and without the addition of H2O210.1002/sia.2616 ↗
45. Biocompatible hydrophilic brushite coatings on AZX310 and AM50 alloys for orthopaedic implants10.1007/s10856-018-6131-8 ↗
46. Investigation on the controlled degradation and in vitro mineralization of carbon nanotube reinforced AZ31 nanocomposite in simulated body fluid10.1007/s12540-018-0161-0 ↗