journal article·2020-01-01Open access

Ophthalmic Nanosystems with Antioxidants for the Prevention and Treatment of Eye Diseases

Elena Dinte, Oliviu Vostinaru, Ovidiu Samoila, Bogdan Sevastre, Ede Bodoki

Coatings· Volume 10· Issue 1

Abstract

Oxidative stress may induce a series of pathophysiological modifications that are directly involved in the development of ophthalmic diseases like age-related cataract, macular degeneration or diabetic retinopathy, considered to be responsible for the majority of vision loss cases. Although various treatment options for eye diseases are available, multiple factors could limit their efficacy. Recently, the accelerated development of ophthalmic nanosystems has provided new possibilities for overcoming the limitations of existing ocular drug delivery methods. This review evaluates the current status of ophthalmic nanosystems loaded with antioxidants for the prevention and treatment of several eye diseases.
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Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoplatforms for cancer theranostics · Sulfur Compounds in Biology

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Pharmaceutical Technology and Biopharmaceutics, Iuliu Hatieganu University of Medicine and Pharmacy, 41 V. Babes Street, 400012 Cluj-Napoca, Romania

Department of Pharmacology, Physiology and Physiopathology, Iuliu Hatieganu University of Medicine and Pharmacy, 6 L. Pasteur Street, 400349 Cluj-Napoca, Romania

Department of Ophthalmology, Iuliu Hatieganu University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania

Department of Pathophysiology, University of Agricultural Sciences and Veterinary Medicine, 3 Calea Manastur Street, 400374 Cluj-Napoca, Romania

Department of Analytical Chemistry, Iuliu Hatieganu University of Medicine and Pharmacy, 4 L. Pasteur Street, 400349 Cluj-Napoca, Romania

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